Zobrazeno 1 - 10
of 73
pro vyhledávání: '"William O. Rogers"'
Autor:
Dysoley Lek, Agus Rachmat, Dustin Harrison, Geoffrey Chin, Suwanna Chaoratanakawee, David Saunders, Didier Menard, William O. Rogers
Publikováno v:
Malaria Journal, Vol 21, Iss 1, Pp 1-17 (2022)
Abstract Background Anti-malarial resistance remains an important public health challenge in Cambodia. The effectiveness of three therapies for uncomplicated falciparum malaria was evaluated in Oddar Meanchey province in Northern Cambodia from 2009 t
Externí odkaz:
https://doaj.org/article/e2910843bfe04e7b95aafa4cbbf51a08
Autor:
Kwadwo A. Koram, Carla Proietti, Philip L. Felgner, Thomas L. Richie, Ben Gyan, Daniel Dodoo, Lutz Krause, Angela Trieu, William O. Rogers, Peter D. Crompton, Denise L. Doolan
Publikováno v:
Molecular & Cellular Proteomics. 19:101-113
A large body of evidence supports the role of antibodies directed against the Plasmodium spp. parasite in the development of naturally acquired immunity to malaria, however an antigen signature capable of predicting protective immunity against Plasmo
Autor:
Christian M Parobek, Jeffrey A Bailey, Nicholas J Hathaway, Duong Socheat, William O Rogers, Jonathan J Juliano
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 4, p e2796 (2014)
Although Plasmodium vivax is a leading cause of malaria around the world, only a handful of vivax antigens are being studied for vaccine development. Here, we investigated genetic signatures of selection and geospatial genetic diversity of two leadin
Externí odkaz:
https://doaj.org/article/0aed1e4227d2460fb3326513fa370190
Autor:
Anita Ghansah, Kirk A Rockett, Taane G Clark, Michael D Wilson, Kwadwo A Koram, Abraham R Oduro, Lucas Amenga-Etego, Thomas Anyorigiya, Abraham Hodgson, Paul Milligan, William O Rogers, Dominic P Kwiatkowski
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34565 (2012)
Haemoglobin S (HbS) and C (HbC) are variants of the HBB gene which both protect against malaria. It is not clear, however, how these two alleles have evolved in the West African countries where they co-exist at high frequencies. Here we use haplotypi
Externí odkaz:
https://doaj.org/article/2c9303197c244f3e828324aa3579f08e
Autor:
Sumiti Vinayak, Md Tauqeer Alam, Tonya Mixson-Hayden, Andrea M McCollum, Rithy Sem, Naman K Shah, Pharath Lim, Sinuon Muth, William O Rogers, Thierry Fandeur, John W Barnwell, Ananias A Escalante, Chansuda Wongsrichanalai, Frederick Ariey, Steven R Meshnick, Venkatachalam Udhayakumar
Publikováno v:
PLoS Pathogens, Vol 6, Iss 3, p e1000830 (2010)
The Thailand-Cambodia border is the epicenter for drug-resistant falciparum malaria. Previous studies have shown that chloroquine (CQ) and pyrimethamine resistance originated in this region and eventually spread to other Asian countries and Africa. H
Externí odkaz:
https://doaj.org/article/c70395b010c640bf8391bea1cf1ad3f5
Autor:
Carla, Proietti, Lutz, Krause, Angela, Trieu, Daniel, Dodoo, Ben, Gyan, Kwadwo A, Koram, William O, Rogers, Thomas L, Richie, Peter D, Crompton, Philip L, Felgner, Denise L, Doolan
Publikováno v:
Molecular & Cellular Proteomics : MCP
We have established a predictive modelling framework to systematically analyze IgG antibody responses against a large panel of P. falciparum-specific antigens and identify a predictive signature of naturally acquired immunity to malaria. Our results
Autor:
Ratawan Ubalee, Chansuda Wongsrichanalai, Jetsumon Sattabongkot, Jaymin C. Patel, Sinuon Muth, Jessica T. Lin, Anthony L. Schuster, William O. Rogers, Jonathan J. Juliano, Oksana Kharabora
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 88:1116-1123
Plasmodium vivax accounts for an increasing fraction of malaria infections in Thailand and Cambodia. We compared P. vivax genetic complexity and antimalarial resistance patterns in the two countries. Use of a heteroduplex tracking assay targeting the
Autor:
Kalpana Gowda, Mark Gold, J. Kevin Baird, Anita Kumar, Sanjai Kumar, Stephen L. Hoffman, Robert W. Gwadz, Joao C. Aguiar, John A. Tine, Walter R. Weiss, William O. Rogers
A nonhuman primate model for malaria vaccine development allowing reliable, stringent sporozoite challenge and evaluation of both cellular and antibody responses is needed. We therefore constructed a multicomponent, multistage DNA vaccine for the sim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bfbbfa5496b61a20b5c181468e17016
https://doi.org/10.1128/iai.69.9.5565-5572.2001
https://doi.org/10.1128/iai.69.9.5565-5572.2001
Autor:
Malcolm E. Molyneux, Dominic P. Kwiatkowski, Fatou Sisay-Joof, Thomas N. Williams, Kasturi Haldar, Anita Ghansah, Kwadwo A. Koram, Andrew E. Fry, Muminatou Jallow, William O. Rogers, Mahamadou Diakite, Kevin Marsh, Kirk A. Rockett, Michael J. Griffiths, Susana Campino, Terrie Taylor, Margaret Pinder, Sarah Auburn, Anna Richardson, Norbert Peshu, Abraham Oduro
Functional studies have demonstrated an interaction between the stimulatory G protein alpha subunit (G-alpha-s) and the malaria parasite at a cellular level. Obstruction of signal transduction via the erythrocyte G-alpha-s subunit reduced invasion by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a99e997c3506e6019313e52bee33132e
https://ora.ox.ac.uk/objects/uuid:45f8f2fa-1e8e-4413-ae53-7bd92183a8d9
https://ora.ox.ac.uk/objects/uuid:45f8f2fa-1e8e-4413-ae53-7bd92183a8d9
Autor:
Michael D. Wilson, Abraham Oduro, Kirk A. Rockett, Lucas Amenga-Etego, Anita Ghansah, Taane G. Clark, Paul Milligan, Thomas Anyorigiya, Dominic P. Kwiatkowski, Kwadwo A. Koram, Abraham Hodgson, William O. Rogers
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 4, p e34565 (2012)
PLoS ONE, Vol 7, Iss 4, p e34565 (2012)
BACKGROUND: Haemoglobin S (HbS) and C (HbC) are variants of the HBB gene which both protect against malaria. It is not clear, however, how these two alleles have evolved in the West African countries where they co-exist at high frequencies. Here we u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e4c4eeca66022ae1dba323cd2aaa21
https://ora.ox.ac.uk/objects/uuid:3e299bcd-3ce8-4ef1-ae47-daf9c4323afd
https://ora.ox.ac.uk/objects/uuid:3e299bcd-3ce8-4ef1-ae47-daf9c4323afd