Výsledky vyhledávání - "William R. Mathews"

Proteomics in the pharmaceutical and biotechnology industry: a look to the next decade

Autor: Jennie R. Lill, Christopher M. Rose, William R. Mathews, Markus Schirle

Publikováno v: Expert review of proteomics. 18(7)

Pioneering technologies such as proteomics have helped fuel the biotechnology and pharmaceutical industry with the discovery of novel targets and an intricate understanding of the activity of therapeutics and their various activities in vitro and in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4efc8387ae81c14cfb78620d20437469
https://pubmed.ncbi.nlm.nih.gov/34320887

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Anti-CD22 and anti-CD79b antibody-drug conjugates preferentially target proliferating B cells

Autor: Shan Chung, Dimitry M. Danilenko, Dongwei Li, Andrew Polson, Jacqueline McBride, Bing Zheng, Randall C. Dere, Marna Williams, Chae Janeka Reed, William R. Mathews, Saileta Prabhu, Caroline Looney, Kirsten Achilles Poon, Franklin Fuh

Publikováno v: British Journal of Pharmacology. 174:628-640

SummaryBackground and purpose CD22 and CD79b are cell-surface receptors expressed on B-cell-derived malignancies such as non-Hodgkin's lymphoma (NHL). An anti-mitotic agent monomethyl auristatin E was conjugated to anti-CD22 and anti-CD79b antibodies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ba8ef110895529ddb8820aff512f66f5
https://doi.org/10.1111/bph.13697

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Sa2025 Etrolizumab-Mediated Ex Vivo Modulation of Beta7 Cell Surface Receptors in Nonhuman Primate and Human Peripheral Blood Supports the Proposed Mechanism of Action

Autor: Caroline Looney, Sha Klabunde, Clarissa F. Johnson, Franklin Fuh, William R. Mathews, Dimitry M. Danilenko, Kathleen Howell, Marna Williams, Sharon O'Byrne

Publikováno v: Gastroenterology. 142:S-383

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::51762c89031d43b866a8710b76d7d848
https://doi.org/10.1016/s0016-5085(12)61451-6

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Secondary Breast Cancer of Prostatic Origin

Autor: Durwood L. Kirk, William R. Mathews, James H. Campbell, Sam D. Cummins

Publikováno v: JAMA. 179:458

CARCINOMA of the prostate is noted for its widespread metastases and has been reported to invade practically every organ and tissue of the body. However, it is unusual for carcinoma of the prostate, or any other type of cancer, to metastasize to the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c0dc23be2febe98318eadcd759b280a
https://doi.org/10.1001/jama.1962.03050060068016a

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