Zobrazeno 1 - 10
of 12
pro vyhledávání: '"William Pinney"'
Autor:
Joseph R. Palmeri, Brianna M. Lax, Joshua M. Peters, Lauren Duhamel, Jordan A. Stinson, Luciano Santollani, Emi A. Lutz, William Pinney, Bryan D. Bryson, K. Dane Wittrup
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Although co-stimulation of T cells with agonist antibodies targeting 4-1BB (CD137) improves antitumor immune responses in preclinical studies, clinical success has been limited by on-target, off-tumor activity. Here, we report the developmen
Externí odkaz:
https://doaj.org/article/8e65e3d9cba14ba3930a59f163a199fe
Autor:
Emi A Lutz, K Dane Wittrup, Joseph R Palmeri, Brianna M Lax, Josh M Peters, Lauren Duhamel, Jordan A Stinson, Luciano Santollani, William Pinney, Bryan D Bryson
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/1d4f4929a5304e66974b9d6a359dc8a4
Autor:
Novalia Pishesha, Thibault Harmand, Claire Carpenet, Xin Liu, Atul Bhan, Ashraful Islam, Renate van den Doel, William Pinney, Hidde L. Ploegh
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(43)
The distribution of Ly6C/G-positive cells in response to an infection of the mouse respiratory tract with influenza A virus was followed noninvasively over time by immuno-positron emission tomography. We converted nanobodies that recognize Ly6C and L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7082cd0a784e13b187177f791da60e8b
https://pubmed.ncbi.nlm.nih.gov/36252038
https://pubmed.ncbi.nlm.nih.gov/36252038
Autor:
Joseph R. Palmeri, Brianna M. Lax, Joshua M. Peters, Lauren Duhamel, Jordan A. Stinson, Luciano Santollani, Emi A. Lutz, William Pinney, Bryan D. Bryson, K. Dane Wittrup
Although co-stimulation of T cells with agonist antibodies targeting 4-1BB (CD137) improves antitumor immune responses in preclinical studies, clinical development has been hampered by on-target, off-tumor toxicity. Here, we report the development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c9a26a29bffbde5f9ff8ba4bf52371d
https://doi.org/10.1101/2023.01.30.526116
https://doi.org/10.1101/2023.01.30.526116
Autor:
Hidde L. Ploegh, Yushu J. Xie, Novalia Pishesha, William Pinney, Weiyi Ma, Fabian B. H. Rehm, Thibault J. Harmand
Publikováno v:
ACS Chemical Biology. 16:1201-1207
Red blood cells (RBCs) can serve as vascular carriers for drugs, proteins, peptides, and nanoparticles. Human RBCs remain in the circulation for ∼120 days, are biocompatible, and are immunologically largely inert. RBCs are cleared by the reticuloen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e9070a6a0635908ca40a56a86e036b7
https://doi.org/10.1021/acschembio.1c00216
https://doi.org/10.1021/acschembio.1c00216
Autor:
Novalia Pishesha, Nicholas McCaul, Martín A. Rossotti, Weiyi Ma, Robine Janssen, Gualberto González-Sapienza, Liyan Y. Smeding, Tao Fang, William Pinney, Ashraful Islam, Yushu J. Xie, Harun R. Sugito, Thibault J. Harmand, Hidde L. Ploegh, Leif S. Ludwig
Publikováno v:
Nature Biomedical Engineering. 5:1389-1401
The association of autoimmune diseases with particular allellic products of the class-II major histocompatibility complex (MHCII) region implicates the presentation of the offending self-antigens to T cells. Because antigen-presenting cells are toler
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ee1ee81ba3281036f5c9c51fe6fc495
https://doi.org/10.1038/s41551-021-00738-5
https://doi.org/10.1038/s41551-021-00738-5
Autor:
Mariel J. Liebeskind, Novalia Pishesha, Marjorie Cornejo Pontelli, Ma. Xenia G. Ilagan, William Buchser, Hailey Heston, Renate Van den Doel, Charlotte Wijne, Patrique Praest, Sean P. J. Whelan, Maria A. Vakaki, Thibault J. Harmand, Hidde L. Ploegh, Nicholas McCaul, Emmanuel J. H. J. Wiertz, William Pinney, Paul W. Rothlauf, Louis Marie Bloyet, Elisha R. Verhaar, Robert Jan Lebbink, Ryan K. Alexander
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Vaccines remain the best hope of curtailing SARS-CoV-2 transmission, morbidity, and mortality. Currently available vaccines require cold storage and sophisticated manufacturing capacity, complicating their distribution, especially in les
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8213e9b348efbd93dd7df6d9048f0e45
https://pubmed.ncbi.nlm.nih.gov/34654739
https://pubmed.ncbi.nlm.nih.gov/34654739
Autor:
Harun R. Sugito, Novalia Pishesha, Yushu Xie, Nicholas McCaul, Liyan Y. Smeding, Tao Fang, Ashraful Islam, Robine Janssen, Thibault J. Harmand, William Pinney, Hidde L. Ploegh, Leif S. Ludwig, Weiyi Ma
The association of autoimmune diseases with particular allelic variants of Class II MHC (MHCII) products implicates presentation of the offending self-antigen(s) to T cells. Antigen presenting cells are tolerogenic when they encounter antigen under n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f377515d5135a6c1aa58d2c522a811b2
https://doi.org/10.21203/rs.3.rs-192181/v1
https://doi.org/10.21203/rs.3.rs-192181/v1