Zobrazeno 1 - 10
of 47
pro vyhledávání: '"William P. Dubinsky"'
Publikováno v:
Journal of Analytical Sciences, Methods and Instrumentation. :54-61
Identification and quantification of low abundance growth factors and regulators in complex biological samples still present a challenging task in analytical biochemistry. Immunoassays are often used for such purpose but immunoassays face limitation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6654dfb37ad85cc631d06752eb61a2a
https://doi.org/10.4236/jasmi.2013.31006
https://doi.org/10.4236/jasmi.2013.31006
Autor:
Geetu Saxena, Perry E. Bickel, Lisa Hahner, John L. McAfee, Chaofeng Yang, Vihang A. Narkar, Christine M. Kusminski, Kathleen Hoch, Violeta I. Gallardo-Montejano, William P. Dubinsky
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Dysfunctional cellular lipid metabolism contributes to common chronic human diseases, including type 2 diabetes, obesity, fatty liver disease and diabetic cardiomyopathy. How cells balance lipid storage and mitochondrial oxidative capacity is poorly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6db8556126f54d6b2ce049aeb27de798
http://europepmc.org/articles/PMC4999519
http://europepmc.org/articles/PMC4999519
Publikováno v:
Clinics in Laboratory Medicine. 29:71-85
Proteomic analyses by mass spectrometry are propelling the field of medical diagnostics forward at unprecedented rates because of its ability reliably to identify proteins that are at the femtomole level in concentration. These advancements have also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3963dd66de8538996a82ca9a4c4f6bd
https://doi.org/10.1016/j.cll.2009.01.004
https://doi.org/10.1016/j.cll.2009.01.004
Publikováno v:
American Journal of Nephrology. 30:450-458
Background: Urine contains serum proteins filtered by the glomerulus or secreted by the renal tubules and proteins produced locally by the urinary tract. Proteomic analysis of urine holds the potential as a noninvasive means of studying or monitoring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbe2999c118e3e2295df0d355a02de37
https://doi.org/10.1159/000242430
https://doi.org/10.1159/000242430
Publikováno v:
Neurogastroenterology & Motility. 2:209-215
The contractile activities of the lower esophageal sphincter (LES), esophageal body smooth muscle (SM), and esophageal body striated muscle (ST) of the opossum differ in their dependence on oxygen. One possible explanation for this difference in oxyg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d661d5539b95d12ec17597347b811f1
https://doi.org/10.1111/j.1365-2982.1990.tb00027.x
https://doi.org/10.1111/j.1365-2982.1990.tb00027.x
Autor:
John B. Redell, Anthony N. Moore, Guy L. Clifton, William P. Dubinsky, Alex B. Valadka, Robert T. Funk, Pramod K. Dash, Robert Levine, John W. Crommett, Georgene W. Hergenroeder
Publikováno v:
Journal of Neurotrauma. 25:79-93
Brain injury biomarkers may have clinical utility in stratifying injury severity level, predicting adverse secondary events or outcomes, and monitoring the effectiveness of therapeutic interventions. As a biomarker source, serum offers several advant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::546dc4214b0de22a298a491374826921
https://doi.org/10.1089/neu.2007.0386
https://doi.org/10.1089/neu.2007.0386
Autor:
Cynthia Edwards, Otilia Mayorga-Wark, Charles F. Streckfus, Lenora Bigler, William P. Dubinsky, Daniel Arreola
Publikováno v:
Cancer Investigation. 26:159-167
Objective: The objective of this study was to determine if protein-by-products secondary to cancer related oncogenes appear in the saliva of breast cancer patients. Methods: Three pooled (n = 10 subjects/pool) stimulated whole saliva specimens from w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16d017b4304cd7ee99dd23ab5c440206
https://doi.org/10.1080/07357900701783883
https://doi.org/10.1080/07357900701783883
Publikováno v:
Journal of Biological Chemistry. 281:9101-9109
Nitric oxide (NO) participates in a variety of physiologic and pathophysiologic processes in diverse tissues, including the kidney. Although mechanisms for cytokine induction of inducible nitric-oxide synthase (iNOS) have been increasingly clarified,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12bc1199371e6de41e3e289f72e01b59
https://doi.org/10.1074/jbc.m511049200
https://doi.org/10.1074/jbc.m511049200
Autor:
Zhiqiang An, Ming Fa, Anneliese Gonzalez, Hui Deng, William P. Dubinsky, Allison Oberholtzer, Ningyan Zhang, Randall J. Brezski, Xuejun Fan, Robert Jordan, William R. Strohl
Publikováno v:
Breast Cancer Research : BCR
Introduction Recent studies reported that human IgG antibodies are susceptible to specific proteolytic cleavage in their lower hinge region, and the hinge cleavage results in a loss of Fc-mediated effector functions. Trastuzumab is a humanized IgG1 t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e834edcf59f822d644b26a3d2c4f6512
https://doi.org/10.1186/bcr3240
https://doi.org/10.1186/bcr3240
Publikováno v:
American Journal of Physiology-Cell Physiology. 265:C541-C547
We have previously demonstrated that a synthetic peptide composed of the first 22 amino acids from the NH2-terminus of the Shaker B K+ channel protein deactivates a voltage-dependent K+ channel present in basolateral membrane of Necturus small intest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a67b13a3c25f20ba206a0a5802d3b8
https://doi.org/10.1152/ajpcell.1993.265.2.c541
https://doi.org/10.1152/ajpcell.1993.265.2.c541