Zobrazeno 1 - 10
of 312
pro vyhledávání: '"William Richardson"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Decreased myocardial capillary density has been reported as an important histopathological feature associated with various heart disorders. Quantitative assessment of cardiac capillarization typically involves double immunostaining of cardio
Externí odkaz:
https://doaj.org/article/ecabc092c99f4f13b6157917d5125f20
Publikováno v:
European Journal of Histochemistry, Vol 67, Iss 4 (2023)
Autofluorescence (AF) poses challenges for detecting proteins of interest in situ when employing immunofluorescence (IF) microscopy. This interference is particularly pronounced in strongly autofluorescent tissues such as myocardium, where tissue AF
Externí odkaz:
https://doaj.org/article/4691f1c272bb4e76b046bf7ed9854779
Autor:
Anna Castano, Margaux Silvestre, Carrow I Wells, Jennifer L Sanderson, Carla A Ferrer, Han Wee Ong, Yi Lang, William Richardson, Josie A Silvaroli, Frances M Bashore, Jeffery L Smith, Isabelle M Genereux, Kelvin Dempster, David H Drewry, Navlot S Pabla, Alex N Bullock, Tim A Benke, Sila K Ultanir, Alison D Axtman
Publikováno v:
eLife, Vol 12 (2023)
Pathological loss-of-function mutations in cyclin-dependent kinase-like 5 (CDKL5) cause CDKL5 deficiency disorder (CDD), a rare and severe neurodevelopmental disorder associated with severe and medically refractory early-life epilepsy, motor, cogniti
Externí odkaz:
https://doaj.org/article/1bf476386b1149818536f2b15c6067c9
Autor:
Mario Figueroa, MD, SarahRose Hall, BS, Victoria Mattia, BS, Alex Mendoza, BS, Adam Brown, BS, Ying Xiong, PhD, Rupak Mukherjee, PhD, Jeffrey A. Jones, PhD, William Richardson, PhD, Jean Marie Ruddy, MD
Publikováno v:
JVS - Vascular Science, Vol 4, Iss , Pp 100124- (2023)
Objective: The objective of this investigation was to demonstrate that in vivo induction of hypertension (HTN) and in vitro cyclic stretch of aortic vascular smooth muscle cells (VSMCs) can cause serum and glucocorticoid-inducible kinase (SGK-1)-depe
Externí odkaz:
https://doaj.org/article/2fe44dd45d2e4d63aced5615d4a280fb
Publikováno v:
IUCrJ, Vol 8, Iss 5, Pp 823-832 (2021)
Transcription factors are the primary regulators of gene expression and recognize specific DNA sequences under diverse physiological conditions. Although they are vital for many important cellular processes, it remains unclear when and how transcript
Externí odkaz:
https://doaj.org/article/ba293b1fee3043e3a81a509a24023778
Publikováno v:
Interdisciplinary Neurosurgery, Vol 23, Iss , Pp 101024- (2021)
Prostate cancer (PCa) metastasis to the brain is rare. When it does metastasize to the brain, it typically presents as a dural-based lesion. Generally, intraparenchymal metastasis indicates diffuse disease, which often carries a poor prognosis, and i
Externí odkaz:
https://doaj.org/article/d9cb6a87984544488decbb84b7407e0f
Autor:
Fadi Soukarieh, Ruiling Liu, Manuel Romero, Shaun N. Roberston, William Richardson, Simone Lucanto, Eduard Vico Oton, Naim Ruhul Qudus, Alaa Mashabi, Scott Grossman, Sadiqur Ali, Tomás Sou, Irena Kukavica-Ibrulj, Roger C. Levesque, Christel A. S. Bergström, Nigel Halliday, Shailesh N. Mistry, Jonas Emsley, Stephan Heeb, Paul Williams, Miguel Cámara, Michael J. Stocks
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
Current treatments for Pseudomonas aeruginosa infections are becoming less effective because of the increasing rates of multi-antibiotic resistance. Pharmacological targeting of virulence through inhibition of quorum sensing (QS) dependent virulence
Externí odkaz:
https://doaj.org/article/2028c900e1c64f45a368b4dc67692ee3
Publikováno v:
Remote Sensing, Vol 13, Iss 20, p 4028 (2021)
Riparian and ground-water dependent ecosystems found in the Great Basin of North America are heavily utilized by livestock and wildlife throughout the year. Due to this constant pressure, grazing can be a major influence on many groundwater dependent
Externí odkaz:
https://doaj.org/article/ade024a0825e49b1a4374075ca1482fe
Publikováno v:
Reports, Vol 2, Iss 2, p 14 (2019)
Dural Arteriovenous Fistulas (dAVF) are pathological shunts that are often idiopathic in presentation. However, it is reported that many patients presenting with dAVF have past medical histories notable for surgeries, hypercoagulation disorders, infe
Externí odkaz:
https://doaj.org/article/775981ef580543aca4d84eb9c0937103
Autor:
Araceli G Castillo, Barbara G Mellone, Janet F Partridge, William Richardson, Georgina L Hamilton, Robin C Allshire, Alison L Pidoux
Publikováno v:
PLoS Genetics, Vol 3, Iss 7, p e121 (2007)
The histone H3 variant CENP-A assembles into chromatin exclusively at centromeres. The process of CENP-A chromatin assembly is epigenetically regulated. Fission yeast centromeres are composed of a central kinetochore domain on which CENP-A chromatin
Externí odkaz:
https://doaj.org/article/2201ef58a3f241cab67fe5dd1c5c855f