Zobrazeno 1 - 10
of 15
pro vyhledávání: '"William R. Cooke"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 1947 (2024)
Throughout pregnancy, some degree of insulin resistance is necessary to divert glucose towards the developing foetus. In gestational diabetes mellitus (GDM), insulin resistance is exacerbated in combination with insulin deficiency, causing new-onset
Externí odkaz:
https://doaj.org/article/3e57ef911d8e4db48821ca970b971d4c
Publikováno v:
Maternal-Fetal Medicine, Vol 3, Iss 2, Pp 151-160 (2021)
Abstract. The syncytiotrophoblast, a fused single-cell layer between mother and fetus, constitutively releases extracellular vesicles (STBEV) directly into the maternal circulation. STBEV contain a variety of proteins and RNA which can be targeted to
Externí odkaz:
https://doaj.org/article/fe713279bcba4cdeb89169a21c1236ce
Autor:
Abi G. Yates, Ryan C. Pink, Uta Erdbrügger, Pia R‐M. Siljander, Elizabeth R. Dellar, Paschalia Pantazi, Naveed Akbar, William R. Cooke, Manu Vatish, Emmanuel Dias‐Neto, Daniel C. Anthony, Yvonne Couch
Publikováno v:
Journal of Extracellular Vesicles, Vol 11, Iss 1, Pp n/a-n/a (2022)
Abstract Previously thought to be nothing more than cellular debris, extracellular vesicles (EVs) are now known to mediate physiological and pathological functions throughout the body. We now understand more about their capacity to transfer nucleic a
Externí odkaz:
https://doaj.org/article/40462d95fe7b4552b8cc2cd06f1c1527
Autor:
William R. Cooke, Ulla K. Hemmilä, Alison L. Craik, Chimwemwe J. Mandula, Priscilla Mvula, Ausbert Msusa, Gavin Dreyer, Rhys Evans
Publikováno v:
BMC Nephrology, Vol 19, Iss 1, Pp 1-8 (2018)
Abstract Background Obstetric-related acute kidney injury (AKI) is thought to be a key contributor to the overall burden of AKI in low resource settings, causing significant and preventable morbidity and mortality. However, epidemiological data to co
Externí odkaz:
https://doaj.org/article/b1ef26c90b5e43edadb7319c2e8f5027
Autor:
Thomas E. Bartlett, Kantaraja Chindera, Jacqueline McDermott, Charles E. Breeze, William R. Cooke, Allison Jones, Daniel Reisel, Smita T. Karegodar, Rupali Arora, Stephan Beck, Usha Menon, Louis Dubeau, Martin Widschwendter
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Women with germline variants in BRCA genes are predisposed to ovarian cancer. In this study, the authors demonstrate that fimbrial tissue from the ovary, the site of ovarian cancer, in BRCAmutant carriers contains marked DNA methylation changes compa
Externí odkaz:
https://doaj.org/article/c0f2825e826f439a82d6b3c7a397ac25
Publikováno v:
Maternal-Fetal Medicine. 4:130-140
Autor:
Abi G, Yates, Ryan C, Pink, Uta, Erdbrügger, Pia R-M, Siljander, Elizabeth R, Dellar, Paschalia, Pantazi, Naveed, Akbar, William R, Cooke, Manu, Vatish, Emmanuel, Dias-Neto, Daniel C, Anthony, Yvonne, Couch
Publikováno v:
Journal of Extracellular Vesicles
It is clear from Part I of this series that extracellular vesicles (EVs) play a critical role in maintaining the homeostasis of most, if not all, normal physiological systems. However, the majority of our knowledge about EV signalling has come from s
Autor:
Alison Craik, Rhys Evans, Ausbert Thoko Msusa, Ulla Hemmila, Gavin Dreyer, Viviane Calice-Silva, Jochen G. Raimann, Nathan W. Levin, Chimwemwe J. Mandula, Roberto Pecoits-Filho, William R. Cooke, Priscilla Mvula
Publikováno v:
Kidney International Reports, Vol 3, Iss 1, Pp 178-184 (2018)
Kidney International Reports
Kidney International Reports
Introduction Obstetric-related acute kidney injury (AKI) is associated with adverse outcomes for mother and fetus, particularly in low-income countries. However, laboratory-independent tools to facilitate diagnosis are lacking. We assessed the diagno
Autor:
Kim Soulsby, Kelly Place, Jane Siddall, Anne Billett, Suzie Gleeson, Andrew Walden, William R. Cooke, Andrew Jacques
Publikováno v:
European Journal of Obstetrics, Gynecology, and Reproductive Biology
European Journal of Obstetrics & Gynecology and Reproductive Biology
European Journal of Obstetrics & Gynecology and Reproductive Biology
Autor:
Ulla Hemmila, Chimwemwe J. Mandula, Rhys Evans, Ausbert Thoko Msusa, William R. Cooke, Gavin Dreyer, Priscilla Mvula, Alison Craik
Publikováno v:
BMC Nephrology
BMC Nephrology, Vol 19, Iss 1, Pp 1-8 (2018)
BMC Nephrology, Vol 19, Iss 1, Pp 1-8 (2018)
Background Obstetric-related acute kidney injury (AKI) is thought to be a key contributor to the overall burden of AKI in low resource settings, causing significant and preventable morbidity and mortality. However, epidemiological data to corroborate