Zobrazeno 1 - 10
of 24
pro vyhledávání: '"William P. Russ"'
Autor:
Yusuf Talha Tamer, William P. Russ, Fatma S. Coskun, Michael Farid, Marinelle Rodrigues, Andrew Y. Koh, Erdal Toprak, Ilona K. Gaszek
Publikováno v:
Molecular Biology and Evolution
Bacteriophages and bacterial toxins are promising antibacterial agents to treat infections caused by multidrug-resistant (MDR) bacteria. In fact, bacteriophages have recently been successfully used to treat life-threatening infections caused by MDR b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b378e8bd506d74a318d8ee65eb59b320
https://doi.org/10.1093/molbev/msab190
https://doi.org/10.1093/molbev/msab190
Autor:
Neel H Shah, Qi Wang, Qingrong Yan, Deepti Karandur, Theresa A Kadlecek, Ian R Fallahee, William P Russ, Rama Ranganathan, Arthur Weiss, John Kuriyan
Publikováno v:
eLife, Vol 5 (2016)
The sequence of events that initiates T cell signaling is dictated by the specificities and order of activation of the tyrosine kinases that signal downstream of the T cell receptor. Using a platform that combines exhaustive point-mutagenesis of pept
Externí odkaz:
https://doaj.org/article/b39beca68cc0453aa3b66feed4aec35e
Autor:
Robert G Smock, Olivier Rivoire, William P Russ, Joanna F Swain, Stanislas Leibler, Rama Ranganathan, Lila M Gierasch
Publikováno v:
Molecular Systems Biology, Vol 6, Iss 1, Pp 1-10 (2010)
Abstract Allosteric coupling between protein domains is fundamental to many cellular processes. For example, Hsp70 molecular chaperones use ATP binding by their actin‐like N‐terminal ATPase domain to control substrate interactions in their C‐te
Externí odkaz:
https://doaj.org/article/b2ba0e6b5cfe4e2a91bd8ce9f67a48bb
Protein structure, function, and evolution depend on local and collective epistatic interactions between amino acids. A powerful approach to defining these interactions is to construct models of couplings between amino acids that reproduce the empiri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0fecaf8d08eac397dccc18ecfc7de57
https://doi.org/10.1101/2021.04.22.441025
https://doi.org/10.1101/2021.04.22.441025
Autor:
Yusuf Talha Tamer, Erdal Toprak, Fatma S. Coskun, Andrew Y. Koh, William P. Russ, Ilona K. Gaszek, Marinelle Rodrigues, Michael Farid
Bacteriophages and bacterial toxins are promising antibacterial agents to treat infections caused by multidrug resistant (MDR) bacteria. In fact, bacteriophages have recently been successfully used to treat life-threatening infections caused by MDR b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69d401e700775a946fe22f41ffc7575b
https://doi.org/10.1101/2020.10.28.332486
https://doi.org/10.1101/2020.10.28.332486
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The ribosome is a large, complex, and essential biomolecular machine. Despite its importance in all domains of life, the long-range interactions that regulate ribosome function are poorly understood. Here we report that statistical coupl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff6f1f2af0581706e852b0a29dd7834c
https://pubmed.ncbi.nlm.nih.gov/32747536
https://pubmed.ncbi.nlm.nih.gov/32747536
Autor:
Peter Kast, Christian Stocker, Matteo Figliuzzi, Rama Ranganathan, Martin Weigt, Pierre Barrat-Charlaix, Michael Socolich, Simona Cocco, William P. Russ, Rémi Monasson, Donald Hilvert
Publikováno v:
Science, 369 (6502)
Science
Science, American Association for the Advancement of Science, 2020, 369 (6502), pp.440-445. ⟨10.1126/science.aba3304⟩
Science
Science, American Association for the Advancement of Science, 2020, 369 (6502), pp.440-445. ⟨10.1126/science.aba3304⟩
The rational design of enzymes is an important goal for both fundamental and practical reasons. Here, we describe a process to learn the constraints for specifying proteins purely from evolutionary sequence data, design and build libraries of synthet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45546e2d6b2865473d78278d7147431e
https://hdl.handle.net/20.500.11850/429569
https://hdl.handle.net/20.500.11850/429569
Autor:
Pierre Barrat-Charlaix, Matteo Figliuzzi, William P. Russ, Simona Cocco, Rama Ranganathan, Michael Socolich, Christian Stocker, Rémi Monasson, Pater Kast, Martin Weigt, Donald Hilvert
Publikováno v:
bioRxiv
The rational design of enzymes is an important goal for both fundamental and practical reasons. Here, we describe a design process in which we learn the constraints for specifying proteins purely from evolutionary sequence data, build libraries of sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2204b7299ba0da0668c14b765837901c
https://doi.org/10.1101/2020.04.01.020487
https://doi.org/10.1101/2020.04.01.020487
Publikováno v:
Synthetic Biology
The design and synthesis of novel genes and deoxyribonucleic acid (DNA) sequences is a central technique in synthetic biology. Current methods of high throughput gene synthesis use pooled oligonucleotides obtained from custom-designed DNA microarray
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5051b5b129675df67c382d709a631960
https://doi.org/10.1093/synbio/ysx008
https://doi.org/10.1093/synbio/ysx008
Autor:
Rama Ranganathan, William P. Russ, Theresa A. Kadlecek, John Kuriyan, Ian R Fallahee, Arthur Weiss, Deepti Karandur, Qingrong Yan, Neel H. Shah, Qi Wang
Publikováno v:
eLife, vol 5, iss OCTOBER2016
eLife, Vol 5 (2016)
Shah, NH; Wang, Q; Yan, Q; Karandur, D; Kadlecek, TA; Fallahee, IR; et al.(2016). An electrostatic selection mechanism controls sequential kinase signaling downstream of the T cell receptor. eLife, 5(OCTOBER2016). doi: 10.7554/eLife.20105. UCSF: Retrieved from: http://www.escholarship.org/uc/item/2st6657q
eLife
eLife, Vol 5 (2016)
Shah, NH; Wang, Q; Yan, Q; Karandur, D; Kadlecek, TA; Fallahee, IR; et al.(2016). An electrostatic selection mechanism controls sequential kinase signaling downstream of the T cell receptor. eLife, 5(OCTOBER2016). doi: 10.7554/eLife.20105. UCSF: Retrieved from: http://www.escholarship.org/uc/item/2st6657q
eLife
The sequence of events that initiates T cell signaling is dictated by the specificities and order of activation of the tyrosine kinases that signal downstream of the T cell receptor. Using a platform that combines exhaustive point-mutagenesis of pept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1210c111a3e47efd0adc7b4f51464a59
https://escholarship.org/uc/item/2st6657q
https://escholarship.org/uc/item/2st6657q