Zobrazeno 1 - 10
of 209
pro vyhledávání: '"William S. M. Wold"'
Autor:
J. Milburn Jessup, Mohamed Kabbout, Nikolay Korokhov, Alex Joun, Ann E. Tollefson, William S. M. Wold, Abid R. Mattoo
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 16, Iss 3, Pp 636-644 (2020)
Treatments with cytotoxic agents or viruses may cause Immunogenic Cell Death (ICD) that immunize tumor-bearing hosts but do not cause complete regression of tumor. We postulate that combining two ICD inducers may cause durable regression in immunocom
Externí odkaz:
https://doaj.org/article/7622a97b8b444b8e842a4c3dfe239e59
Autor:
Rong Li, Baoling Ying, Yanan Liu, Jacqueline F. Spencer, Jinxin Miao, Ann E. Tollefson, James D. Brien, Yaohe Wang, William S. M. Wold, Zhongde Wang, Karoly Toth
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 8 (2020)
Model animals are indispensable for the study of human diseases, and in general, of complex biological processes. The Syrian hamster is an important model animal for infectious diseases, behavioral science and metabolic science, for which more experi
Externí odkaz:
https://doaj.org/article/611314544fa547a78f2bb3a67999d999
Autor:
Karoly Toth, Baoling Ying, Ann E. Tollefson, Jacqueline F. Spencer, Lata Balakrishnan, John E. Sagartz, Robert Mark L. Buller, William S. M. Wold
Publikováno v:
Viruses, Vol 7, Iss 3, Pp 1409-1428 (2015)
Adenovirus infections of immunocompromised pediatric hematopoietic stem cell transplant patients can develop into serious and often deadly multi-organ disease. There are no drugs approved for adenovirus infections. Cidofovir (an analog of 2-deoxycyti
Externí odkaz:
https://doaj.org/article/50ff05ddc4ce4937b99930b25d086754
Autor:
Scott Parker, Leonardo Camilo de Oliveira, Elliot J. Lefkowitz, Robert Curtis Hendrickson, Cláudio A. Bonjardim, William S. M. Wold, Hollyce Hartzler, Ryan Crump, Robert Mark Buller
Publikováno v:
Viruses, Vol 10, Iss 9, p 463 (2018)
Taterapox virus (TATV) is phylogenetically the closest related virus to variola—the etiological agent of smallpox. Despite the similarity, few studies have evaluated the virus. In vivo, TATV can infect several animals but produces an inapparent inf
Externí odkaz:
https://doaj.org/article/1c8e6c0e40344b098b4b0d5d01435ed9
Autor:
William S. M. Wold, Karoly Toth
Publikováno v:
Viruses, Vol 2, Iss 9, Pp 1844-1866 (2010)
Oncolytic adenovirus (Ad) vectors present a new modality to treat cancer. These vectors attack tumors via replicating in and killing cancer cells. Upon completion of the vector replication cycle, the infected tumor cell lyses and releases progeny vir
Externí odkaz:
https://doaj.org/article/0a50c7501a3d4bf18bf7ce00437e652d
Autor:
Elke Lipka, Aaron M. Chadderdon, Cheryl C. Harteg, Matthew K. Doherty, Eric S. Simon, John M. Domagala, Dawn M. Reyna, Kim M. Hutchings, Xinmin Gan, Andrew D. White, Caroll B. Hartline, Emma A. Harden, Kathy A. Keith, Mark N. Prichard, Scott H. James, Rhonda D. Cardin, David I. Bernstein, Jacqueline F. Spencer, Ann E. Tollefson, William S. M. Wold, Karoly Toth
Publikováno v:
Molecular pharmaceutics. 20(1)
DNA viruses are responsible for many diseases in humans. Current treatments are often limited by toxicity, as in the case of cidofovir (CDV, Vistide), a compound used against cytomegalovirus (CMV) and adenovirus (AdV) infections. CDV is a polar molec
Autor:
Nikolay Korokhov, Alex Joun, William S. M. Wold, Ann E. Tollefson, J. Milburn Jessup, Abid R. Mattoo, Mohamed Kabbout
Publikováno v:
Human Vaccines & Immunotherapeutics
Treatments with cytotoxic agents or viruses may cause Immunogenic Cell Death (ICD) that immunize tumor-bearing hosts but do not cause complete regression of tumor. We postulate that combining two ICD inducers may cause durable regression in immunocom
Autor:
Jacqueline F. Spencer, Karoly Toth, Baoling Ying, Ann E. Tollefson, Mark N. Prichard, William S. M. Wold, Islam T. M. Hussein, Terry L. Bowlin, Scott H. James, Jessica Eagar
Publikováno v:
Antimicrob Agents Chemother
Human adenovirus (HAdV) infection is common in the general population and can cause a range of clinical manifestations, among which pneumonia and keratoconjunctivitis are the most common. Although HAdV infections are mostly self-limiting, infections
Autor:
Karoly Toth, Jinxin Miao, James D. Brien, Yanan Liu, Ann E. Tollefson, Zhongde Wang, Rong Li, Yaohe Wang, William S. M. Wold, Jacqueline F. Spencer, Baoling Ying
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 8 (2020)
Model animals are indispensable for the study of human diseases, and in general, of complex biological processes. The Syrian hamster is an important model animal for infectious diseases, behavioral, and metabolic science for which more experimental t
Autor:
Robert Klopfleisch, Jens Kurreck, Henry Fechner, Baoling Ying, Karoly Toth, Markian Pryshliak, Ann E. Tollefson, Anja Geisler, Milena Kraus, Sandra Pinkert, Katrin Schaar, Jacqueline F. Spencer, William S. M. Wold
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 8, Iss, Pp 300-316 (2017)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
Infections of immunocompromised patients with human adenoviruses (hAd) can develop into life-threatening conditions, whereas drugs with anti-adenoviral efficiency are not clinically approved and have limited efficacy. Small double-stranded RNAs that