Zobrazeno 1 - 10
of 24
pro vyhledávání: '"William R. Fairweather"'
Autor:
Mario Cazzola, William R. Fairweather, William W. Howard, Marc F. Goldstein, Frank Lloyd Dini, Luigino Calzetta, Nicola A. Hanania
Publikováno v:
Pulmonary Pharmacology & Therapeutics. 53:20-26
This pooled analysis of double-blind, randomized, placebo-controlled trials aimed to investigate the impact of DOxofylline compaRed tO THEOphylline (DOROTHEO 1 and DOROTHEO 2 studies) on functional and clinical outcomes in asthma. Asthmatic patients
Autor:
Marc F. Goldstein, William W. Howard, Mario Cazzola, Paola Rogliani, Luigino Calzetta, William R. Fairweather, Maria Gabriella Matera
Doxofylline, an oral methylxanthine with bronchodilator and anti-inflammatory activities, offers a promising alternative to theophylline due to its superior efficacy/safety profile. No long-term studies on the efficacy and safety of doxofylline are c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8d4797a8fb8d67833b1ba4eb911095a
http://hdl.handle.net/11591/424032
http://hdl.handle.net/11591/424032
Autor:
William R. Fairweather
Publikováno v:
Journal of Biopharmaceutical Statistics. 15:253-264
Discrepancies in the data of a bioequivalence study led to questions about the procedures used in the analytical laboratory. In this article we describe some statistical and graphical procedures that were used to explore the causes of a process failu
Autor:
William R. Fairweather
Publikováno v:
Journal of Biopharmaceutical Statistics. 13:415-423
When marketed lots of pharmaceutical products produce a number of out-of-specification (OOS) samples, it can be very disruptive. In some cases such lots must be recalled, at substantial expense. We present a model of the probability of OOS samples an
Autor:
Stephen L. George, Genell L. Knatterud, Franca B. Barton, C.E. Davis, Frank W. Rockhold, Tom Honohan, Richard Mowery, Robert O'Neill, William R. Fairweather
Publikováno v:
Controlled Clinical Trials. 19:477-493
In the wake of reports of falsified data in one of the trials of the National Surgical Adjuvant Project for Breast and Bowel Cancer supported by the National Cancer Institute, clinical trials came under close scrutiny by the public, the press, and Co
Autor:
William R. Fairweather
Publikováno v:
Drug Information Journal. 30:875-879
The emphasis in this essay will be on statistical issues in the assessment of safety, and in particular, in putting these issues in context. The present status and future goals for the assessment o...
Autor:
Kamal K. Midha, Rabi Patnaik, William H. Barr, Lawrence J. Lesko, Leslie Z. Benet, John Hooper, Andre J. Jackson, Vinod P. Shah, Patrick K. Noonan, William R. Gillespie, William R. Fairweather, Roger L. Williams, Mario A. Gonzalez, Michael R. Dobrinska, Lazslo Endrenyi, Douwe D. Breimer, Avraham Yacobi
Publikováno v:
Pharmaceutical Research. 13:1590-1594
Publikováno v:
Journal of Pharmaceutical Sciences. 84:1322-1326
Drug stability studies are expensive and time consuming. Multiple batches are studied to ensure that a product will consistently remain within specifications for its entire expiration dating period. Some of these studies involve the same drug product
Autor:
William R. Fairweather
Publikováno v:
Journal of biopharmaceutical statistics. 22(1)