Zobrazeno 1 - 10
of 42
pro vyhledávání: '"William S. Bowen"'
Autor:
Victor Hugo Canela, William S. Bowen, Ricardo Melo Ferreira, Farooq Syed, James E. Lingeman, Angela R. Sabo, Daria Barwinska, Seth Winfree, Blue B. Lake, Ying-Hua Cheng, Joseph P. Gaut, Michael Ferkowicz, Kaice A. LaFavers, Kun Zhang, Fredric L. Coe, Elaine Worcester, the Kidney Precision Medicine Project, Sanjay Jain, Michael T. Eadon, James C. Williams, Tarek M. El-Achkar
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Kidney stone disease causes significant morbidity and increases health care utilization. In this work, we decipher the cellular and molecular niche of the human renal papilla in patients with calcium oxalate (CaOx) stone disease and healthy
Externí odkaz:
https://doaj.org/article/9079daace87a49889ca16163b6717e46
Autor:
William S. Bowen, Abhishek K. Svrivastava, Lalit Batra, Hampartsoum Barsoumian, Haval Shirwan
Publikováno v:
Expert Review of Vaccines, Vol 17, Iss 3, Pp 207-215 (2018)
Introduction: Although much progress has been made in the last decade(s) toward development of effective cancer vaccines, there are still important obstacles to therapeutic successes. New generations of cancer vaccines will benefit from a combination
Externí odkaz:
https://doaj.org/article/93b04ad24d5944d792cc384cd29ca2e4
Autor:
Esma S. Yolcu, Haval Shirwan, Matthew B. Lawrenz, Lalit Batra, William S. Bowen, Amanda R. Pulsifer
Publikováno v:
Vaccine
Yersinia pestis is the causative agent of plague and is a re-emerging pathogen that also has the potential as a biological weapon, necessitating the development of a preventive vaccine. Despite intense efforts for the last several decades, there is c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdd8f175d1b6e8b4cf9fe20383c95798
https://doi.org/10.1016/j.vaccine.2019.07.103
https://doi.org/10.1016/j.vaccine.2019.07.103
Autor:
William S. Bowen, Pradeep Shrestha, Hong Zhao, Lalit Batra, Jorge G. Gomez-Gutierrez, Hampartsoum B. Barsoumian, Esma S. Yolcu, Haval Shirwan, Nejat K. Egilmez
Publikováno v:
Cancer Research. 79:783-794
Costimulation through 4-1BB (CD137) receptor generates robust CD8+ T-effector and memory responses. The only known ligand, 4-1BBL, is a trimeric transmembrane protein that has no costimulatory activity as a soluble molecule. Thus, agonistic antibodie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::968b9f7eaf7b399c0e9baa10513b20f7
https://doi.org/10.1158/0008-5472.can-18-2401
https://doi.org/10.1158/0008-5472.can-18-2401
Autor:
Haval Shirwan, Hampartsoum B. Barsoumian, Lalit Batra, Pradeep Shrestha, William S. Bowen, Hong Zhao, Nejat K. Egilmez, Jorge G. Gomez-Gutierrez, Esma S. Yolcu
Publikováno v:
Cancer Research. 79:4145-4145
Background: Costimulation through 4-1BB (CD137) receptor has been targeted for cancer immunotherapy using agonistic antibodies, which have been shown to cause liver toxicity in preclinical and clinical settings. We hypothesized that this might not be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25d1cc4e5971ebf0d29211b8696ad709
https://doi.org/10.1158/1538-7445.am2019-4145
https://doi.org/10.1158/1538-7445.am2019-4145
Autor:
Hampartsoum B, Barsoumian, Lalit, Batra, Pradeep, Shrestha, William S, Bowen, Hong, Zhao, Nejat K, Egilmez, Jorge G, Gomez-Gutierrez, Esma S, Yolcu, Haval, Shirwan
Publikováno v:
Cancer research. 79(4)
Costimulation through 4–1BB (CD137) receptor generates robust CD8(+) T effector and memory responses. The only known ligand, 4–1BBL, is a trimeric transmembrane protein that has no costimulatory activity as a soluble molecule. Thus, agonistic ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eeadf642c1af9cb7025808fd61185e6d
https://pubmed.ncbi.nlm.nih.gov/30770367
https://pubmed.ncbi.nlm.nih.gov/30770367
Autor:
Hampartsoum B. Barsoumian, Haval Shirwan, Lalit Batra, William S. Bowen, Abhishek K. Svrivastava
Publikováno v:
Expert review of vaccines. 17(3)
Although much progress has been made in the last decade(s) toward development of effective cancer vaccines, there are still important obstacles to therapeutic successes. New generations of cancer vaccines will benefit from a combination adjuvant appr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98381650062534b4eddf959914697940
https://pubmed.ncbi.nlm.nih.gov/29372660
https://pubmed.ncbi.nlm.nih.gov/29372660
Autor:
Lalit Batra, Hampartsoum B. Barsoumian, Pradeep Shrestha, Jenci L. Hawthorne, William S. Bowen, Hong Zhao, Nejat K. Egilmez, Jorge G. Gomez-Gutierrez, Haval Shirwan, Esma S. Yolcu
Publikováno v:
The Journal of Immunology. 202:71.6-71.6
Background CD137 immune checkpoint stimulator plays an important role in T cell responses and has been targeted for cancer immunotherapy using agonistic Abs with shown toxicity. We herein report that a novel oligomeric form of the CD137 ligand, SA-4-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70d760e6ed97d7e770e1754a5e817286
https://doi.org/10.4049/jimmunol.202.supp.71.6
https://doi.org/10.4049/jimmunol.202.supp.71.6
Publikováno v:
Transplantation. 102:S47
Materials and Methods A chimeric gene containing the extracellular domain of murine CD47 fused to a core streptavidin (SA) was constructed. SA-CD47 protein was produced in insect cells and purified using affinity chromatography. The function of SA-CD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15d2c44c15a117ed223de76bfae80e86
https://doi.org/10.1097/01.tp.0000542608.84915.b0
https://doi.org/10.1097/01.tp.0000542608.84915.b0
Autor:
Michael D. Hunckler, Kyle B. Woodward, Pradeep Shrestha, Jessica D. Weaver, Min Tan, William S. Bowen, Esma S. Yolcu, Andrés J. García, Maria M. Coronel, Devon M. Headen, Haval Shirwan
Publikováno v:
Transplantation. 102:S291
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba8d9807d74cb475d44a80e414610429
https://doi.org/10.1097/01.tp.0000542995.31760.b5
https://doi.org/10.1097/01.tp.0000542995.31760.b5