Zobrazeno 1 - 10
of 197
pro vyhledávání: '"William P. Pratt"'
Autor:
John C Trefry, Franco D Rossi, Michael V Accardi, Brandi L Dorsey, Thomas R Sprague, Suzanne E Wollen-Roberts, Joshua D Shamblin, Adrienne E Kimmel, Pamela J Glass, Lynn J Miller, Crystal W Burke, Anthony P Cardile, Darci R Smith, Sina Bavari, Simon Authier, William D Pratt, Margaret L Pitt, Farooq Nasar
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 6, p e0009424 (2021)
Most alphaviruses are mosquito-borne and can cause severe disease in humans and domesticated animals. In North America, eastern equine encephalitis virus (EEEV) is an important human pathogen with case fatality rates of 30-90%. Currently, there are n
Externí odkaz:
https://doaj.org/article/c6d1539e38da43f78f4e7ec443930c9c
EFECTOS DE LOS CAMBIOS DE MARCAS O NOMBRES: ESTUDIO EMPÍRICO SOBRE EL SECTOR DE SEGUROS EN VENEZUELA
Publikováno v:
Revista Visión Gerencial, Iss 2, Pp 219-231 (2019)
El desempeño de las organizaciones después que se han efectuado cambios de denominación o marca corporativa, ha sido documentado en la literatura del marketing y de la estrategia. Esta investigación estudia la magnitud o efecto de los cambios de
Externí odkaz:
https://doaj.org/article/2af1422edf55496694695e60e471590d
Autor:
Andrew D Haddow, Unai Perez-Sautu, Michael R Wiley, Lynn J Miller, Adrienne E Kimmel, Lucia M Principe, Suzanne E Wollen-Roberts, Joshua D Shamblin, Stephanie M Valdez, Lisa H Cazares, William D Pratt, Franco D Rossi, Luis Lugo-Roman, Sina Bavari, Gustavo F Palacios, Aysegul Nalca, Farooq Nasar, M Louise M Pitt
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 6, p e0008107 (2020)
Mosquito-borne and sexual transmission of Zika virus (ZIKV), a TORCH pathogen, recently initiated a series of large epidemics throughout the Tropics. Animal models are necessary to determine transmission risk and study pathogenesis, as well screen an
Externí odkaz:
https://doaj.org/article/98be35af1f3b4519b74544a41d1ae386
Autor:
Isaac Downs, Joshua C. Johnson, Franco Rossi, David Dyer, David L. Saunders, Nancy A. Twenhafel, Heather L. Esham, William D. Pratt, John Trefry, Elizabeth Zumbrun, Paul R. Facemire, Sara C. Johnston, Erin L. Tompkins, Nathan K. Jansen, Anna Honko, Anthony P. Cardile
Publikováno v:
Viruses, Vol 13, Iss 11, p 2297 (2021)
Ebola virus disease (EVD) is a serious global health concern because case fatality rates are approximately 50% due to recent widespread outbreaks in Africa. Well-defined nonhuman primate (NHP) models for different routes of Ebola virus exposure are n
Externí odkaz:
https://doaj.org/article/2fa118039cb14a46aec8589930dbc3a1
Autor:
Andrew D. Haddow, Aysegul Nalca, Franco D. Rossi, Lynn J. Miller, Michael R. Wiley, Unai Perez-Sautu, Samuel C. Washington, Sarah L. Norris, Suzanne E. Wollen-Roberts, Joshua D. Shamblin, Adrienne E. Kimmel, Holly A. Bloomfield, Stephanie M. Valdez, Thomas R. Sprague, Lucia M. Principe, Stephanie A. Bellanca, Stephanie S. Cinkovich, Luis Lugo-Roman, Lisa H. Cazares, William D. Pratt, Gustavo Palacios, Sina Bavari, M. Louise Pitt, Farooq Nasar
Publikováno v:
Emerging Infectious Diseases, Vol 23, Iss 8, Pp 1274-1281 (2017)
Unprotected sexual intercourse between persons residing in or traveling from regions with Zika virus transmission is a risk factor for infection. To model risk for infection after sexual intercourse, we inoculated rhesus and cynomolgus macaques with
Externí odkaz:
https://doaj.org/article/cdc9ea3b0005477f9830ccf9f4078274
Autor:
John C. Trefry, Suzanne E. Wollen, Farooq Nasar, Joshua D. Shamblin, Steven J. Kern, Jeremy J. Bearss, Michelle A. Jefferson, Taylor B. Chance, Jeffery R. Kugelman, Jason T. Ladner, Anna N. Honko, Dean J. Kobs, Morgan Q.S. Wending, Carol L. Sabourin, William D. Pratt, Gustavo F. Palacios, M. Louise M. Pitt
Publikováno v:
Viruses, Vol 7, Iss 12, Pp 6739-6754 (2015)
Recent experimentation with the variants of the Ebola virus that differ in the glycoprotein’s poly-uridine site, which dictates the form of glycoprotein produced through a transcriptional stutter, has resulted in questions regarding the pathogenici
Externí odkaz:
https://doaj.org/article/d9b9d59060924f9582b8a27951f2ee10
Autor:
Isaac L. Downs, Carl I. Shaia, Xiankun Zeng, Joshua C. Johnson, Lisa Hensley, David L. Saunders, Franco Rossi, Kathleen A. Cashman, Heather L. Esham, Melissa K. Gregory, William D. Pratt, John C. Trefry, Kyle A. Everson, Charles B. Larcom, Arthur C. Okwesili, Anthony P. Cardile, Anna Honko
Publikováno v:
Viruses, Vol 12, Iss 6, p 593 (2020)
Lassa virus (LASV), an arenavirus causing Lassa fever, is endemic to West Africa with up to 300,000 cases and between 5000 and 10,000 deaths per year. Rarely seen in the United States, Lassa virus is a CDC category A biological agent inasmuch deliber
Externí odkaz:
https://doaj.org/article/d1ff1ce80e4b46f38710d04a676990a9
Autor:
Travis K. Warren, John C. Trefry, Shannon T. Marko, Taylor B. Chance, Jay B. Wells, William D. Pratt, Joshua C. Johnson, Eric M. Mucker, Sarah L. Norris, Mark Chappell, John M. Dye, Anna N. Honko
Publikováno v:
Viruses, Vol 6, Iss 11, Pp 4666-4682 (2014)
Multiple products are being developed for use against filoviral infections. Efficacy for these products will likely be demonstrated in nonhuman primate models of filoviral disease to satisfy licensure requirements under the Animal Rule, or to supplem
Externí odkaz:
https://doaj.org/article/6b3e7d2e0c36400682621e8e0610855c
Autor:
Aarif Ahsan, Susmita G. Ramanand, Ingrid L. Bergin, Lilli Zhao, Christopher E. Whitehead, Alnawaz Rehemtulla, Dipankar Ray, William B. Pratt, Theodore S. Lawrence, Mukesh K. Nyati
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 2, Pp 105-114 (2014)
We have recently synthesized a peptide called Disruptin, which comprised the SVDNPHVC segment of the epidermal growth factor receptor (EGFR) that inhibits binding of heat shock protein 90 (Hsp90) to the EGFR and EGF-dependent EGFR dimerization to cau
Externí odkaz:
https://doaj.org/article/de03aba4996c47cda6a36b9579c2953c
Autor:
Aarif Ahsan, Susmita G. Ramanand, Christopher Whitehead, Susan M. Hiniker, Alnawaz Rehemtulla, William B. Pratt, Shruti Jolly, Christopher Gouveia, Kristy Truong, Carter Van Waes, Dipankar Ray, Theodore S. Lawrence, Mukesh K. Nyati
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 8, Pp 670-677 (2012)
The epidermal growth factor receptor (EGFR) has been targeted for inhibition using tyrosine kinase inhibitors and monoclonal antibodies, with improvement in outcome in subsets of patients with head and neck, lung, and colorectal carcinomas. We have p
Externí odkaz:
https://doaj.org/article/59e14957f98643cfb68c348498f5b062