Zobrazeno 1 - 10
of 163
pro vyhledávání: '"William S, Brooks"'
Autor:
Anna Hofmann, Lisa M. Häsler, Marius Lambert, Stephan A. Kaeser, Susanne Gräber-Sultan, Ulrike Obermüller, Elke Kuder-Buletta, Christian la Fougere, Christoph Laske, Jonathan Vöglein, Johannes Levin, Nick C. Fox, Natalie S. Ryan, Henrik Zetterberg, Jorge J. Llibre-Guerra, Richard J. Perrin, Laura Ibanez, Peter R. Schofield, William S. Brooks, Gregory S. Day, Martin R. Farlow, Ricardo F. Allegri, Patricio Chrem Mendez, Takeshi Ikeuchi, Kensaku Kasuga, Jae-Hong Lee, Jee Hoon Roh, Hiroshi Mori, Francisco Lopera, Randall J. Bateman, Eric McDade, Brian A. Gordon, Jasmeer P. Chhatwal, Mathias Jucker, Stephanie A. Schultz, Dominantly Inherited Alzheimer Network
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Disease-modifying therapies for Alzheimer’s disease (AD) are likely to be most beneficial when initiated in the presymptomatic phase. To track the benefit of such interventions, fluid biomarkers are of great importance, with neurofilament
Externí odkaz:
https://doaj.org/article/0a454b50306942c5b151db45a71682b3
Publikováno v:
MedEdPublish, Vol 14 (2024)
Disability is extremely common, and there is a need for high quality medical school curricula on working with persons with disabilities. The goal of disability training is to provide the proper knowledge and skills to address the unique needs of PWD,
Externí odkaz:
https://doaj.org/article/4c0b4ddaa177411398f259fe25aa72de
Autor:
Stephanie Doering, Austin McCullough, Brian A. Gordon, Charles D. Chen, Nicole McKay, Diana Hobbs, Sarah Keefe, Shaney Flores, Jalen Scott, Hunter Smith, Stephen Jarman, Kelley Jackson, Russ C. Hornbeck, Beau M. Ances, Chengjie Xiong, Andrew J. Aschenbrenner, Jason Hassenstab, Carlos Cruchaga, Alisha Daniels, Randall J. Bateman, John C. Morris, Tammie L.S. Benzinger, James M. Noble, Gregory S. Day, Neill R. Graff-Radford, Jonathan Voglein, Johannes Levin, Ricardo F. Allegri, Patricio Chrem Mendez, Ezequiel Surace, Sarah B. Berman, Snezana Ikonomovic, Neelesh K. Nadkarni, Francisco Lopera, Laura Ramirez, David Aguillon, Yudy Leon, Claudia Ramos, Diana Alzate, Ana Baena, Natalia Londono, Sonia Moreno, Mathias Jucker, Christoph Laske, Elke Kuder-Buletta, Susanne Graber-Sultan, Oliver Preische, Anna Hofmann, Takeshi Ikeuchi, Kensaku Kasuga, Yoshiki Niimi, Kenji Ishii, Michio Senda, Raquel Sanchez-Valle, Pedro Rosa-Neto, Nick C. Fox, Dave Cash, Jae-Hong Lee, Jee Hoon Roh, Stephen Salloway, Meghan C. Riddle, William Menard, Courtney Bodge, Mustafa Surti, Leonel Tadao Takada, Martin Farlow, Jasmeer P. Chhatwal, V.J. Sanchez-Gonzalez, Maribel Orozco-Barajas, Alison M. Goate, Alan E. Renton, Bianca T. Esposito, Celeste M. Karch, Jacob Marsh, Victoria Fernanadez, Anne M. Fagan, Gina Jerome, Elizabeth Herries, Jorge Llibre-Guerra, Allan I. Levey, Erik C.B. Johnson, Nicholas T. Seyfried, Peter R. Schofield, William S. Brooks, Jacob A. Bechara, Randall Bateman, Eric McDade, Richard J. Perrin, Erin E. Franklin, Tammie Benzinger, Allison Chen, Charles Chen, Nelly Friedrichsen, Brian Gordon, Nancy Hantler, Russ Hornbeck, Steve Jarman, Deborah Koudelis, Parinaz Massoumzadeh, Joyce Nicklaus, Christine Pulizos, Qing Wang, Sheetal Mishall, Edita Sabaredzovic, Emily Deng, Madison Candela, Peter Wang, Xiong Xu, Yan Li, Emily Gremminger, Yinjiao Ma, Ryan Bui, Ruijin Lu, Ralph Martins, Ana Luisa Sosa Ortiz, Laura Courtney, Hiroshi Mori, Charlene Supnet-Bell, Jinbin Xu, John Ringman, Nicolas Barthelemy, John Morris, Jennifer Smith
Publikováno v:
EBioMedicine, Vol 103, Iss , Pp 105080- (2024)
Summary: Background: Neuroimaging studies often quantify tau burden in standardized brain regions to assess Alzheimer disease (AD) progression. However, this method ignores another key biological process in which tau spreads to additional brain regio
Externí odkaz:
https://doaj.org/article/0b7b8db8958a47c9b99946f7b5107ddb
Autor:
Andrew J. Aschenbrenner, Jason Hassenstab, Guoqiao Wang, Yan Li, Chengjie Xiong, Eric McDade, David B. Clifford, Stephen Salloway, Martin Farlow, Roy Yaari, Eden Y. J. Cheng, Karen C. Holdridge, Catherine J. Mummery, Colin L. Masters, Ging-Yuek Hsiung, Ghulam Surti, Gregory S. Day, Sandra Weintraub, Lawrence S. Honig, James E. Galvin, John M. Ringman, William S. Brooks, Nick C. Fox, Peter J. Snyder, Kazushi Suzuki, Hiroyuki Shimada, Susanne Gräber, Randall J. Bateman
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Demonstrating a slowing in the rate of cognitive decline is a common outcome measure in clinical trials in Alzheimer’s disease (AD). Selection of cognitive endpoints typically includes modeling candidate outcome measures in the many, richly phenoty
Externí odkaz:
https://doaj.org/article/729c320574be4f4a868a3bad97db96d9
Autor:
Yi Su, Shaney Flores, Guoqiao Wang, Russ C. Hornbeck, Benjamin Speidel, Nelly Joseph‐Mathurin, Andrei G. Vlassenko, Brian A. Gordon, Robert A. Koeppe, William E. Klunk, Clifford R. Jack Jr., Martin R. Farlow, Stephen Salloway, Barbara J. Snider, Sarah B. Berman, Erik D. Roberson, Jared Brosch, Ivonne Jimenez‐Velazques, Christopher H. vanDyck, Douglas Galasko, Shauna H. Yuan, Suman Jayadev, Lawrence S. Honig, Serge Gauthier, Ging‐Yuek R. Hsiung, Mario Masellis, William S. Brooks, Michael Fulham, Roger Clarnette, Colin L. Masters, David Wallon, Didier Hannequin, Bruno Dubois, Jeremie Pariente, Raquel Sanchez‐Valle, Catherine Mummery, John M. Ringman, Michel Bottlaender, Gregory Klein, Smiljana Milosavljevic‐Ristic, Eric McDade, Chengjie Xiong, John C. Morris, Randall J. Bateman, Tammie L.S. Benzinger
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 11, Iss 1, Pp 180-190 (2019)
Abstract Introduction Quantitative in vivo measurement of brain amyloid burden is important for both research and clinical purposes. However, the existence of multiple imaging tracers presents challenges to the interpretation of such measurements. Th
Externí odkaz:
https://doaj.org/article/6e1734993f954447b3409ef075057895
Autor:
Ophir Keret, Adam M. Staffaroni, John M. Ringman, Yann Cobigo, Sheng‐Yang M. Goh, Amy Wolf, Isabel Elaine Allen, Stephen Salloway, Jasmeer Chhatwal, Adam M. Brickman, Dolly Reyes‐Dumeyer, Randal J. Bateman, Tammie L.S. Benzinger, John C. Morris, Beau M. Ances, Nelly Joseph‐Mathurin, Richard J. Perrin, Brian A. Gordon, Johannes Levin, Jonathan Vöglein, Mathias Jucker, Christian laFougère, Ralph N. Martins, Hamid R. Sohrabi, Kevin Taddei, Victor L. Villemagne, Peter R. Schofield, William S. Brooks, Michael Fulham, Colin L. Masters, Bernardino Ghetti, Andrew J. Saykin, Clifford R. Jack, Neill R. Graff‐Radford, Michael Weiner, David M. Cash, Ricardo F. Allegri, Patricio Chrem, Su Yi, Bruce L. Miller, Gil D. Rabinovici, Howard J. Rosen, Dominantly Inherited Alzheimer Network
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction Asymptomatic and mildly symptomatic dominantly inherited Alzheimer's disease mutation carriers (DIAD‐MC) are ideal candidates for preventative treatment trials aimed at delaying or preventing dementia onset. Brain atrophy is a
Externí odkaz:
https://doaj.org/article/90049bc6e3de456c9fce7e852de2612b
Autor:
Michele A. Haight, Ingrid Bahner, Andrea L. Belovich, Giulia Bonaminio, William S. Brooks, Cassie Chin, Shafik Habal, Nehad El-Sawi, Sandra B. Haudek, Uzoma Ikonne, Robert J. McAuley, Douglas McKell, Rachel Porter, Rebecca Rowe, Tracey A. H. Taylor, Thomas Thesen
Publikováno v:
Medical Science Educator. 33:311-315
Comparing cortical signatures of atrophy between late-onset and autosomal dominant Alzheimer disease
Autor:
Aylin Dincer, Brian A. Gordon, Amrita Hari-Raj, Sarah J. Keefe, Shaney Flores, Nicole S. McKay, Angela M. Paulick, Kristine E. Shady Lewis, Rebecca L. Feldman, Russ C. Hornbeck, Ricardo Allegri, Beau M. Ances, Sarah B. Berman, Adam M. Brickman, William S. Brooks, David M. Cash, Jasmeer P. Chhatwal, Martin R. Farlow, Christian la Fougère, Nick C. Fox, Michael J. Fulham, Clifford R. Jack, Jr., Nelly Joseph-Mathurin, Celeste M. Karch, Athene Lee, Johannes Levin, Colin L. Masters, Eric M. McDade, Hwamee Oh, Richard J. Perrin, Cyrus Raji, Stephen P. Salloway, Peter R. Schofield, Yi Su, Victor L. Villemagne, Qing Wang, Michael W. Weiner, Chengjie Xiong, Igor Yakushev, John C. Morris, Randall J. Bateman, Tammie L.S. Benzinger
Publikováno v:
NeuroImage: Clinical, Vol 28, Iss , Pp 102491- (2020)
Defining a signature of cortical regions of interest preferentially affected by Alzheimer disease (AD) pathology may offer improved sensitivity to early AD compared to hippocampal volume or mesial temporal lobe alone. Since late-onset Alzheimer disea
Externí odkaz:
https://doaj.org/article/205e5a7f405a4395a614a02bce747193
Autor:
Ashley Parish, Cathy Carver, Donald H. Lein, Elizabeth Wylie, Will A. Byrd, Obadiah J. Pirlo, William S. Brooks
Publikováno v:
Teaching and Learning in Medicine. :1-15
Publikováno v:
Anatomical Sciences Education.