Zobrazeno 1 - 10
of 18
pro vyhledávání: '"William P, Swaney"'
Autor:
Stefan Fischer, Callum Duffield, William T. Swaney, Rhiannon L. Bolton, Amanda J. Davidson, Jane L. Hurst, Paula Stockley
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract Relationships between adult females are fundamental to understanding diversity in animal social systems. While cooperative relationships between kin are known to promote fitness benefits, the proximate mechanisms underlying this are not well
Externí odkaz:
https://doaj.org/article/d0a0b3f04f27436a9d6a8546629850f3
Publikováno v:
Royal Society Open Science, Vol 11, Iss 5 (2024)
For social groups to form and be stable over time, animals must develop strategies to cope with conflict among group members. Animals may behave submissively either by fleeing from an aggressor, or by signalling submission. The use of these two submi
Externí odkaz:
https://doaj.org/article/3b1e235605e34f6984ec135c29240c60
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 12, Pp 2393-2398 (2015)
Studies of human reverse cholesterol transport require intravenous infusion of cholesterol tracers. Because insoluble lipids may pose risk and because it is desirable to have consistent doses of defined composition available over many months, we inve
Externí odkaz:
https://doaj.org/article/5c300709b58e4a09861c9e0ea3cf9c4e
Publikováno v:
Journal of Lipid Research. 56:2393-2398
Studies of human reverse cholesterol transport require intravenous infusion of cholesterol tracers. Because insoluble lipids may pose risk and because it is desirable to have consistent doses of defined composition available over many months, we inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bc9528149a47c70995ec669ae784a1e
https://doi.org/10.1194/jlr.d061762
https://doi.org/10.1194/jlr.d061762
Autor:
John A. Barranger, Trina Mohney, Margaret Beeler, Erin Rice, Sherrie Scheirer‐Fochler, Edward D. Ball, Nobuaki Takiyama, Alfred B. Bahnson, William P. Swaney
Publikováno v:
European Journal of Haematology. 61:1-6
Gaucher disease is an excellent candidate for gene therapy by transduction of hematopoitic stem cells. In this study, we compared methods which allow an increase in transfer of the glucocerebrosidase gene to human hematopoietic progenitor cells. Seve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b23ea382669e9c6cf660cb27ce2c2a1
https://doi.org/10.1111/j.1600-0609.1998.tb01053.x
https://doi.org/10.1111/j.1600-0609.1998.tb01053.x
Autor:
Paul V. Woolley, Susanne M. Gollin, Waheeb Riskalla, Sydney Finkelstein, David F. Stefanik, Laila Riskalla, William P. Swaney, Larry Weisenthal, Robert J. McKenna
Publikováno v:
Molecular Diagnosis. 5:179-190
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8a60824620648af47133c917bb1016a
https://doi.org/10.2165/00066982-200005030-00003
https://doi.org/10.2165/00066982-200005030-00003
Publikováno v:
Neurochemical Research. 24:601-615
The work summarized in this paper used animal and cell culture models systems to develop gene therapy approaches for the lysosomal storage disorders. The results have provided the scientific basis for a clinical trial of gene transfer to hematopoieti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3201cfcdf77fd68e9a8a542384ecf0d
https://doi.org/10.1023/a:1022548232735
https://doi.org/10.1023/a:1022548232735
Autor:
S. Lucot, William P. Swaney, C. Sansieri, S. Scheirer-Fochler, T. Mohney, J. Lancia, John A. Barranger, Edward D. Ball, Alfred B. Bahnson, Nobuaki Takiyama, James T. Dunigan, Erin Rice, M. Beeler
Publikováno v:
Baillière's Clinical Haematology. 10:765-778
Transfer of the gene coding for glucocerebrosidase (GC) via a retroviral vector (MFG-GC) to haematopoietic progenitors results in engraftment and life-long expression of the human protein at high levels in transplanted mice. Studies of human CD34 cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84869dae80a6495512d74ff13916ebc2
https://doi.org/10.1016/s0950-3536(97)80039-x
https://doi.org/10.1016/s0950-3536(97)80039-x
Publikováno v:
Genetic Modification of Hematopoietic Stem Cells ISBN: 9781588299802
Successful retroviral gene transfer into hematopoietic cells has been demonstrated in a number of small and large animal models and clinical trials. However, severe adverse events related to insertional muta-genesis in a recent clinical trial for X-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a49a822a08c4f4992949ce9b63f58891
https://doi.org/10.1007/978-1-59745-409-4_14
https://doi.org/10.1007/978-1-59745-409-4_14
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 506
Successful retroviral gene transfer into hematopoietic cells has been demonstrated in a number of small and large animal models and clinical trials. However, severe adverse events related to insertional muta-genesis in a recent clinical trial for X-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a740e14fff4e331d1de190f3c3ba7cc8
https://pubmed.ncbi.nlm.nih.gov/19110628
https://pubmed.ncbi.nlm.nih.gov/19110628