Zobrazeno 1 - 10
of 49
pro vyhledávání: '"William O Cepurna"'
Autor:
Shandiz Tehrani, Lauren Davis, William O Cepurna, Tiffany E Choe, Diana C Lozano, Ashley Monfared, Lauren Cooper, Joshua Cheng, Elaine C Johnson, John C Morrison
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0167364 (2016)
Glaucomatous axon injury occurs at the level of the optic nerve head (ONH) in response to uncontrolled intraocular pressure (IOP). The temporal response of ONH astrocytes (glial cells responsible for axonal support) to elevated IOP remains unknown. H
Externí odkaz:
https://doaj.org/article/4ca1ab736ffe460785f41277a95d4e77
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose We previously reported increased expression of cell proliferation and Jak-Stat pathway-related genes in chronic experimental glaucoma model optic nerve heads (ONH) with early, mild injury. Here, we confirm these observations by localizing, id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5867a2e38d7783b8548383a721a5bcd8
http://europepmc.org/articles/PMC6402265
http://europepmc.org/articles/PMC6402265
Autor:
John C. Morrison, Ruikang K. Wang, William O. Cepurna, Jingjiang Xu, Yuandong Li, Shaozhen Song
Publikováno v:
Microvascular Research. 121:37-45
We report the development of a 1300 nm swept-source optical coherence tomography (SS-OCT) system specifically designed to perform OCT imaging and optical microangiography (OMAG) in rat eyes in vivo and its use in evaluating the effects of intraocular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8784f019f01a100de51817fa999a170
https://doi.org/10.1016/j.mvr.2018.09.003
https://doi.org/10.1016/j.mvr.2018.09.003
Autor:
Bingjie Wang, Tristan T. Hormel, Yali Jia, John C. Morrison, Xiang Wei, William O. Cepurna, Shaohua Pi
Publikováno v:
Proc Natl Acad Sci U S A
Assessing oxygen saturation (sO 2 ) remains challenging but is nonetheless necessary for understanding retinal metabolism. We and others previously achieved oximetry on major retinal vessels and measured the total retinal oxygen metabolic rate in rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31e1ec43f359e3c588858062cb658700
https://pubmed.ncbi.nlm.nih.gov/32554605
https://pubmed.ncbi.nlm.nih.gov/32554605
Autor:
William O. Cepurna, Diana C Lozano, Kate E. Keller, Jay Ian Phillips, Julie A. Saugstad, Devin M. Gattey, Hari Jayaram, Tiffany E. Choe, Elaine C. Johnson, John C. Morrison
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose MicroRNAs (miRNAs) are small, endogenous noncoding RNAs that have been detected in human aqueous humor (AH). Prior studies have pooled samples to obtain sufficient quantities for analysis or used next-generation sequencing. Here, we used PCR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd47a9d2d645ce4f3b95e3a94e784a66
http://europepmc.org/articles/PMC5460954
http://europepmc.org/articles/PMC5460954
Autor:
Yali Jia, David Huang, John C. Morrison, Shaohua Pi, Tristan T. Hormel, William O. Cepurna, Xiang Wei, Acner Camino
Defocusing, vignetting, and bulk motion degrade the image quality of optical coherence tomography angiography (OCTA) more significantly than structural OCT. The assessment of focus, alignment conditions, and stability of imaging subjects in commercia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26cd6056e434566575e0e06a88600b1f
https://europepmc.org/articles/PMC7188388/
https://europepmc.org/articles/PMC7188388/
Autor:
Elaine C. Johnson, Claude F. Burgoyne, Marta Pazos, William O. Cepurna, John C. Morrison, Hongli Yang, Stuart K. Gardiner
Publikováno v:
Experimental Eye Research. 145:173-186
PURPOSE: To characterize early optic nerve head (ONH) structural change in rat experimental glaucoma (EG). METHODS: Unilateral intraocular pressure (IOP) elevation was induced in Brown Norway rats by hypertonic saline injection into the episcleral ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07268a097d9bb3f3745c800aa4d41c3b
https://doi.org/10.1016/j.exer.2015.10.014
https://doi.org/10.1016/j.exer.2015.10.014
Publikováno v:
Opt Lett
In vivo high-resolution images are the most direct way to understand retinal function and diseases. Here we report the use of visible-light optical coherence tomography with volumetric registration and averaging to achieve cellular-level retinal stru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::316f7c7b3d655016c8e4c75fe6a45cc3
https://doi.org/10.1364/ol.386454
https://doi.org/10.1364/ol.386454
Autor:
David Huang, William O. Cepurna, Acner Camino, Joseph M. Simonett, Xiang Wei, Shaohua Pi, Yali Jia, John C. Morrison
Visible light optical coherence tomography (vis-OCT) is an emerging label-free and high-resolution 3-dimensional imaging technique that can provide retinal oximetry, angiography, and flowmetry in one modality. In this paper, we studied the organizati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d73b9dbd351e5a8a0a5729818fbfa794
https://europepmc.org/articles/PMC6238898/
https://europepmc.org/articles/PMC6238898/
Autor:
William O. Cepurna, Shaohua Pi, Xiang Wei, Acner Camino, Yali Jia, John C. Morrison, David Huang
Publikováno v:
Optics letters. 43(9)
Phase-based optical coherence tomography (OCT), such as OCT angiography (OCTA) and Doppler OCT, is sensitive to the confounding phase shift introduced by subject bulk motion. Traditional bulk motion compensation methods are limited by their accuracy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5e96b1fdb9a43bfe6eac44bddf3de8
https://pubmed.ncbi.nlm.nih.gov/29714790
https://pubmed.ncbi.nlm.nih.gov/29714790