Výsledky vyhledávání - "William S. Oetting"

Akademický článek

The Human Genome Organisation (HUGO) and a vision for Ecogenomics: the Ecological Genome Project

Autor: Benjamin Capps, Ruth Chadwick, Zohar Lederman, Tamra Lysaght, Catherine Mills, John J. Mulvihill, William S. Oetting, Ingrid Winship, HUGO Committee on Ethics, Law and Society

Publikováno v: Human Genomics, Vol 17, Iss 1, Pp 1-7 (2023)

Abstract Background The following outlines ethical reasons for widening the Human Genome Organisation’s (HUGO) mandate to include ecological genomics. Main The environment influences an organism’s genome through ambient factors in the biosphere (

Externí odkaz: https://doaj.org/article/c078174a34af464e8d73d1a10f929176

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Akademický článek

A Multi-Marker Test for Analyzing Paired Genetic Data in Transplantation

Autor: Victoria L. Arthur, Zhengbang Li, Rui Cao, William S. Oetting, Ajay K. Israni, Pamala A. Jacobson, Marylyn D. Ritchie, Weihua Guan, Jinbo Chen

Publikováno v: Frontiers in Genetics, Vol 12 (2021)

Emerging evidence suggests that donor/recipient matching in non-HLA (human leukocyte antigen) regions of the genome may impact transplant outcomes and recognizing these matching effects may increase the power of transplant genetics studies. Most avai

Externí odkaz: https://doaj.org/article/7656d520342b44fba34ee50ca12f3e19

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Donor and recipient polygenic risk scores influence the risk of post-transplant diabetes

Autor: Abraham Shaked, Bao-Li Loza, Elisabet Van Loon, Kim M. Olthoff, Weihua Guan, Pamala A. Jacobson, Andrew Zhu, Claire E. Fishman, Hui Gao, William S. Oetting, Ajay K. Israni, Giuliano Testa, James Trotter, Goran Klintmalm, Maarten Naesens, Sumeet K. Asrani, Brendan J. Keating

Publikováno v: Nature Medicine. 28:999-1005

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::044a4d09379e4640e250bd7f444c036f
https://doi.org/10.1038/s41591-022-01758-7

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Whole Exome Sequencing Identifies Somatic Variants in an Oral Composite Hemangioendothelioma Characterized by YAP1-MAML2 Fusion

Autor: William S. Oetting, Gregory M Burns, Rajaram Gopalakrishnan, Cristina R. Antonescu, Ioannis G. Koutlas

Publikováno v: Head and Neck Pathology. 16:849-856

Composite hemangioendothelioma (CHE) is considered a borderline malignant vascular tumor defined by an admixture of distinct vascular neoplastic components. A 21-year-old female is presented herein with a 1 cm painless mandibular vestibular mass of l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::beba4bdefafd3207b5e432452c262906
https://doi.org/10.1007/s12105-021-01393-7

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Knowledge and attitudes of incoming pharmacy students toward pharmacogenomics and survey reliability

Autor: Ya-Feng Wen, Pamala A Jacobson, William S Oetting, Chrystian Pereira, Jacob T Brown

Publikováno v: Pharmacogenomics. 23(16)

bAims:/bTo assess knowledge and attitudes toward pharmacogenomics (PGx) of incoming doctoral pharmacy students, to evaluate the internal structure and reliability of the PGx survey and to identify variables associated with the different responses.bMe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7cd9a3db638787adac277637beba10e
https://pubmed.ncbi.nlm.nih.gov/36314296

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Higher number of tacrolimus dose adjustments in kidney transplant recipients who are extensive and intermediate CYP3A5 metabolizers

Autor: Kevin A. Reininger, Guillaume Onyeaghala, Teresa Anderson‐Haag, David S. Schladt, Baolin Wu, Weihua Guan, Casey R. Dorr, Rory P. Remmel, Roslyn Mannon, Arthur J. Matas, William S. Oetting, Paul Stahler, Ajay K. Israni, Pamala A. Jacobson

Publikováno v: Clinical transplantation.

Kidney transplant recipients carrying the CYP3A5*1 allele have lower tacrolimus troughs, and higher dose requirements compared to those with the CYP3A5*3/*3 genotype. However, data on the effect of CYP3A5 alleles on post-transplant tacrolimus managem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a84d5e55d2573b1fef047a101187e30
https://pubmed.ncbi.nlm.nih.gov/36571802

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Akademický článek

Differentially expressed gene transcripts using RNA sequencing from the blood of immunosuppressed kidney allograft recipients.

Autor: Casey Dorr, Baolin Wu, Weihua Guan, Amutha Muthusamy, Kinjal Sanghavi, David P Schladt, Jonathan S Maltzman, Steven E Scherer, Marcia J Brott, Arthur J Matas, Pamala A Jacobson, William S Oetting, Ajay K Israni

Publikováno v: PLoS ONE, Vol 10, Iss 5, p e0125045 (2015)

We performed RNA sequencing (RNAseq) on peripheral blood mononuclear cells (PBMCs) to identify differentially expressed gene transcripts (DEGs) after kidney transplantation and after the start of immunosuppressive drugs. RNAseq is superior to microar

Externí odkaz: https://doaj.org/article/e36481d1a5dc4a60b1328e47bbb647b2

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