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pro vyhledávání: '"William R. Porter"'
Statistical models are described for processing data obtained in accelerated predictive stability studies. The impact of data censoring and rounding on the accuracy and precision of shelf-life predictions obtained using different data processing meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6edecb94a34856aa212946c2deded154
https://doi.org/10.1016/b978-0-12-802786-8.00006-1
https://doi.org/10.1016/b978-0-12-802786-8.00006-1
Autor:
Anjali Agrawal, Stan Altan, Steven W. Baertschi, Chandan Bhugra, Ricardo Borjas, John Campbell, Dana Carabillo, Juan Chen, Lilan H. Chen, Donald Clancy, Elise Clement, Stephen T. Colgan, David Curran, Gena Dalziel, Mayur Dudhedia, Sudharsan Dwaraknath, Anita L. Freed, Paul Gerst, Michael Hawley, Evan M. Hetrick, Cherokee S. Hoaglund Hyzer, Gordon Hutton, Madhuri Jerfy, Satish Kamath, Ammar Khawam, Todd Lewis, Hanlin Li, Julie Lippke, Bruce C. MacDonald, Llurellyn Malcolm, Keith Masse, Tony Mazzeo, Andrew P. Monahan, Ewa Nauka, Rachel Orr, Brian W. Pack, Jeegna Patel-Jones, Jackson D. Pellett, William R. Porter, Fenghe Qiu, Jeffrey C. Roberts, Samantha Rusk, Kevin O. Ryan, Kevin Ryan, Robert Schwabe, Garry Scrivens, Ashish Soman, Jon T. Swanson, Zhixin Jessica Tan, Martyn Ticehurst, Robert J. Timpano, Bryan S. Wicks, Zeena Williams, Chad N. Wolfe, Gavin Wood, Zufan Steven Wu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddf3d76a1a8cc8978d2bef65c0f977b9
https://doi.org/10.1016/b978-0-12-802786-8.09988-5
https://doi.org/10.1016/b978-0-12-802786-8.09988-5
Publisher Summary This chapter discusses the basic treatments of drug degradation studies, including kinetics, pathways, important factors, and typical practices for assessing both chemical and physical stability of pharmaceutical compounds. Chemical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff641aab496e89ca5e0db5f5c3e59aab
https://doi.org/10.1016/b978-0-12-802447-8.00005-4
https://doi.org/10.1016/b978-0-12-802447-8.00005-4
Autor:
William R. Porter
Publikováno v:
Journal of Computer-Aided Molecular Design. 24:553-573
The anticoagulant drug warfarin, normally administered as the racemate, can exist in solution in potentially as many as 40 topologically distinct tautomeric forms. Only 11 of these forms for each enantiomer can be distinguished by selected computatio
Autor:
Kenneth M. Gleason, Wolfgang Fraunhofer, Donghua (Alan) Zhu, William R. Porter, Yi Gao, Michelle A. Long
Publikováno v:
Thermochimica Acta. 499:1-7
The thermally induced irreversible aggregation of a monoclonal antibody in different pH buffers was investigated using different techniques such as micro-differential scanning calorimetry (micro-DSC), size exclusion HPLC (SEC) and isothermal microcal
Publikováno v:
European Journal of Pharmaceutical Sciences. 4:109-116
Zileuton (ABT-077) is a 5-lipoxygenase inhibitor with poor aqueous solubility. Using an extreme vertices experimental design and an empirical response surface analysis, both the solubility and pseudo-first-order degradation rate constants of zileuton
Autor:
William R. Porter
Publikováno v:
Analytical chemistry. 55(13)
Autor:
Fadwa Al-Taher, Lucia E. Anelich, Kalapanda M. Appaiah, Alejandro Ariosti, Janis Baines, Gustavo V. Barbosa-Canovas, Daniela Bermúdez-Aguirre, Christine E. Boisrobert, Hans Bouwmeester, Adelia C. Bovell-Benjamin, Paul Brent, Julie Larson Bricher, Elaine Bromfield, Frank F. Busta, Martin Cole, Pamela L. Coleman, Firouz Darroudi, Thibaut Dubois, Veronika Ehrlich, Anthony J. Fontana, Neal D. Fortin, Tracy Hambridge, Jaap C. Hanekamp, Vincent Hegarty, Heinz-Dieter Isengard, Lauren S. Jackson, Edward Jansson, Frans W.H. Kampers, Larry Keener, Ji Yeon Kim, Siegfried Knasmüller, Gisela Kopper, Jan H.J.M. Kwakman, Oran Kwon, Huub L.M. Lelieveld, Rebeca López-García, Volker Mersch-Sundermann, David Miles, Carmen Moraru, Sangsuk Oh, William R. Porter, Margherita Poto, V. Prakash, Keith C. Richardson, Syed S.H. Rizvi, Vijay D. Sattigeri, Bert Schwitters, Mun-Gi Sohn, Glenn Stanley, Cynthia M. Stewart, Juanjuan Sun, John G. Surak, Elizabeth A. Szabo, Martinus AJS (Tiny) van Boekel, Bernd van der Meulen, Mandyam C. Varadaraj, Yuriy Vasilyev, Axelle Wuillot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ca46ee0a43fd884e7a0ff34299c3a5c
https://doi.org/10.1016/b978-0-12-374845-4.00026-6
https://doi.org/10.1016/b978-0-12-374845-4.00026-6
Autor:
William R. Porter
Publisher Summary There are only three kinds of mathematical data: nominal, ordinal, and numerical. For each type of data different statistical techniques and methods of evaluation have been devised. Nominal data are obtained by conducting a census o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b26081ab6c56ca0fb84ae6eae173689f
https://doi.org/10.1016/b978-0-444-53242-8.00010-2
https://doi.org/10.1016/b978-0-444-53242-8.00010-2