Zobrazeno 1 - 10
of 14
pro vyhledávání: '"William R. P. Denault"'
Autor:
Kristine L. Haftorn, Julia Romanowska, Yunsung Lee, Christian M. Page, Per M. Magnus, Siri E. Håberg, Jon Bohlin, Astanand Jugessur, William R. P. Denault
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Background DNA methylation (DNAm) is robustly associated with chronological age in children and adults, and gestational age (GA) in newborns. This property has enabled the development of several epigenetic clocks that can accurately predict
Externí odkaz:
https://doaj.org/article/9440ffacbf8147afa22264161d9bbb13
Autor:
Julia Romanowska, Haakon E. Nustad, Christian M. Page, William R. P. Denault, Yunsung Lee, Maria C. Magnus, Kristine L. Haftorn, Miriam Gjerdevik, Boris Novakovic, Richard Saffery, Håkon K. Gjessing, Robert Lyle, Per Magnus, Siri E. Håberg, Astanand Jugessur
Publikováno v:
Human Genomics, Vol 17, Iss 1, Pp 1-22 (2023)
Abstract Background Assisted reproductive technologies (ART) may perturb DNA methylation (DNAm) in early embryonic development. Although a handful of epigenome-wide association studies of ART have been published, none have investigated CpGs on the X
Externí odkaz:
https://doaj.org/article/9bf951f413f441ab83a328c0a5e0d80b
Autor:
Kristine L. Haftorn, William R. P. Denault, Yunsung Lee, Christian M. Page, Julia Romanowska, Robert Lyle, Øyvind E. Næss, Dana Kristjansson, Per M. Magnus, Siri E. Håberg, Jon Bohlin, Astanand Jugessur
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
CpG sites associated with gestational age are predominantly found in nucleated red blood cells, which point to an epigenetic signature of erythropoiesis as being partly responsible for this association.
Externí odkaz:
https://doaj.org/article/685ca7f611554c978bb43c19b97d8d3b
Autor:
Siri E. Håberg, Christian M. Page, Yunsung Lee, Haakon E. Nustad, Maria C. Magnus, Kristine L. Haftorn, Ellen Ø. Carlsen, William R. P. Denault, Jon Bohlin, Astanand Jugessur, Per Magnus, Håkon K. Gjessing, Robert Lyle
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Timing of assisted reproduction technology (ART) procedures coincides with extensive epigenetic remodeling early after conception. Here the authors identify 176 DNA methylation differences in cord blood of newborns conceived with ART. including genes
Externí odkaz:
https://doaj.org/article/c81f2b99b3244df6aaec3ae62d0b4fa2
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-20 (2021)
Abstract Background Traditional methods for single-variant genome-wide association study (GWAS) incur a substantial multiple-testing burden because of the need to test for associations with a vast number of single-nucleotide polymorphisms (SNPs) simu
Externí odkaz:
https://doaj.org/article/5578c9ee8fdd430b9331999588fdabfc
Autor:
William R. P. Denault, Julia Romanowska, Øyvind Helgeland, Bo Jacobsson, Håkon K. Gjessing, Astanand Jugessur
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-9 (2021)
Abstract Background Birth weight (BW) is one of the most widely studied anthropometric traits in humans because of its role in various adult-onset diseases. The number of loci associated with BW has increased dramatically since the advent of whole-ge
Externí odkaz:
https://doaj.org/article/9e4f6aa216734cf183196c5a8e77f0f7
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-15 (2021)
Abstract Background We present here a computational shortcut to improve a powerful wavelet-based method by Shim and Stephens (Ann Appl Stat 9(2):665–686, 2015. https://doi.org/10.1214/14-AOAS776 ) called WaveQTL that was originally designed to iden
Externí odkaz:
https://doaj.org/article/b21da84162cf445f868bb68929b8a7a0
Autor:
Yunsung Lee, Kristine L. Haftorn, William R. P. Denault, Haakon E. Nustad, Christian M. Page, Robert Lyle, Sindre Lee-Ødegård, Gunn-Helen Moen, Rashmi B. Prasad, Leif C. Groop, Line Sletner, Christine Sommer, Maria C. Magnus, Håkon K. Gjessing, Jennifer R. Harris, Per Magnus, Siri E. Håberg, Astanand Jugessur, Jon Bohlin
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-13 (2020)
Abstract Background Epigenetic clocks have been recognized for their precise prediction of chronological age, age-related diseases, and all-cause mortality. Existing epigenetic clocks are based on CpGs from the Illumina HumanMethylation450 BeadChip (
Externí odkaz:
https://doaj.org/article/0615d625d2304aafb5a4fea374fd2938
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-2 (2021)
A Correction to this paper has been published: https://doi.org/10.1186/s12859-021-03979-y
Externí odkaz:
https://doaj.org/article/7cb6e8b7c33b4f0d9ecaac1d0db37c33
Publikováno v:
PLoS Computational Biology
e1010268
e1010268
Bias from weak instruments may undermine the ability to estimate causal effects in instrumental variable regression (IVR). We present here a new approach to handling weak instrument bias through the application of a new type of instrumental variable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a6c42e4065923644e964457644cb163
https://hdl.handle.net/11250/3024870
https://hdl.handle.net/11250/3024870
