Zobrazeno 1 - 10
of 111
pro vyhledávání: '"William R. Atchley"'
Publikováno v:
Evolutionary Bioinformatics, Vol 2, Pp 251-259 (2006)
We present computational methods and subroutines to compute Gaussian quadrature integration formulas for arbitrary positive measures. For expensive integrands that can be factored into well-known forms, Gaussian quadrature schemes allow for efficient
Externí odkaz:
https://doaj.org/article/e833322b005c426bb0e244aea05b8bd5
Autor:
Zhi Wang, William R. Atchley
Publikováno v:
Evolutionary Bioinformatics, Vol 2 (2006)
The basic helix-loop-helix (bHLH) family of transcription factors is used as a paradigm to explore structural implications of periodicity patterns in amino acid sequence variability. A Boltzmann-Shannon entropy profile represents site-by-site amino a
Externí odkaz:
https://doaj.org/article/a0d1f4d9c756477e9d715fbbac9c697c
Publikováno v:
Evolutionary Bioinformatics, Vol 2 (2006)
We present computational methods and subroutines to compute Gaussian quadrature integration formulas for arbitrary positive measures. For expensive integrands that can be factored into well-known forms, Gaussian quadrature schemes allow for efficient
Externí odkaz:
https://doaj.org/article/c46d607de1ae4244a3eb96617b10eb31
Publikováno v:
Plant disease. 86(10)
Flue-cured tobacco (Nicotiana tabacum) cultivar Coker 371-Gold (C 371-G) possesses a dominant gene, Ph, that confers high resistance to black shank disease, caused by race 0 of the soil-borne pathogen Phytophthora parasitica var. nicotianae. The orig
Autor:
Lisa G. McFerrin, William R. Atchley
Publikováno v:
Genome Biology and Evolution
Transcription factors (TFs) are essential for the regulation of gene expression and often form emergent complexes to perform vital roles in cellular processes. In this paper, we focus on the parallel Max and Mlx networks of TFs because of their criti
Publikováno v:
Bioinformatics. 24:2177-2183
Motivation: In a nucleotide or amino acid sequence, not all sites evolve at the same rate, due to differing selective constraints at each site. Currently in computational molecular evolution, models incorporating rate heterogeneity always share two a
Autor:
Jieping Zhao, William R. Atchley
Publikováno v:
Molecular Biology and Evolution. 24:192-202
Multivariate statistical analyses are used to explore the molecular architecture of the DNA-binding and dimerization regions of basic helix-loop-helix (bHLH) proteins. Alphabetic amino acid data are transformed to biologically meaningful quantitative
Autor:
William R. Atchley, Michael J. Buck
Publikováno v:
Journal of Molecular Evolution. 56:742-750
The basic helix-loop-helix (bHLH) family of proteins is a group of functionally diverse transcription factors found in both plants and animals. These proteins evolved early in eukaryotic cells before the split of animals and plants, but appear to fun
Publikováno v:
Molecular Biology and Evolution. 18:1502-1511
Phylogenetic analyses of 110 serpin protein sequences revealed clades consistent with independent phylogenetic analyses based on exon-intron structure and diagnostic amino acid sites. Trees were estimated by maximum likelihood, neighbor joining, and
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. 55:B455-B461
Small body size is associated with superior longevity in several intraspecies comparisons, including dogs bred for specific forms of work, mice and rats fed diets low in calories, rats fed diets low in methionine, and mutant mice whose levels of grow