Zobrazeno 1 - 10
of 85
pro vyhledávání: '"William R. Tyor"'
Autor:
Christina Gavegnano, Woldeab B. Haile, Selwyn Hurwitz, Sijia Tao, Yong Jiang, Raymond F. Schinazi, William R. Tyor
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-12 (2019)
Abstract Background Since HIV-associated neurocognitive disorders (HANDs) occur in up to half of HIV-positive individuals, even with combined antiretroviral therapy (cART), adjunctive therapies are needed. Chronic CNS inflammation contributes to HAND
Externí odkaz:
https://doaj.org/article/4a86d90c74e947349cad25d881f8714d
Autor:
William T. Hu, Jennifer Christina Howell, Tugba Ozturk, Umesh Gangishetti, Alexander L. Kollhoff, Jaime M. Hatcher-Martin, Albert M. Anderson, William R. Tyor
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Inflammation is a common process involved in aging, multiple sclerosis (MS), and age-related neurodegenerative disorders such as Alzheimer's disease (AD) and Parkinson's disease (PD), but there is limited evidence for the effects of aging on inflamma
Externí odkaz:
https://doaj.org/article/546ac5ea5dc541218269c0a68915eb60
Autor:
Woldeab B. Haile, Christina Gavegnano, Sijia Tao, Yong Jiang, Raymond F. Schinazi, William R. Tyor
Publikováno v:
Neurobiology of Disease, Vol 92, Iss , Pp 137-143 (2016)
A hallmark of persistent HIV-1 infection in the central nervous system is increased activation of mononuclear phagocytes and surrounding astrogliosis, conferring persistent HIV-induced inflammation. This inflammation is believed to result in neuronal
Externí odkaz:
https://doaj.org/article/da70ac2044b84b39a6d4ebe81a3bbf5f
Publikováno v:
Journal of the International AIDS Society, Vol 19, Iss 1, Pp n/a-n/a (2016)
Externí odkaz:
https://doaj.org/article/d793b283e60641d2adcab22c06cc6206
Autor:
Christina Gavegnano, Selwyn J. Hurwitz, James J. Kohler, Raj Koneru, William R. Tyor, Raymond F. Schinazi, Woldeab B. Haile
Publikováno v:
J Neurovirol
Despite combined antiretroviral therapy (cART), HIV infection in the CNS persists with reported increases in activation of macrophages (MΦ), microglia, and surrounding astrocytes/neurons, conferring HIV-induced inflammation. Chronic inflammation res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd48af7583332ce1a61ee533cdbc4414
https://doi.org/10.1007/s13365-020-00842-3
https://doi.org/10.1007/s13365-020-00842-3
Publikováno v:
Journal of Investigative Medicine. 68:321-330
Although Multiple Sclerosis is the most common central nervous system (CNS) inflammatory demyelinating disorder, other CNS inflammatory disorders should be included as diagnostic considerations. Neuromyelitis Optica Spectrum Disorder (NMOSD) and myel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4847bf64c9fd2cc624a383c05d54a887
https://doi.org/10.1136/jim-2019-001126
https://doi.org/10.1136/jim-2019-001126
Autor:
Raymond F. Schinazi, Christina Gavegnano, William R. Tyor, Yong Jiang, Selwyn J. Hurwitz, Sijia Tao, Woldeab B. Haile
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-12 (2019)
Journal of Neuroinflammation
Journal of Neuroinflammation
BackgroundSince HIV-associated neurocognitive disorders (HANDs) occur in up to half of HIV-positive individuals, even with combined antiretroviral therapy (cART), adjunctive therapies are needed. Chronic CNS inflammation contributes to HAND and HIV e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0054cb09ef9c08050d6439fc7ed797d
http://link.springer.com/article/10.1186/s12974-019-1565-6
http://link.springer.com/article/10.1186/s12974-019-1565-6
Publikováno v:
J Neurovirol
HIV-associated neurocognitive disorders (HAND) continue to affect a large proportion of persons living with HIV despite effective viral suppression with combined antiretroviral therapy (cART). Importantly, milder versions of HAND have become more pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::862d5dc169fdab04067091f20b8e3eb0
https://doi.org/10.1007/s13365-019-00735-0
https://doi.org/10.1007/s13365-019-00735-0
Autor:
Deborah Molehin, Bum-Yong Kang, Justin M. Smith, Sonia C. Flores, Laurence Huang, Roy L. Sutliff, Cari F. Kessing, Kevin Pruitt, Edgar G. Martinez, Edu B Suárez-Martínez, Bryan McNair, Kaiser M. Bijli, Sushma K. Cribbs, Laura Pumarejo-Gomez, Priscilla Y. Hsue, Brandy E. Wade, Sharilyn Almodovar, David M. Guidot, Kristi M. Porter, William R. Tyor, Ethan A. Salazar, Robert Alexis Lopez-Astacio, Jaritza Perez Hernandez
Publikováno v:
Scientific Reports
Scientific reports, vol 10, iss 1
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific reports, vol 10, iss 1
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Pulmonary Arterial Hypertension (PAH) is overrepresented in People Living with Human Immunodeficiency Virus (PLWH). HIV protein gp120 plays a key role in the pathogenesis of HIV-PAH. Genetic changes in HIV gp120 determine viral interactions with chem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0448f27e10d19cf7422129d34401b7e8
http://europepmc.org/articles/PMC7366722
http://europepmc.org/articles/PMC7366722
Autor:
Drenna Waldrop-Valverde, Jeffrey L. Lennox, Mark J. Mulligan, William R. Tyor, Albert M. Anderson, Scott Letendre
Publikováno v:
Clinical Infectious Diseases. 67:137-140
New tools are needed to understand human immunodeficiency virus central nervous system involvement. Testing 15 cerebrospinal fluid (CSF) samples for p24 antigen, using a high-sensitivity assay, we found a strong correlation trend between CSF p24 conc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81e5994ab0c21cba941f543b3bd86b04
https://doi.org/10.1093/cid/ciy056
https://doi.org/10.1093/cid/ciy056