Zobrazeno 1 - 10
of 20
pro vyhledávání: '"William Rounds"'
Autor:
Benjamin Greenberg, Lindsay G. Cowell, Inimary T. Toby, Jared Ostmeyer, William Rounds, Nancy L. Monson, Scott Christley
Publikováno v:
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-10 (2017)
BMC bioinformatics, vol 18, iss 1
BMC Bioinformatics
BMC bioinformatics, vol 18, iss 1
BMC Bioinformatics
Background Deep sequencing of lymphocyte receptor repertoires has made it possible to comprehensively profile the clonal composition of lymphocyte populations. This opens the door for novel approaches to diagnose and prognosticate diseases with a dri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca3a725346e8776b0595d69ec0cf523
http://link.springer.com/article/10.1186/s12859-017-1814-6
http://link.springer.com/article/10.1186/s12859-017-1814-6
Autor:
Mark Woodhall, Nancy L. Monson, Ann M. Stowe, Ann J. Ligocki, Alyssa A. Guzman, Benjamin Greenberg, Sara J. Ireland, Patrick C. Wilson, Patrick Waters, William Rounds, Jordan Johnson, Ding Chen, Denise M.O. Ramirez, Jacqueline R. Rivas, Joseph Lim, Rati Chkheidze, Charles L. White, Eric Meffre, Lindsay G. Cowell
Plasmablasts are a highly differentiated, antibody secreting B cell subset whose prevalence correlates with disease activity in Multiple Sclerosis (MS). For most patients experiencing partial transverse myelitis (PTM), plasmablasts are elevated in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e118d92dd01bca7f6bb6933e6792fda
https://doi.org/10.1007/s00401-016-1627-0
https://doi.org/10.1007/s00401-016-1627-0
Autor:
Carolina Ionete, Nancy L. Monson, Steven Vernino, Carlos A. Pardo, Douglas Bigwood, Benjamin Greenberg, Eric M. Eastman, Eddie Salinas, Tom B. Wilks, Mikhail K. Levin, Lindsay G. Cowell, William Rounds, Ann J. Ligocki
Publikováno v:
Gene, vol 572, iss 2
Background We have previously demonstrated that cerebrospinal fluid-derived B cells from early relapsing–remitting multiple sclerosis (RRMS) patients that express a VH4 gene accumulate specific replacement mutations. These mutations can be quantifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::882c3b2bdd921964c2981085a260630e
https://doi.org/10.1016/j.gene.2015.07.011
https://doi.org/10.1016/j.gene.2015.07.011
Autor:
John M. Fonner, Nancy L. Monson, Mikhail K. Levin, Walter Scarborough, Inimary T. Toby, William Rounds, Lindsay G. Cowell, Scott Christley, Richard H. Scheuermann, Florian Rubelt
Publikováno v:
BMC bioinformatics, vol 18, iss 1
BMC Bioinformatics
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-5 (2017)
BMC Bioinformatics
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-5 (2017)
Background Pre-processing of high-throughput sequencing data for immune repertoire profiling is essential to insure high quality input for downstream analysis. VDJPipe is a flexible, high-performance tool that can perform multiple pre-processing task
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0ff157eb86a01249e01e6bf4cc57052
https://escholarship.org/uc/item/5pz4g4w3
https://escholarship.org/uc/item/5pz4g4w3
Autor:
Inimary T. Toby, John M. Fonner, Nancy L. Monson, Mikhail K. Levin, Aaron M. Rosenfeld, Namita Gupta, Scott Christley, Sanchita Bhattacharya, Florian Rubelt, Mohamed Uduman, Adam Buntzman, Brian Corrie, Nishanth Marthandan, William Rounds, Edward Salinas, Uri Hershberg, Jason A. Vander Heiden, Jamie K. Scott, Lindsay G. Cowell, Steven H. Kleinstein, Walter Scarborough, Richard H. Scheuermann, Felix Breden
Publikováno v:
BMC bioinformatics, vol 17, iss Suppl 13
BMC Bioinformatics
BMC Bioinformatics
The genes that produce antibodies and the immune receptors expressed on lymphocytes are not germline encoded; rather, they are somatically generated in each developing lymphocyte by a process called V(D)J recombination, which assembles specific, inde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e185ba7fff877ef227aaffad019a898
https://escholarship.org/uc/item/1288x9gb
https://escholarship.org/uc/item/1288x9gb
Autor:
Melania Spadaro, Alyssa A. Guzman, William H. Robinson, Charles L. White, Paul Henson, Ding Chen, Lauren J. Lahey, Nancy L. Monson, Edgar Meinl, Min Li, E. Sally Ward, Ann J. Ligocki, Benjamin Greenberg, William Rounds, Donna Graves, Elliot M. Frohman, Jacqueline R. Rivas, Ann M. Stowe
Publikováno v:
ASN NEURO
ASN neuro, vol 7, iss 5
ASN Neuro, Vol 7 (2015)
ASN neuro, vol 7, iss 5
ASN Neuro, Vol 7 (2015)
* These authors contributed equally to the work in this manuscript. We have previously identified a distinct class of antibodies expressed by B cells in the cerebrospinal fluid (CSF) of early and established relapsing remitting multiple sclerosis (RR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a45af33f3a22b2715e4c3aa04125095
http://europepmc.org/articles/PMC4710131
http://europepmc.org/articles/PMC4710131
Autor:
Sarah J. Pfau, Peter A. Combs, Carmen Young, J. Scott Breunig, Yufei Liu, Sandhya Sinha, Maitreya J. Dunham, Rosa M. Mendoza, Max V. Staller, Aaron Hoisos, Richa Gawande, Konrad J. Karczewski, Julia Liu, Jie Yuan, Erin C. Bush, Namita Bisaria, Christian Millian, Hugo Arellano, Daniel Gadala-Maria, Samuel Grossberg, Evgeni M. Frenkel, William Rounds, Christopher A. Crutchfield, Alicia P. Hayes, David S. Glass, Walter Chen, Joy Agee, Chris DeSevo, Matthew S. Rich, Jenny Hsi, Philip Stern, Trevor Martin, Sanford J. Silverman, Sandeep Raj, Mina L Kojima, Christopher D. Doucette, Matthew Salesi, Sachi Inukai, Samuel S. Freeman, Olga G. Troyanskaya, Anita Gupta, David Botstein, Juan R. Alvarez-Dominguez, Xiaobo Ke, Cameron Myhrvold, Peter Fellowes, Manuel Llinás, Rajani Sharma, John J. Clore, Maxwell Weidmann, Amy A. Caudy, Coleen T. Murphy, Patrick H. Bradley, Christina Hansen, Yue Jia, David A. Cappel, Joseph Rokicki, Olukunle O. Demuren, Samuel Leachman, Daniel R. Barrett, Hanlin Tang, Anna Liebowitz, Yuanfang Guan, Cynthia Bauerle, Jose Mena, Michael Salazar, Cara Singer, Sharon Weeks, Ashley R. Wolf, Megan N. McClean, Emily J. Capra, Latanya Hammonds-Odie, Daniel S. Lieber, Yu-Han Huang Hsu
Publikováno v:
Genetics
Whole-genome sequencing, particularly in fungi, has progressed at a tremendous rate. More difficult, however, is experimental testing of the inferences about gene function that can be drawn from comparative sequence analysis alone. We present a genom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a8e75cea2960982b0bbf0c60bfe6de
https://pubmed.ncbi.nlm.nih.gov/23852385
https://pubmed.ncbi.nlm.nih.gov/23852385
Autor:
Nancy L. Monson, William Rounds, Ding Chen, C. Munro Cullum, Ann M. Stowe, Benjamin Greenberg, Ryan M. Huebinger, Ann J. Ligocki, Min Li, Rong Zhang, Sara J. Ireland
Publikováno v:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, vol 34, iss 1
Alzheimer's disease (AD) is a progressive, neurodegenerative disease that may involve inflammatory responses in the central nervous system (CNS). Our objective was to determine whether patients with amnestic mild cognitive impairment (aMCI), a precli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54b62cdf27f7bf0a2e4b920eafe168ad
https://pubmed.ncbi.nlm.nih.gov/24149932
https://pubmed.ncbi.nlm.nih.gov/24149932
Autor:
Elizabeth M. Cameron, Elliot M. Frohman, Christopher T. Harp, Steven Vernino, Lindsay G. Cowell, Ann J. Ligocki, Benjamin Greenberg, William Rounds, Ardith Courtney, Nancy L. Monson
Patients with the autoimmune disease multiple sclerosis (MS) typically present with the clinically isolated syndromes (CIS) transverse myelitis (TM) or optic neuritis (ON). B-cell disturbances have been well documented in patients with MS and CIS pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::380f6bdc8f557f176a58a38135aecb9d
https://europepmc.org/articles/PMC4326094/
https://europepmc.org/articles/PMC4326094/
Autor:
Nancy Monson, Jacqueline Rivas, Sara Ireland, William Rounds, Ann Ligocki, Lisha Ma, Elliot Frohman, Benjamin Greenberg, Lindsay G Cowell, Ann Marie Stowe
Publikováno v:
The Journal of Immunology. 196:124.44-124.44
My lab’s recent work has led to the discovery that antibodies expressed by memory B cells in the cerebrospinal fluid (CSF) of patients with Multiple Sclerosis recognize neurons and astrocytes in the brain. Genetic analysis further revealed that onl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ca59f7a188da238004e48f245f32b2a
https://doi.org/10.4049/jimmunol.196.supp.124.44
https://doi.org/10.4049/jimmunol.196.supp.124.44