Zobrazeno 1 - 10
of 167
pro vyhledávání: '"William R. Schafer"'
Autor:
Isabel Beets, Sven Zels, Elke Vandewyer, Jonas Demeulemeester, Jelle Caers, Esra Baytemur, Amy Courtney, Luca Golinelli, İlayda Hasakioğulları, William R. Schafer, Petra E. Vértes, Olivier Mirabeau, Liliane Schoofs
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113058- (2023)
Summary: Neuropeptides and peptide hormones are ancient, widespread signaling molecules that underpin almost all brain functions. They constitute a broad ligand-receptor network, mainly by binding to G protein-coupled receptors (GPCRs). However, the
Externí odkaz:
https://doaj.org/article/443e8531c5bd43708644a2c6199b3654
Autor:
Michael K. Fasseas, Manish Grover, Florence Drury, Clara L. Essmann, Eva Kaulich, William R. Schafer, Michalis Barkoulas
Publikováno v:
Cell Reports, Vol 34, Iss 2, Pp 108604- (2021)
Summary: Understanding how animals detect and respond to pathogen threats is central to dissecting mechanisms of host immunity. The oomycetes represent a diverse eukaryotic group infecting various hosts from nematodes to humans. We have previously sh
Externí odkaz:
https://doaj.org/article/26ea6fa6476e4f6fae738f84dd54b2fe
Autor:
Arnaud P. J. Giese, Yi-Quan Tang, Ghanshyam P. Sinha, Michael R. Bowl, Adam C. Goldring, Andrew Parker, Mary J. Freeman, Steve D. M. Brown, Saima Riazuddin, Robert Fettiplace, William R. Schafer, Gregory I. Frolenkov, Zubair M. Ahmed
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Inner ear hair cells detect sound through deflection of stereocilia that harbor mechanically-gated channels. Here the authors show that protein responsible for Usher syndrome, CIB2, interacts with these channels and is essential for their function an
Externí odkaz:
https://doaj.org/article/65c3629626804bdea9661937eb27fcb2
Autor:
Lola Hostettler, Laura Grundy, Stéphanie Käser-Pébernard, Chantal Wicky, William R. Schafer, Dominique A. Glauser
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 2, Pp 607-615 (2017)
The Green Fluorescent Protein (GFP) has been tremendously useful in investigating cell architecture, protein localization, and protein function. Recent developments in transgenesis and genome editing methods now enable working with fewer transgene co
Externí odkaz:
https://doaj.org/article/214818759a804563a31d41e986db4b7f
Autor:
Eva Kaulich, Trae Carroll, Brian D Ackley, Yi-Quan Tang, Iris Hardege, Keith Nehrke, William R Schafer, Denise S Walker
Publikováno v:
eLife, Vol 11 (2022)
Biological clocks are fundamental to an organism’s health, controlling periodicity of behaviour and metabolism. Here, we identify two acid-sensing ion channels, with very different proton sensing properties, and describe their role in an ultradian
Externí odkaz:
https://doaj.org/article/460f7d81553148fd9ae4b9cbd221dbb6
Autor:
Denise S Walker, William R Schafer
Publikováno v:
eLife, Vol 9 (2020)
Mechanosensation is central to a wide range of functions, including tactile and pain perception, hearing, proprioception, and control of blood pressure, but identifying the molecules underlying mechanotransduction has proved challenging. In Caenorhab
Externí odkaz:
https://doaj.org/article/44478cf4cf7f4e91918984d88667b393
Autor:
Ana P Gómez‐Escribano, Carlos Mora‐Martínez, Marta Roca, Denise S Walker, Joaquín Panadero, Maria D Sequedo, Ratni Saini, Hans‐Joachim Knölker, Jose Blanca, Juan Burguera, Agustin Lahoz, Joaquin Cañizares, José M Millán, Nick O Burton, William R Schafer, Rafael P Vázquez‐Manrique
Publikováno v:
EMBO reports.
Fast cholinergic neurotransmission is mediated by acetylcholine-gated ion channels; in particular, excitatory nicotinic acetylcholine receptors play well established roles in virtually all nervous systems. Acetylcholine-gated inhibitory channels have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eab03f6b958226ebdd8230cd9b34726
https://lirias.kuleuven.be/handle/20.500.12942/713829
https://lirias.kuleuven.be/handle/20.500.12942/713829
Autor:
Isabel Beets, Sven Zels, Elke Vandewyer, Jonas Demeulemeester, Jelle Caers, Esra Baytemur, William R. Schafer, Petra E. Vértes, Olivier Mirabeau, Liliane Schoofs
SummaryNeuropeptides are ancient, widespread signaling molecules that underpin almost all brain functions. They constitute a broad ligand-receptor network, mainly by binding to G protein-coupled receptors (GPCRs). However, the organization of the pep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c56030b3be3cb56c0dd75bb794ce7f54
https://doi.org/10.1101/2022.10.30.514428
https://doi.org/10.1101/2022.10.30.514428
Autor:
Lidia Ripoll-Sánchez, Jan Watteyne, HaoSheng Sun, Robert Fernandez, Seth R Taylor, Alexis Weinreb, Mark Hammarlund, David M Miller, Oliver Hobert, Isabel Beets, Petra E Vértes, William R Schafer
SummaryEfforts are currently ongoing to map synaptic wiring diagrams or connectomes in order to understand the neural basis of brain function. However, chemical synapses represent only one type of functionally important neuronal connection; in partic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36bdcc3c8c907faa314f04386a844624
https://doi.org/10.1101/2022.10.30.514396
https://doi.org/10.1101/2022.10.30.514396