Zobrazeno 1 - 10
of 28
pro vyhledávání: '"William S. Dodd"'
Autor:
William S. Dodd, Devan Patel, Dimitri Laurent, Brandon Lucke-Wold, Koji Hosaka, Richard D. Johnson, Nohra Chalouhi, Andrew A. Butler, Eduardo Candelario-Jalil, Brian L. Hoh
Publikováno v:
Frontiers in Stroke, Vol 3 (2024)
BackgroundSubarachnoid hemorrhage (SAH) is a life-threatening vascular condition without satisfactory treatment options. The secreted peptide adropin is highly expressed in the human brain and has neuroprotective effects in brain injury models, inclu
Externí odkaz:
https://doaj.org/article/378d02b99a864e8ca480c04d65843119
Autor:
Frederick J. Ashby, William S. Dodd, Emily W. Helm, Daniel Stribling, Lisa B. Spiryda, Coy D. Heldermon, Yuxing Xia
Publikováno v:
International Medical Education, Vol 2, Iss 3, Pp 161-174 (2023)
Background: Physician burnout is increasingly recognized as a problem in physician well-being and may negatively affect patient care outcomes. Burnout can begin at any point of training or practice, potentially as early as the first year of medical s
Externí odkaz:
https://doaj.org/article/11acb7b7252a454baaebc0f1ad06fb70
Autor:
Devan Patel, William S. Dodd, Brandon Lucke‐Wold, Muhammad Abdul Baker Chowdhury, Koji Hosaka, Brian L. Hoh
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 21 (2023)
Background Intracranial aneurysms (IAs) are more prevalent in women than men, and aneurysmal subarachnoid hemorrhage disproportionately affects postmenopausal women. These sex differences suggest estrogen protects against IA progression that can lead
Externí odkaz:
https://doaj.org/article/ee25e712f237488ba6c20c6415f02eed
Autor:
William S. Dodd, Eric J. Panther, Kevin Pierre, Jairo S. Hernandez, Devan Patel, Brandon Lucke-Wold
Publikováno v:
Trauma Care, Vol 2, Iss 4, Pp 510-522 (2022)
Traumatic brain injury (TBI) is a devastating event with severe long-term complications. TBI and its sequelae are one of the leading causes of death and disability in those under 50 years old. The full extent of secondary brain injury is still being
Externí odkaz:
https://doaj.org/article/6f29720480124f84b86de4f3f81e0460
Autor:
William S. Dodd, Coulter N. Small, Michael Goutnik, Dimitri Laurent, James Crossman, Kartik Motwani, Brandon Lucke‐Wold, Adam J. Polifka, Matthew Koch, Grzegorz Brzezicki, Brian L. Hoh, Nohra Chalouhi
Publikováno v:
Stroke: Vascular and Interventional Neurology, Vol 3, Iss 1 (2023)
Background Modern medicine necessitates the delivery of increasingly complex health care while minimizing cost. Transradial access (TRA) for neuroendovascular procedures is becoming more common as accumulating data demonstrate fewer complications, im
Externí odkaz:
https://doaj.org/article/725846bff91e42c9bc8e9a07c2442907
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-11 (2021)
Abstract Background The NLRP3 inflammasome is a critical mediator of several vascular diseases through positive regulation of proinflammatory pathways. In this study, we defined the role of NLRP3 in both the acute and delayed phases following subarac
Externí odkaz:
https://doaj.org/article/dc49f4eb97b14a6e89d742bf271f7299
Autor:
William S. Dodd, Dimitri Laurent, Aaron S. Dumont, David M. Hasan, Pascal M. Jabbour, Robert M. Starke, Koji Hosaka, Adam J. Polifka, Brian L. Hoh, Nohra Chalouhi
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 15 (2021)
Delayed cerebral ischemia is a major predictor of poor outcomes in patients who suffer subarachnoid hemorrhage. Treatment options are limited and often ineffective despite many years of investigation and clinical trials. Modern advances in basic scie
Externí odkaz:
https://doaj.org/article/10f3a1a3dc2243049e0a22c160cb2a0d
Autor:
Koji Hosaka, Brian L. Hoh, William S Dodd, Brandon Lucke-Wold, Kartik Motwani, Dimitri Laurent, Melanie Martinez
Publikováno v:
Curr Neurovasc Res
The correlation of neuroinflammation with the development of cerebral vasospasm following subarachnoid hemorrhage has been well documented in the literature; both clinical and preclinical. The exact mechanisms by which this process occurs, however, a
Publikováno v:
Biochem Biophys Res Commun
Background Cell-free heme-containing proteins mediate endothelial injury in a variety of disease states including subarachnoid hemorrhage and sepsis by increasing endothelial permeability. Inflammatory cells are also attracted to sites of vascular in
Publikováno v:
Neurosurgery. 69:70-71