Zobrazeno 1 - 10
of 42
pro vyhledávání: '"William P. Watkinson"'
Autor:
Carol A Edwards, William MD Watkinson, Stephanie B Telerman, Lisa C Hulsmann, Russell S Hamilton, Anne C Ferguson-Smith
Publikováno v:
eLife, Vol 12 (2023)
In mouse and human, genes subjected to genomic imprinting have been shown to function in development, behavior, and post-natal adaptations. Failure to correctly imprint genes in human is associated with developmental syndromes, adaptive, and metaboli
Externí odkaz:
https://doaj.org/article/13033a2ac6d44daebe192428a6bf7da2
Autor:
Renaud Vincent, Premkumari Kumarathasan, Patrick Goegan, Stephen G. Bjarnason, Josée Guénette, Subramanian Karthikeyan, Errol M. Thomson, Ian Y. Adamson, William P. Watkinson, Bruno Battistini, Frederick J. Miller
Publikováno v:
Chemosphere. 296
Short-term increases in particulate matter (PM) are associated with heightened morbidity and mortality from cardiovascular causes. Inhalation of PM is known to increase endothelin (ET)-1 levels. Yet, less is known about particle composition-related c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::690d7535fa1e3efce9004415de500aa3
https://pubmed.ncbi.nlm.nih.gov/35157883
https://pubmed.ncbi.nlm.nih.gov/35157883
Autor:
William H. Rowan, Wayne E. Cascio, Aimen K. Farraj, William P. Watkinson, Mehdi S. Hazari, Daniel L. Costa, Alex P. Carll, Najwa Haykal-Coates, Darrell W. Winsett, Allen D. Ledbetter, Abraham Nyska
Publikováno v:
Inhalation Toxicology. 22:355-368
Ambient particulate matter (PM) exposure is linked to cardiovascular events and death, especially among individuals with heart disease. A model of toxic cardiomyopathy was developed in Spontaneously Hypertensive Heart Failure (SHHF) rats to explore p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ab1cc9e29a4f4cbe3f6ed9e04d20023
https://doi.org/10.3109/08958370903365692
https://doi.org/10.3109/08958370903365692
Autor:
Urmila P. Kodavanti, Mette C. Schladweiler, Lindsay B. Wichers, Allen D. Ledbetter, Daniel L. Costa, Julianne P. Nolan, Darrell W. Winsett, William P. Watkinson
Publikováno v:
Inhalation Toxicology. 16:391-405
Epidemiological studies have reported statistically significant associations between the levels of ambient particulate matter (PM) and the incidence of morbidity and mortality, particularly among persons with cardiopulmonary disease. While similar ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61a64797eef74a9611f050aacba55f32
https://doi.org/10.1080/08958370490439696
https://doi.org/10.1080/08958370490439696
Autor:
Julianne P. Nolan, Daniel L. Costa, Mette C. Schladweiler, Urmila P. Kodavanti, William P. Watkinson, Matthew J. Campen
Publikováno v:
Journal of Toxicology and Environmental Health, Part A. 65:1615-1631
Particulate matter air pollution has been associated with cardiopulmonary morbidity and mortality in many recent epidemiological studies. Previous toxicological research has demonstrated profound cardiac and thermoregulatory changes in rats following
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a63564f64112ee24a11e9b481ef08d42
https://doi.org/10.1080/00984100290071694
https://doi.org/10.1080/00984100290071694
Autor:
Mette C. Schladweiler, Julianne P. Nolan, Urmila P. Kodavanti, Daniel L. Costa, William P. Watkinson, Matthew J. Campen, Paul A. Evansky
Publikováno v:
Toxicological Sciences. 64:243-252
Recent epidemiological studies have shown an association between daily morbidity and mortality and ambient particulate matter (PM) air pollution. It has been proposed that bioavailable metal constituents of PM are responsible for many of the reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68d27710dde815333a42a99e9ad6aa7d
https://doi.org/10.1093/toxsci/64.2.243
https://doi.org/10.1093/toxsci/64.2.243
Autor:
William P. Watkinson, Daniel L. Costa, Julianne P. Nolan, Matthew J. Campen, Lindsay B. Wichers, Urmila P. Kodavanti
Publikováno v:
Journal of Thermal Biology. 26:331-338
(1) In response to exposure to toxic xenobiotic agents, rodents demonstrate significant acute and subacute decreases in important indices of thermoregulatory and cardiovascular function. (2) This response has been observed in a number of studies in o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fbad139cbd8718fc3fb2e3be52cfda3
https://doi.org/10.1016/s0306-4565(01)00040-7
https://doi.org/10.1016/s0306-4565(01)00040-7
Autor:
Matthew J. Campen, Mette C. Schladweiler, Kay M. Crissman, Allen D. Ledbetter, Gary E. Hatch, Darrell W. Winsett, Judy R. Richards, William P. Watkinson, Urmila P. Kodavanti, Daniel L. Costa
Publikováno v:
Toxicology and Applied Pharmacology. 164:250-263
Cardiovascular disease is considered a probable risk factor of particulate matter (PM)-related mortality and morbidity. It was hypothesized that rats with hereditary systemic hypertension and underlying cardiac disease would be more susceptible than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aa0b0128ed0c6f7963fd7dd682c0825
https://doi.org/10.1006/taap.2000.8899
https://doi.org/10.1006/taap.2000.8899
Autor:
Jerry W. Highfill, Urmila P. Kodavanti, William P. Watkinson, Daniel L. Costa, W-Y Su, Kevin L. Dreher, Matthew J. Campen
Publikováno v:
Journal of Thermal Biology. 25:131-137
Epidemiological studies have correlated human exposure to ambient particulate matter (PM) with increased morbidity and mortality, particularly in cardiopulmonary-compromised individuals. We conducted experimental studies using radiotelemetry methodol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67b9dde99ac66c2ff76a2f5dd07e231c
https://doi.org/10.1016/s0306-4565(99)00090-x
https://doi.org/10.1016/s0306-4565(99)00090-x
Autor:
Matthew J. Campen, William P. Watkinson, Rudolph Mebane, Gary E. Hatch, John L. McKee, Joel Norwood
Publikováno v:
Journal of Thermal Biology. 25:81-89
1. Ozone (O 3 ) inhalation induces a hypothermic response in rodents characterized primarily by core body temperature ( T CO ) and heart rate (HR) decreases. 2. This preliminary study examined T CO , HR, and electrocardiographic changes in rats and g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::519ada31b000580e13dd61721f733f8f
https://doi.org/10.1016/s0306-4565(99)00041-8
https://doi.org/10.1016/s0306-4565(99)00041-8