« Intelligence artificielle » : quels services, quelles applications, quels résultats et quelle valorisation aujourd’hui en recherche clinique ? Quel impact sur la qualité des soins ? Quelles recommandations ?

Autor: Philippe Barthélémy, François-Henri Boissel, Nacer Boubenna, Vincent Diebolt, J Longin, Isabelle Adenot, Anne Metzinger, Xosé M Fernández, Christine Balague, Enguerrand Habran, Pierre Philip, Emmanuel Pham, Thierry Marchal, William Saurin, Françoise Lethiec, Anny Tirel, Thomas Roche, Emmanuelle M. Voisin, Isaac Azancot, Hélène Coulonjou, Yvon Merlière

Publikováno v: Thérapie
Thérapie, EDP Sciences, 2019, 74, pp.141-154. ⟨10.1016/j.therap.2018.11.006⟩

Resume L’intelligence artificielle (IA), au-dela des applications concretes qui ont deja integre notre quotidien, permet de traiter des donnees et des connaissances nombreuses et heterogenes, et de comprendre des regles potentiellement complexes et

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7115750f1dc9477788fecd0b2d63109f
https://doi.org/10.1016/j.therap.2018.11.006

The DNA sequence and analysis of human chromosome 14

Autor: Roland Heilig, Ralph Eckenberg, Jean-Louis Petit, Núria Fonknechten, Corinne Da Silva, Laurence Cattolico, Michaël Levy, Valérie Barbe, Véronique de Berardinis, Abel Ureta-Vidal, Eric Pelletier, Virginie Vico, Véronique Anthouard, Lee Rowen, Anup Madan, Shizhen Qin, Hui Sun, Hui Du, Kymberlie Pepin, François Artiguenave, Catherine Robert, Corinne Cruaud, Thomas Brüls, Olivier Jaillon, Lucie Friedlander, Gaelle Samson, Philippe Brottier, Susan Cure, Béatrice Ségurens, Franck Anière, Sylvie Samain, Hervé Crespeau, Nissa Abbasi, Nathalie Aiach, Didier Boscus, Rachel Dickhoff, Monica Dors, Ivan Dubois, Cynthia Friedman, Michel Gouyvenoux, Rose James, Anuradha Madan, Barbara Mairey–Estrada, Sophie Mangenot, Nathalie Martins, Manuela Ménard, Sophie Oztas, Amber Ratcliffe, Tristan Shaffer, Barbara Trask, Benoit Vacherie, Chadia Bellemere, Caroline Belser, Marielle Besnard-Gonnet, Delphine Bartol–Mavel, Magali Boutard, Stéphanie Briez-Silla, Stephane Combette, Virginie Dufossé-Laurent, Carolyne Ferron, Christophe Lechaplais, Claudine Louesse, Delphine Muselet, Ghislaine Magdelenat, Emilie Pateau, Emmanuelle Petit, Peggy Sirvain-Trukniewicz, Arnaud Trybou, Nathalie Vega-Czarny, Elodie Bataille, Elodie Bluet, Isabelle Bordelais, Maria Dubois, Corinne Dumont, Thomas Guérin, Sébastien Haffray, Rachid Hammadi, Jacqueline Muanga, Virginie Pellouin, Dominique Robert, Edith Wunderle, Gilbert Gauguet, Alice Roy, Laurent Sainte-Marthe, Jean Verdier, Claude Verdier-Discala, LaDeana Hillier, Lucinda Fulton, John McPherson, Fumihiko Matsuda, Richard Wilson, Claude Scarpelli, Gábor Gyapay, Patrick Wincker, William Saurin, Francis Quétier, Robert Waterston, Leroy Hood, Jean Weissenbach

Publikováno v: Nature. 421:601-607

Chromosome 14 is one of five acrocentric chromosomes in the human genome. These chromosomes are characterized by a heterochromatic short arm that contains essentially ribosomal RNA genes, and a euchromatic long arm in which most, if not all, of the p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d820ff4ceb97c145e8557acff982ef2
https://doi.org/10.1038/nature01348

Genomic Exploration of the Hemiascomycetous Yeasts: 18. Comparative analysis of chromosome maps and synteny withSaccharomyces cerevisiae

Autor: Michel Aigle, Gaëlle Blandin, Patrick Wincker, Micheline Wésolowski-Louvel, Elisabeth Bon, Monique Bolotin-Fukuhara, Fredj Tekaia, Jean-Luc Souciet, Odile Ozier-Kalogeropoulos, Cécile Neuvéglise, Claude Gaillardin, Serge Potier, Philippe Brottier, Jean Weissenbach, William Saurin, François Artiguenave, Bernard Dujon, Claire Toffano-Nioche, Jacky de Montigny, Serge Casaregola, Alain Malpertuy, Pascal Durrens, Bertrand Llorente, Andrée Lépingle

Publikováno v: FEBS Letters. 487:101-112

We have analyzed the evolution of chromosome maps of Hemiascomycetes by comparing gene order and orientation of the 13 yeast species partially sequenced in this program with the genome map of Saccharomyces cerevisiae. From the analysis of nearly 8000

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d249e17f4c1d364b4908cf0dcc08bc2b
https://doi.org/10.1016/s0014-5793(00)02289-4

Genomic Exploration of the Hemiascomycetous Yeasts: 1. A set of yeast species for molecular evolution studies1

Autor: Jean Weissenbach, Patrick Wincker, Philippe Brottier, Monique Bolotin-Fukuhara, Micheline Wésolowski-Louvel, Michel Aigle, Cécile Neuvéglise, Fredj Tekaia, Claire Toffano-Nioche, Claude Gaillardin, Jacky de Montigny, Bernard Dujon, Odile Ozier-Kalogeropoulos, Gaëlle Blandin, Serge Casaregola, Serge Potier, Alain Malpertuy, Elisabeth Bon, Pascal Durrens, Bertrand Llorente, Andrée Lépingle, William Saurin, Jean-Luc Souciet, François Artiguenave

Publikováno v: FEBS Letters. 487:3-12

The identification of molecular evolutionary mechanisms in eukaryotes is approached by a comparative genomics study of a homogeneous group of species classified as Hemiascomycetes. This group includes Saccharomyces cerevisiae, the first eukaryotic ge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f46ef45d74bad9d54c24cefb8ac81595
https://doi.org/10.1016/s0014-5793(00)02272-9

Getting In or Out: Early Segregation Between Importers and Exporters in the Evolution of ATP-Binding Cassette (ABC) Transporters

Autor: William Saurin, Maurice Hofnung, Elie Dassa

Publikováno v: Journal of Molecular Evolution. 48:22-41

ATP-binding cassette (ABC) systems, also called traffic ATPases, are found in eukaryotes and prokaryotes and almost all participate in the transport of a wide variety of molecules. ABC systems are characterized by a highly conserved ATPase module cal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daaddc18ffe923308b768f93ab8921ab
https://doi.org/10.1007/pl00006442