Zobrazeno 1 - 10
of 63
pro vyhledávání: '"William R, Ford"'
Publikováno v:
Healthcare, Vol 11, Iss 8, p 1125 (2023)
A high percentage of asthma patients have symptoms that are not well controlled, despite effective drugs being available. One potential reason for this may be that poor inhaler technique limits the dose delivered to the lungs, thereby reducing the th
Externí odkaz:
https://doaj.org/article/632ba03acae14fdd879b2a59aa4a9a4a
Publikováno v:
Pharmacy, Vol 10, Iss 3, p 59 (2022)
The role of the community pharmacist has evolved to include the provision of more clinical services for patients. Those people who have stable chronic conditions will be managed in community pharmacies. This qualitative study used semi-structured in-
Externí odkaz:
https://doaj.org/article/fafd34e4b8eb42d1afba8d480b408a6e
Autor:
Patricia Ramos Ramirez, Henric Olsson, Brendan J. Canning, Mariska P. M. van den Berg, Eva Stoffels, William R. Ford, Gunnar Nilsson, Mark A. Birrell, Sven-Erik Dahlén, Mikael Adner, Lennart K. A. Lundblad, Herman Meurs, Maria G. Belvisi
Research using animal models of asthma is currently dominated by mouse models. This has been driven by the comprehensive knowledge on inflammatory and immune reactions in mice, as well as tools to produce genetically modified mice. Many of the identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4895027077137cf1c32fbf5036ba43ce
Autor:
Qiong Huang, Jpt Ward, Emma Jane Kidd, Catherine M. Hawrylowicz, Wei Wang, Xiaonan Du, Richard T. Bruce, Christopher Corrigan, Yong-chang Sun, Keir Lewis, William R. Ford, T-R Ho, Daniela Riccardi, David R Thickett, Sebastian T Lugg, Luis A. J. Mur, Bethan Mansfield, Paul J. Kemp, Ping Huang
Publikováno v:
BTS/ BALR/ BLF Early Career Investigator Awards Symposium.
Introduction Exposure to urban particulate matter (UPM) exacerbates the development of asthma and COPD. UPM exposure triggers the release of ‘alarmins’ by the airway epithelium, which causes an inflammatory response such as acceleration of the ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9f5dd04385bc4e3e31dcaa2f7f07425
https://doi.org/10.1136/thorax-2019-btsabstracts2019.4
https://doi.org/10.1136/thorax-2019-btsabstracts2019.4
Autor:
William R. Ford, Andrea Brancale, Jeremy P.T. Ward, Daniela Riccardi, Salvatore Ferla, Paul J. Kemp, Christopher Corrigan, Kenneth J. Broadley, Polina Yarova, Emma Jane Kidd, Ping Huang, Martin Schepelmann, Vsevolod Telezhkin
Publikováno v:
Airway pharmacology and treatment.
Background: Inhibitors of the extracellular calcium-sensing receptor (CaSR), termed calcilytics, were developed to evoke pulsatile changes in plasma parathyroid hormone (PTH) levels as a novel anti-osteoporotic treatment. Recently we have shown that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::349dbea296d9f5c6cf3f331e3b4f7b99
https://doi.org/10.1183/13993003.congress-2018.pa1060
https://doi.org/10.1183/13993003.congress-2018.pa1060
Autor:
Ping Huang, Christopher Corrigan, Emma Jane Kidd, Jeremy P. T. Ward, Paul J. Kemp, William R. Ford, Kenneth J. Broadley, Martin Schepelmann, Polina Yarova, Daniela Riccardi
Publikováno v:
Clinical Problems.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee4caa7aa68e7610d1be5d37b17f4ced
https://doi.org/10.1183/13993003.congress-2018.pa5483
https://doi.org/10.1183/13993003.congress-2018.pa5483
Autor:
William R. Ford, Emma Jane Kidd, Elinor John, Rhys L. Evans, Joachim Jakob Bugert, Alan Edward Blair, Kenneth J. Broadley
Publikováno v:
Clinical Science. 125:471-482
Viral exacerbations of allergen-induced pulmonary inflammation in pre-clinical models reportedly reduce the efficacy of glucocorticoids to limit pulmonary inflammation and airways hyper-responsiveness to inhaled spasmogens. However, exacerbations of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6589012ab1d677a52f253141b1817545
https://doi.org/10.1042/cs20130130
https://doi.org/10.1042/cs20130130
Publikováno v:
Vascular Pharmacology
Tryptamine is an endogenous and dietary indoleamine-based trace amine implicated in cardiovascular pathologies, including hypertension, migraine and myocardial infarction. This study aimed at identifying the signalling pathways for the vasoconstricto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34678219d43dc9c1ee051958cb0080f1
https://doi.org/10.1016/j.vph.2012.10.007
https://doi.org/10.1016/j.vph.2012.10.007
Autor:
Richard G. Knowles, William R. Ford, Kenneth J. Broadley, Emma Jane Kidd, Anthony T. Nials, Rhys L. Evans
Publikováno v:
Pulmonary Pharmacology & Therapeutics. 25:453-464
Pre-clinical evaluation of asthma therapies requires animal models of chronic airways inflammation, airway hyperresponsiveness (AHR) and lung remodelling that accurately predict drug effectiveness in human asthma. However, most animal models focus on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c25826e959cef9c0a9c8e4f1893cbdd2
https://doi.org/10.1016/j.pupt.2012.08.004
https://doi.org/10.1016/j.pupt.2012.08.004
Publikováno v:
European journal of pharmacology. 801
Magnesium sulphate is a potential treatment for acute severe asthma. However, the mechanisms and dose-response relationships are poorly understood. The first objective of this study was to examine whether inhaled magnesium sulphate exerts bronchodila
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ab652e43d889f93695043597bcc2b03
https://pubmed.ncbi.nlm.nih.gov/28284753
https://pubmed.ncbi.nlm.nih.gov/28284753