Zobrazeno 1 - 10
of 255
pro vyhledávání: '"William N. William"'
Autor:
Xinyi Zhang, Frederico O. Gleber‐Netto, Shidan Wang, Roberta Rayra Martins‐Chaves, Ricardo Santiago Gomez, Nadarajah Vigneswaran, Arunangshu Sarkar, William N. William Jr, Vassiliki Papadimitrakopoulou, Michelle Williams, Diana Bell, Doreen Palsgrove, Justin Bishop, John V. Heymach, Ann M. Gillenwater, Jeffrey N. Myers, Renata Ferrarotto, Scott M. Lippman, Curtis Rg Pickering, Guanghua Xiao
Publikováno v:
Cancer Medicine, Vol 12, Iss 6, Pp 7508-7518 (2023)
Abstract Background Oral leukoplakia (OL) is associated with an increased risk for oral cancer (OC) development. Prediction of OL cancer progression may contribute to decreased OC morbidity and mortality by favoring early intervention. Current OL pro
Externí odkaz:
https://doaj.org/article/f1684d19b6ad4c94aa6119b3cd2b7657
Autor:
Gustavo Gössling, Taiane F. Rebelatto, Cynthia Villarreal-Garza, Ana S. Ferrigno, Denisse Bretel, Raul Sala, Juliana Giacomazzi, William N. William, Gustavo Werutsky
Publikováno v:
Current Oncology, Vol 30, Iss 1, Pp 653-662 (2023)
In Latin America and the Caribbean (LAC), progress has been made in some national and regional cancer control initiatives, which have proved useful in reducing diagnostic and treatment initiation delays. However, there are still significant gaps, inc
Externí odkaz:
https://doaj.org/article/74e5cd7f40c749d4be147d1c222d3c07
Autor:
Aline B. Lara Gongora, Gustavo Werutsky, Denis L. Jardim, Angelica Nogueira-Rodrigues, Carlos H. Barrios, Clarissa Mathias, Fernando Maluf, Rachel Riechelmann, Maurício Fraga, Henry Gomes, William N. William, Camilla A. F. Yamada, Gilberto de Castro Jr, Daniela D. Rosa, Andreia C. de Melo, Raul Sala, Eva Bustamante, Denisse Bretel, Oscar Arrieta, Andrés F. Cardona, Diogo A. Bastos
Publikováno v:
JCO Global Oncology, Vol , Iss 7, Pp 649-658 (2021)
PURPOSECOVID-19 has affected cancer care worldwide. Clinical trials are an important alternative for the treatment of oncologic patients, especially in Latin America, where trials can be the only opportunity for some of them to access novel and, some
Externí odkaz:
https://doaj.org/article/c6436c3390d04fb48eb100f0ab3f6c2c
Autor:
Ming Chen, Runzhe Chen, Ying Jin, Jun Li, Xin Hu, Jiexin Zhang, Junya Fujimoto, Shawna M. Hubert, Carl M. Gay, Bo Zhu, Yanhua Tian, Nicholas McGranahan, Won-Chul Lee, Julie George, Xiao Hu, Yamei Chen, Meijuan Wu, Carmen Behrens, Chi-Wan Chow, Hoa H. N. Pham, Junya Fukuoka, Jia Wu, Edwin Roger Parra, Latasha D. Little, Curtis Gumbs, Xingzhi Song, Chang-Jiun Wu, Lixia Diao, Qi Wang, Robert Cardnell, Jianhua Zhang, Jing Wang, Xiuning Le, Don L. Gibbons, John V. Heymach, J. Jack Lee, William N. William, Chao Cheng, Bonnie Glisson, Ignacio Wistuba, P. Andrew Futreal, Roman K. Thomas, Alexandre Reuben, Lauren A. Byers, Jianjun Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Small-cell lung cancer (SCLC) is an aggressive disease with limited therapeutic options. Here the authors perform an immunogenomic analysis of limited-stage SCLC, revealing a homogeneous mutational landscape, but limited T-cell infiltration and a col
Externí odkaz:
https://doaj.org/article/61c0fcf9baf94acab6feccd225cfafb0
Autor:
Tina Cascone, Annikka Weissferdt, Myrna C. B. Godoy, William N. William, Cheuk H. Leung, Heather Y. Lin, Sreyashi Basu, Shalini S. Yadav, Apar Pataer, Kyle G. Mitchell, Md Abdul Wadud Khan, Yushu Shi, Cara Haymaker, Luisa M. Solis, Edwin R. Parra, Humam Kadara, Ignacio I. Wistuba, Padmanee Sharma, James P. Allison, Nadim J. Ajami, Jennifer A. Wargo, Robert R. Jenq, Don L. Gibbons, J. Jack Lee, Stephen G. Swisher, Ara A. Vaporciyan, John V. Heymach, Boris Sepesi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Granulomatous/sarcoid-like lesions have been reported in patients treated with immune checkpoint inhibitors (ICIs). Here the authors report the occurrence of “nodal immune flare”, an apparent radiological cancer progression in the nodes character
Externí odkaz:
https://doaj.org/article/02f55269e7f9462fb8c8389a4b130848
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Preclinical data suggest that head and neck squamous cell carcinomas (HNSCC) may evade immune surveillance and induce immunosuppression. One mechanism of immune evasion involves the expression of programmed death ligand-1 (PD-L1) in tumor and immune
Externí odkaz:
https://doaj.org/article/49277bafc01c492297e65a5bd00d8067
Autor:
Rui Imamura, Ricardo F. Bento, Leandro L. Matos, William N. William Jr., Gustavo N. Marta, Aline L. F. Chaves, Gilberto de Castro Jr., Luiz P. Kowalski
Publikováno v:
International Archives of Otorhinolaryngology, Vol 25, Iss 01, Pp e150-e159 (2021)
Background With the COVID-19 pandemic, the clinical practice of physicians who work in the head and neck field in Brazil dropped dramatically. The sustained impact of the pandemic is not known. Methods An anonymous online survey was distributed to Br
Externí odkaz:
https://doaj.org/article/8ad899b8f74c49619e88e07eacbaa2a2
Autor:
Edwin R. Parra, Pamela Villalobos, Carmen Behrens, Mei Jiang, Apar Pataer, Stephen G. Swisher, William N. William, Jiexin Zhang, Jack Lee, Tina Cascone, John V. Heymach, Marie-Andrée Forget, Cara Haymaker, Chantale Bernatchez, Neda Kalhor, Annikka Weissferdt, Cesar Moran, Jianjun Zhang, Ara Vaporciyan, Don L. Gibbons, Boris Sepesi, Ignacio I. Wistuba
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-11 (2018)
Abstract Background The clinical efficacy observed with inhibitors of programed cell death 1/programed cell death ligand 1 (PD-L1/PD-1) in cancer therapy has prompted studies to characterize the immune response in several tumor types, including lung
Externí odkaz:
https://doaj.org/article/a0fbee6e3c0d4cdda806783e081be8ef
Autor:
Yu Liu, Jianjun Zhang, Lin Li, Guangliang Yin, Jianhua Zhang, Shan Zheng, Hannah Cheung, Ning Wu, Ning Lu, Xizeng Mao, Longhai Yang, Jiexin Zhang, Li Zhang, Sahil Seth, Huang Chen, Xingzhi Song, Kan Liu, Yongqiang Xie, Lina Zhou, Chuanduo Zhao, Naijun Han, Wenting Chen, Susu Zhang, Longyun Chen, Wenjun Cai, Miaozhong Shen, Ningzhi Xu, Shujun Cheng, Huanming Yang, J. Jack Lee, Arlene Correa, Junya Fujimoto, Carmen Behrens, Chi-Wan Chow, William N. William, John V. Heymach, Waun Ki Hong, Stephen Swisher, Ignacio I. Wistuba, Jun Wang, Dongmei Lin, Xiangyang Liu, P. Andrew Futreal, Yanning Gao
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Some patients present with multiple lung tumours but it is unclear whether these are metastases or individual lesions. Here, the authors use genomics techniques to demonstrate in six patients that multiple tumours have individual genetic profiles and
Externí odkaz:
https://doaj.org/article/b47899a5b32046278f07cf214de45ffc
Autor:
Tina Cascone, Cheuk H. Leung, Annikka Weissferdt, Apar Pataer, Brett W. Carter, Myrna C. B. Godoy, Hope Feldman, William N. William, Yuanxin Xi, Sreyashi Basu, Jing Jing Sun, Shalini S. Yadav, Frank R. Rojas Alvarez, Younghee Lee, Aditya K. Mishra, Lili Chen, Monika Pradhan, Haiping Guo, Ansam Sinjab, Nicolas Zhou, Marcelo V. Negrao, Xiuning Le, Carl M. Gay, Anne S. Tsao, Lauren Averett Byers, Mehmet Altan, Bonnie S. Glisson, Frank V. Fossella, Yasir Y. Elamin, George Blumenschein, Jianjun Zhang, Ferdinandos Skoulidis, Jia Wu, Reza J. Mehran, David C. Rice, Garrett L. Walsh, Wayne L. Hofstetter, Ravi Rajaram, Mara B. Antonoff, Junya Fujimoto, Luisa M. Solis, Edwin R. Parra, Cara Haymaker, Ignacio I. Wistuba, Stephen G. Swisher, Ara A. Vaporciyan, Heather Y. Lin, Jing Wang, Don L. Gibbons, J. Jack Lee, Nadim J. Ajami, Jennifer A. Wargo, James P. Allison, Padmanee Sharma, Humam Kadara, John V. Heymach, Boris Sepesi
Publikováno v:
Nature Medicine. 29:593-604
Neoadjuvant ipilimumab + nivolumab (Ipi+Nivo) and nivolumab + chemotherapy (Nivo+CT) induce greater pathologic response rates than CT alone in patients with operable non-small cell lung cancer (NSCLC). The impact of adding ipilimumab to neoadjuvant N