Zobrazeno 1 - 10
of 28
pro vyhledávání: '"William S. Lawrence"'
Autor:
Paul B. Kilgore, Jian Sha, Emily K. Hendrix, Blake H. Neil, William S. Lawrence, Jennifer E. Peel, Lauren Hittle, Joelle Woolston, Alexander Sulakvelidze, Jennifer A. Schwartz, Ashok K. Chopra
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 11 (2024)
ABSTRACT Yersinia pestis, one of the deadliest bacterial pathogens ever known, is responsible for three plague pandemics and several epidemics, with over 200 million deaths during recorded history. Due to high genomic plasticity, Y. pestis is amenabl
Externí odkaz:
https://doaj.org/article/fbed38d6bf6e45e684e5b7589c485d06
Autor:
B. Kim Lee Sim, Minglin Li, Manuel Osorio, Yun Wu, Tint T. Wai, Johnny W. Peterson, Eric R. James, Sumana Chakravarty, Lixin Gao, Rui Xu, Natasha KC, Richard E. Stafford, William S. Lawrence, Linsey A. Yeager, Jennifer E. Peel, Satheesh K. Sivasubramani, Ashok K. Chopra, Svetlana Filippova, Stephen L. Hoffman
Publikováno v:
npj Vaccines, Vol 2, Iss 1, Pp 1-7 (2017)
Counterterrorism: creating a safe, stable, easily stored anthrax vaccine A vaccine candidate for anthrax infection shows promise for improving preparedness for a biological attack. Bacillus anthracis, the bacterium responsible for anthrax is a top-ti
Externí odkaz:
https://doaj.org/article/e6ed55cb74e9406db34a5f3fb0bf3838
Autor:
William S. Lawrence, Jennifer E. Peel, Satheesh K. Sivasubramani, Wallace B. Baze, Elbert B. Whorton, David W. C. Beasley, Jason E. Comer, Dallas E. Hughes, Losee L. Ling, Johnny W. Peterson
Publikováno v:
Pathogens, Vol 9, Iss 9, p 773 (2020)
The use of antibiotics is a vital means of treating infections caused by the bacteria Bacillus (B.) anthracis. Importantly, with the potential future use of multidrug-resistant strains of B. anthracis as bioweapons, new antibiotics are needed as alte
Externí odkaz:
https://doaj.org/article/3a2163ea774f4eb198d83dbe641669d8
Autor:
Pan Tao, Marthandan Mahalingam, Jingen Zhu, Mahtab Moayeri, Jian Sha, William S. Lawrence, Stephen H. Leppla, Ashok K. Chopra, Venigalla B. Rao
Publikováno v:
mBio, Vol 9, Iss 5 (2018)
ABSTRACT Bacillus anthracis and Yersinia pestis, the causative agents of anthrax and plague, respectively, are two of the deadliest pathogenic bacteria that have been used as biological warfare agents. Although Biothrax is a licensed vaccine against
Externí odkaz:
https://doaj.org/article/8e99a89944ec4a70998d621b245a3deb
Autor:
Pan Tao, Marthandan Mahalingam, Jingen Zhu, Mahtab Moayeri, Michelle L. Kirtley, Eric C. Fitts, Jourdan A. Andersson, William S. Lawrence, Stephen H. Leppla, Ashok K. Chopra, Venigalla B. Rao
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Bioterrorism remains as one of the biggest challenges to global security and public health. Since the deadly anthrax attacks of 2001 in the United States, Bacillus anthracis and Yersinia pestis, the causative agents of anthrax and plague, respectivel
Externí odkaz:
https://doaj.org/article/8a34650f189348629f8a72016ea0aada
Autor:
Johnny W. Peterson, Elbert B. Whorton, Randy L. Gourley, Wallace B. Baze, Scott T. Moen, Lori E. Weaver, Diana L. Zavala, Jeffrey R. Marshall, William S. Lawrence
Publikováno v:
Toxins, Vol 3, Iss 6, Pp 721-736 (2011)
Anthrax lethal toxin (LeTx) and edema toxin (EdTx) have been shown to alter hemodynamics in the rodent model, while LeTx primarily is reported to induce extensive tissue pathology. However, the rodent model has limitations when used for comparison to
Externí odkaz:
https://doaj.org/article/b7422fc0b9f042098f001aba100456c2
Autor:
Abhishek N Prasad, Karla A Fenton, Krystle N Agans, Viktoriya Borisevich, Courtney Woolsey, Jason E Comer, Natalie S Dobias, Jennifer E Peel, Daniel J Deer, Joan B Geisbert, William S Lawrence, Robert W Cross, Thomas W Geisbert
Publikováno v:
The Journal of Infectious Diseases.
Background The primary route of infection by Ebola virus (EBOV) and other pathogenic filoviruses in humans is through contact of contaminated body fluids with mucosal surfaces. Despite this, filoviruses hold capacity for delivery by both large and sm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc535f03665de0637773f29e963e636b
https://doi.org/10.1093/infdis/jiad137
https://doi.org/10.1093/infdis/jiad137
Autor:
William S. Lawrence, Jennifer E. Peel, Richard Slayden, Johnny W. Peterson, Wallace B. Baze, Martha E. Hensel, Elbert B. Whorton, David W.C. Beasley, Jason E. Cummings, Ines Macias-Perez
Anthrax, caused by the bacteriumBacillus anthracis, is a zoonotic disease that manifests in various forms in human infection, depending on the route of infection. Inhalation anthrax, the most detrimental form of the disease, comes about from the inha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::886d40adba9241cba40778b6ff275dd7
https://doi.org/10.1101/2023.02.13.528259
https://doi.org/10.1101/2023.02.13.528259
Autor:
Christopher K. Cote, Jennifer E. Peel, Samandra T. Demons, Jennifer K Tran, Lynda L. Miller, Chi-Lee C. Ho, Satheesh K Sivasubramani, Chiu-Yen Kao, Jennifer L. Shoe, David P Fetterer, Mikhail Martchenko Shilman, Johnny W. Peterson, Gloria Bartolo, Ryan C. McComb, Saleem Alameh, Kenneth A. Bradley, David W.C. Beasley, Stella Hartmann, Emiene Amali-Adekwu, William S Lawrence, Anastasia Levitin, Marina Chugunova, Joel West, Leeor Zilbermintz, Christopher P. Klimko, Luisa W. Cheng, Aram Derbedrossian, Stephanie A Halasahoris
Publikováno v:
ACS Infect Dis
[Image: see text] Anthrax is caused by Bacillus anthracis and can result in nearly 100% mortality due in part to anthrax toxin. Antimalarial amodiaquine (AQ) acts as a host-oriented inhibitor of anthrax toxin endocytosis. Here, we determined the phar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df80135ee02f50492e189d514256fed9
https://doi.org/10.1021/acsinfecdis.1c00190
https://doi.org/10.1021/acsinfecdis.1c00190
Autor:
H. William S. Lawrence, Kenneth S. Plante, Divya Mirchandani, Alexander Tibbens, Eryu Wang, Jason E. Comer, Igor S. Lukashevich, Jennifer E. Peel, Tek N. Lamichhane, Irina Tretyakova, Peter Pushko, Shannan L. Rossi, Scott C. Weaver, Sif Gudjohnsen
Publikováno v:
Vaccine. 38:3378-3386
Live-attenuated V4020 vaccine for Venezuelan equine encephalitis virus (VEEV) containing attenuating rearrangement of the virus structural genes was evaluated in a non-human primate model for immunogenicity and protective efficacy against aerosol cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ce46193d6cfda274e97143cc74a3232
https://doi.org/10.1016/j.vaccine.2020.02.007
https://doi.org/10.1016/j.vaccine.2020.02.007