Zobrazeno 1 - 10
of 277
pro vyhledávání: '"William P, Hanage"'
Autor:
Xueting Qiu, Lesley McGee, Laura L Hammitt, Lindsay R. Grant, Katherine L. O’Brien, William P. Hanage, Marc Lipsitch
Publikováno v:
mBio, Vol 15, Iss 10 (2024)
ABSTRACT After introducing pneumococcal conjugate vaccines (PCVs), serotype replacement occurred in Streptococcus pneumoniae. Predicting which pneumococcal strains will become common in carriage after vaccination can enhance vaccine design, public he
Externí odkaz:
https://doaj.org/article/e21b2fdcb52c46b4aaddb515700cc6a8
Autor:
William P. Hanage
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-3 (2024)
We have never known more about the genetic variation that characterizes life on earth, which is stored in ever-growing databases, many of which are publicly accessible. Yet, an accessible database does not mean that information is readily usable or i
Externí odkaz:
https://doaj.org/article/f71cfd4b570d415990d5c11d63572947
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Researchers and policymakers have proposed systems to detect novel pathogens earlier than existing surveillance systems by monitoring samples from hospital patients, wastewater, and air travel, in order to mitigate future pandemics. How much
Externí odkaz:
https://doaj.org/article/460a3e7aa44c43a98882186b110252b9
Autor:
Madikay Senghore, Hannah Read, Priyali Oza, Sarah Johnson, Hemanoel Passarelli-Araujo, Bradford P. Taylor, Stephen Ashley, Alex Grey, Alanna Callendrello, Robyn Lee, Matthew R. Goddard, Thomas Lumley, William P. Hanage, Siouxsie Wiles
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Identifying and interrupting transmission chains is important for controlling infectious diseases. One way to identify transmission pairs – two hosts in which infection was transmitted from one to the other – is using the variation of th
Externí odkaz:
https://doaj.org/article/7dfe9fd9e7ae47ab90fd24eba73981f1
Autor:
Victoria Overbeck, Bradford P. Taylor, Jacquelyn Turcinovic, Xueting Qiu, Beau Schaeffer, Scott Seitz, Scott R. Curry, William P. Hanage, John H. Connor, Krutika Kuppalli
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e23699- (2024)
Background: Immunocompromised patients receiving B-cell-depleting therapies are at increased risk of persistent SARS-CoV-2 infection, with many experiencing fatal outcomes. We report a successful outcome in a patient with rheumatoid arthritis (RA) on
Externí odkaz:
https://doaj.org/article/9d0297be99844833b7bca6b7f072d815
Autor:
Jasmijn A. Baaijens, Alessandro Zulli, Isabel M. Ott, Ioanna Nika, Mart J. van der Lugt, Mary E. Petrone, Tara Alpert, Joseph R. Fauver, Chaney C. Kalinich, Chantal B. F. Vogels, Mallery I. Breban, Claire Duvallet, Kyle A. McElroy, Newsha Ghaeli, Maxim Imakaev, Malaika F. Mckenzie-Bennett, Keith Robison, Alex Plocik, Rebecca Schilling, Martha Pierson, Rebecca Littlefield, Michelle L. Spencer, Birgitte B. Simen, Yale SARS-CoV-2 Genomic Surveillance Initiative, William P. Hanage, Nathan D. Grubaugh, Jordan Peccia, Michael Baym
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-20 (2022)
Abstract Effectively monitoring the spread of SARS-CoV-2 mutants is essential to efforts to counter the ongoing pandemic. Predicting lineage abundance from wastewater, however, is technically challenging. We show that by sequencing SARS-CoV-2 RNA in
Externí odkaz:
https://doaj.org/article/fc8864066ac8466fa436697afeaf32ee
Autor:
Mary E. Petrone, Jessica E. Rothman, Mallery I. Breban, Isabel M. Ott, Alexis Russell, Erica Lasek-Nesselquist, Hamada Badr, Kevin Kelly, Greg Omerza, Nicholas Renzette, Anne E. Watkins, Chaney C. Kalinich, Tara Alpert, Anderson F. Brito, Rebecca Earnest, Irina R. Tikhonova, Christopher Castaldi, John P. Kelly, Matthew Shudt, Jonathan Plitnick, Erasmus Schneider, Steven Murphy, Caleb Neal, Eva Laszlo, Ahmad Altajar, Claire Pearson, Anthony Muyombwe, Randy Downing, Jafar Razeq, Linda Niccolai, Madeline S. Wilson, Margaret L. Anderson, Jianhui Wang, Chen Liu, Pei Hui, Shrikant Mane, Bradford P. Taylor, William P. Hanage, Marie L. Landry, David R. Peaper, Kaya Bilguvar, Joseph R. Fauver, Chantal B. F. Vogels, Lauren M. Gardner, Virginia E. Pitzer, Kirsten St. George, Mark D. Adams, Nathan D. Grubaugh
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
The Alpha and Iota SARS-CoV-2 variants exhibit up to 50% greater transmissibility compared to other circulating variants in Connecticut in early 2021.
Externí odkaz:
https://doaj.org/article/028dafa93b3d4984824dfc01b20e2df0
Publikováno v:
The Lancet Regional Health. Americas, Vol 16, Iss , Pp 100384- (2022)
Summary: Background: Scant research, including in the United States, has quantified relationships between the political ideologies of elected representatives and COVID-19 outcomes among their constituents. Methods: We analyzed observational cross-sec
Externí odkaz:
https://doaj.org/article/c8131b0012b24c7ab46b5437a2005525
Autor:
Jacquelyn Turcinovic, Kayla Kuhfeldt, Madison Sullivan, Lena Landaverde, Judy T. Platt, Lynn Doucette-Stamm, William P. Hanage, Davidson H. Hamer, Catherine Klapperich, Hannah E. Landsberg, John H. Connor
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105337- (2022)
Summary: Contact tracing and genomic data, approaches often used separately, have both been important tools in understanding the nature of SARS-CoV-2 transmission. Linked analysis of contact tracing and sequence relatedness of SARS-CoV-2 genomes from
Externí odkaz:
https://doaj.org/article/2e56e3922e554640898d496531550dcb
Autor:
An-Ni Zhang, Jeffry M. Gaston, Chengzhen L. Dai, Shijie Zhao, Mathilde Poyet, Mathieu Groussin, Xiaole Yin, Li-Guan Li, Mark C. M. van Loosdrecht, Edward Topp, Michael R. Gillings, William P. Hanage, James M. Tiedje, Katya Moniz, Eric J. Alm, Tong Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Antibiotic resistance genes are common but not all are of high risk to human health. Here, the authors develop an omics-based framework for ranking genes by risk that incorporates level of enrichment in human associated environments, gene mobility, a
Externí odkaz:
https://doaj.org/article/00e1d75466c746b5b7176e663387fb5b