Zobrazeno 1 - 10
of 271
pro vyhledávání: '"William S. Hancock"'
Publikováno v:
Amino Acids. 51:1353-1363
Interferons are signaling proteins that belong to the large class of cytokines and human interferons which are classified based on the type of receptor interactions: type I, II and III. IFNα2b belongs to the type I interferon class with a major ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f1d5297034c958576ce485765660ef
https://doi.org/10.1007/s00726-019-02772-9
https://doi.org/10.1007/s00726-019-02772-9
Autor:
Roger Higdon, Jessie Kala, Devan Wilkins, Julia Fangfei Yan, Manveen K. Sethi, Liang Lin, Siqi Liu, Elizabeth Montague, Imre Janko, John Choiniere, Natali Kolker, William S. Hancock, Eugene Kolker, Susan Fanayan
Publikováno v:
Proteomes, Vol 5, Iss 1, p 5 (2017)
Medulloblastoma (MB) is the most common malignant pediatric brain tumor. Patient survival has remained largely the same for the past 20 years, with therapies causing significant health, cognitive, behavioral and developmental complications for those
Externí odkaz:
https://doaj.org/article/98c76ada1e1f48e199ff1afa975ddbf0
Autor:
Chaz Goodwine, Wu Sl, Catherine Bartlett Matthews, J. C. Love, Cvetkovic A, Nicholas J. Mozdzierz, Steven M. Timmick, Craig A. Mascarenhas, Kartik A. Shah, Kerry R. Love, Amos E. Lu, Alexandra D. Bonnyman, Nicholas Vecchiarello, William S. Hancock, Doherty W, Wang Ya, Richard D. Braatz, Clark Jj, Di Wu, Laura E. Crowell, Liu Y, Neil C. Dalvie, Steven M. Cramer, Liu D, Bradbury L, Brady, Noelle Colant, Alan Stockdale
Publikováno v:
Nature biotechnology
PMC
PMC
A benchtop system for protein synthesis achieves purity and potency comparable to those of marketed drugs. Conventional manufacturing of protein biopharmaceuticals in centralized, large-scale, single-product facilities is not well-suited to the agile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab40a9d79584eed8ae3e3868ba1e26f0
https://doi.org/10.1038/nbt.4262
https://doi.org/10.1038/nbt.4262
Autor:
William S Hancock
This highly illustrated volume will describe, through clear diagrams and concise text, how the most prescribed, as well as new medicines, work in the body for a broad range of diseases. By bringing this knowledge together in one place, we will seek t
Autor:
Di Wu, Shiaw-Lin Wu, Nicholas J. Mozdzierz, Kerry R. Love, J. Christopher Love, Yu Annie Wang, Jared R. Auclair, Yang Tang, William S. Hancock, Jeffrey N. Agar, Kartik A. Shah, Joseph P. Salisbury, Richa Sarin, Anna Fan Zhang
Publikováno v:
Analytical Chemistry. 89:12771-12777
With the advent of biosimilars to the U.S. market, it is important to have better analytical tools to ensure product quality from batch to batch. In addition, the recent popularity of using a continuous process for production of biopharmaceuticals, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e391c6c4b2e0c3eba3ca7ac2f650dc1b
https://doi.org/10.1021/acs.analchem.7b03026
https://doi.org/10.1021/acs.analchem.7b03026
Publikováno v:
Analytical Chemistry. 89:11036-11043
Influenza hemagglutinin is a surface glycoprotein related to virus invasion and host immune system response. Understanding site specific glycosylation of hemagglutinin will increase our knowledge about virus evolution and can improve the design and q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80f3958604f5318e2d62f12d33d7af89
https://doi.org/10.1021/acs.analchem.7b03025
https://doi.org/10.1021/acs.analchem.7b03025
Publikováno v:
Protein Purification Process Engineering ISBN: 9780203741733
Successful and rapid process development requires the availability of suitable analytical methods at all stages of the development cycle (see Tables 2 and 3). The methods should be selected first to ensure the identity, potency, and purity of the pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3b71ba2ebaeac8bfbaa99a549692e1a
https://doi.org/10.1201/9780203741733-2
https://doi.org/10.1201/9780203741733-2
Publikováno v:
Journal of Proteome Research. 15:3945-3950
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43832a1d18859055b73e42a43211911a
https://doi.org/10.1021/acs.jproteome.6b00803
https://doi.org/10.1021/acs.jproteome.6b00803
Autor:
Di Wu, William S. Hancock, Paul W. Barone, Wei Ouyang, Sung Hee Ko, Annie Yu Wang, Jongyoon Han
Publikováno v:
Analytical Chemistry. 88:9669-9677
Therapeutic proteins (TPs) are critical in modern medicine, yet shortage of TPs in disaster situations and remote areas remains a worldwide challenge. Manufacturing and real-time release of TPs on demand at the point-of-care is considered the key to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35f1fb40678dace6cbc6da587044c25d
https://doi.org/10.1021/acs.analchem.6b02517
https://doi.org/10.1021/acs.analchem.6b02517