Zobrazeno 1 - 10
of 18
pro vyhledávání: '"William S. Hambright"'
Autor:
Xianlin Yue, Jie Cui, Zewei Sun, Lei Liu, Ying Li, Liwei Shao, Qi Feng, Ziyue Wang, William S. Hambright, Yan Cui, Johnny Huard, Yanling Mu, Xiaodong Mu
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-11 (2023)
Abstract Nuclear decoupling and softening are the main cellular mechanisms to resist mechanical stress-induced nuclear/DNA damage, however, its molecular mechanisms remain much unknown. Our recent study of Hutchinson-Gilford progeria syndrome (HGPS)
Externí odkaz:
https://doaj.org/article/ce6bf7102cf34b47b974a1ba73ecb606
Autor:
Lei Liu, Xianlin Yue, Zewei Sun, William S. Hambright, Jianming Wei, Ying Li, Polina Matre, Yan Cui, Zhihui Wang, George Rodney, Johnny Huard, Paul D. Robbins, Xiaodong Mu
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 6, Pp 3137-3148 (2022)
Abstract Background Fibro‐adipogenic progenitors (FAPs) in the muscles have been found to interact closely with muscle progenitor/stem cells (MPCs) and facilitate muscle regeneration at normal conditions. However, it is not clear how FAPs may inter
Externí odkaz:
https://doaj.org/article/bd57a20665ce40cbb7dcd884505dbe4d
Autor:
William S. Hambright, Xiaodong Mu, Xueqin Gao, Ping Guo, Yohei Kawakami, John Mitchell, Michael Mullen, Anna-Laura Nelson, Chelsea Bahney, Haruki Nishimura, Justin Hellwinkel, Andrew Eck, Johnny Huard
Publikováno v:
Journal of Osteoporosis, Vol 2023 (2023)
Aging leads to several geriatric conditions including osteoporosis (OP) and associated frailty syndrome. Treatments for these conditions are limited and none target fundamental drivers of pathology, and thus identifying strategies to delay progressiv
Externí odkaz:
https://doaj.org/article/2beef3c3f7ee472b8101fa6693ed2c82
Autor:
Sarah L. Ullevig, Hong Seok Kim, Huynh Nga Nguyen, William S. Hambright, Andrew J. Robles, Sina Tavakoli, Reto Asmis
Publikováno v:
Redox Biology, Vol 2, Iss C, Pp 259-266 (2014)
Aims: Dietary supplementation with ursolic acid (UA) prevents monocyte dysfunction in diabetic mice and protects mice against atherosclerosis and loss of renal function. The goal of this study was to determine the molecular mechanism by which UA prev
Externí odkaz:
https://doaj.org/article/1002e22c1bb6423e972d541a857db82f
Autor:
Lei Liu, Xianlin Yue, Zewei Sun, William S. Hambright, Qi Feng, Yan Cui, Johnny Huard, Paul D. Robbins, Zhihui Wang, Xiaodong Mu
Publikováno v:
Aging. 14:7650-7661
The aging of the immune system, or immunosenescence, was recently verified to have a causal role in driving the aging of solid organs, while the senolytic elimination of senescent immune cells was found to effectively delay systemic aging. Our recent
Publikováno v:
Aging cellREFERENCES.
Mesenchymal-derived stromal or progenitor cells, commonly called "MSCs," have attracted significant clinical interest for their remarkable abilities to promote tissue regeneration and reduce inflammation. Recent studies have shown that MSCs' therapeu
Autor:
Michael Mullen, Katherine Williams, Tom LaRocca, Victoria Duke, William S. Hambright, Sudheer K. Ravuri, Chelsea S. Bahney, Nicole Ehrhart, Johnny Huard
Publikováno v:
Journal of orthopaedic research : official publication of the Orthopaedic Research SocietyREFERENCES.
Mesenchymal stem cells (MSCs) have been proven to promote tissue repair. However, concerns related to their clinical application and regulatory hurdles remain. Recent data has demonstrated the proregenerative secretome of MSCs can result in similar e
Autor:
Chi-Yi Lin, Xueqin Gao, Xiaodong Mu, Wanqun Chen, William S. Hambright, Ying Tang, Sudheer Ravuri, Polina Matre, Johnny Huard, Yan Cui, Ling Zhong, Bing Wang, Aiping Lu
Publikováno v:
Aging (Albany NY)
Duchenne Muscular Dystrophy (DMD) patients often suffer from both muscle wasting and osteoporosis. Our previous studies have revealed reduced regeneration potential in skeletal muscle and bone, concomitant with ectopic calcification of soft tissues i
Autor:
Kaitlyn E. Whitney, Haylie Lengel, Verena Oberlohr, John Weston Mitchell, William S. Hambright, Johnny Huard, Andrew Eck
Publikováno v:
Joint Function Preservation ISBN: 9783030829575
Joint Function Preservation
Joint Function Preservation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65a07ea311ad168cf23be27362fdbe52
https://doi.org/10.1007/978-3-030-82958-2_4
https://doi.org/10.1007/978-3-030-82958-2_4
Autor:
Yohei Kawakami, Laura J. Niedernhofer, Paul D. Robbins, Tomoyuki Matsumoto, Masahiro Kurosaka, Xiaodong Mu, Johnny Huard, Ryosuke Kuroda, William S. Hambright, Koji Takayama, Takashi Yurube, Aiping Lu, Freddie H. Fu, James H. Cummins
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Aging-related loss of adult stem cell function contributes to impaired tissue regeneration. Mice deficient in zinc metalloproteinase STE24 (Zmpste24−/−) exhibit premature age-related musculoskeletal pathologies similar to those observed in childr