Zobrazeno 1 - 10
of 108
pro vyhledávání: '"William N Green"'
Autor:
Anitha P Govind, Okunola Jeyifous, Theron A Russell, Zola Yi, Aubrey V Weigel, Abhijit Ramaprasad, Luke Newell, William Ramos, Fernando M Valbuena, Jason C Casler, Jing-Zhi Yan, Benjamin S Glick, Geoffrey T Swanson, Jennifer Lippincott-Schwartz, William N Green
Publikováno v:
eLife, Vol 10 (2021)
Activity-driven changes in the neuronal surface glycoproteome are known to occur with synapse formation, plasticity, and related diseases, but their mechanistic basis and significance are unclear. Here, we observed that N-glycans on surface glycoprot
Externí odkaz:
https://doaj.org/article/00279d88468b4f06978613bb9f77744b
Autor:
Sang Hak Lee, Chaoyi Jin, En Cai, Pinghua Ge, Yuji Ishitsuka, Kai Wen Teng, Andre A de Thomaz, Duncan Nall, Murat Baday, Okunola Jeyifous, Daniel Demonte, Christopher M Dundas, Sheldon Park, Jary Y Delgado, William N Green, Paul R Selvin
Publikováno v:
eLife, Vol 6 (2017)
Externí odkaz:
https://doaj.org/article/567e1bdae8b74f92ab6285eca5d9df67
Autor:
Anitha P Govind, Yolanda F Vallejo, Jacob R Stolz, Jing-Zhi Yan, Geoffrey T Swanson, William N Green
Publikováno v:
eLife, Vol 6 (2017)
To better understand smoking cessation, we examined the actions of varenicline (Chantix) during long-term nicotine exposure. Varenicline reduced nicotine upregulation of α4β2-type nicotinic receptors (α4β2Rs) in live cells and neurons, but not fo
Externí odkaz:
https://doaj.org/article/79b29b5950784761aa0b52005dd6c5f1
Autor:
Sang Hak Lee, Chaoyi Jin, En Cai, Pinghua Ge, Yuji Ishitsuka, Kai Wen Teng, Andre A de Thomaz, Duncan Nall, Murat Baday, Okunola Jeyifous, Daniel Demonte, Christopher M Dundas, Sheldon Park, Jary Y Delgado, William N Green, Paul R Selvin
Publikováno v:
eLife, Vol 6 (2017)
Previous studies tracking AMPA receptor (AMPAR) diffusion at synapses observed a large mobile extrasynaptic AMPAR pool. Using super-resolution microscopy, we examined how fluorophore size and photostability affected AMPAR trafficking outside of, and
Externí odkaz:
https://doaj.org/article/671f3c4ec2474b219f8b84c8994f00b7
Autor:
Kevin P. Koster, William N. Green
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 16 (2024)
Externí odkaz:
https://doaj.org/article/3f2917c328bb46b79eceb5ddb652d82b
Publikováno v:
eLife, Vol 4 (2015)
Changes in glutamatergic synaptic strength in brain are dependent on AMPA-type glutamate receptor (AMPAR) recycling, which is assumed to occur through a single local pathway. In this study, we present evidence that AMPAR recycling occurs through diff
Externí odkaz:
https://doaj.org/article/9b8a3bf28cc34f62a2826252cea662c8
Autor:
Yang Cao, Huachun Liu, Shannon S. Lu, Krysten A. Jones, Anitha P. Govind, Okunola Jeyifous, Christine Q. Simmons, Negar Tabatabaei, William N. Green, Jimmy. L. Holder, Soroush Tahmasebi, Alfred L. George, Bryan C. Dickinson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Technologies capable of programmable translation activation offer strategies to develop therapeutics for diseases caused by insufficient gene expression. Here, we present “translation-activating RNAs” (taRNAs), a bifunctional RNA-based m
Externí odkaz:
https://doaj.org/article/2f3bf8fe6f5a49a79837b57f3d09a867
Autor:
Matthew Zammit, Chien-Min Kao, Hannah J. Zhang, Hsiu-Ming Tsai, Nathanial Holderman, Samuel Mitchell, Eve Tanios, Mohammed Bhuiyan, Richard Freifelder, Anna Kucharski, William N. Green, Jogeshwar Mukherjee, Chin-Tu Chen
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 21, p 15510 (2023)
Positron emission tomography (PET) radioligands that bind with high-affinity to α4β2-type nicotinic receptors (α4β2Rs) allow for in vivo investigations of the mechanisms underlying nicotine addiction and smoking cessation. Here, we investigate th
Externí odkaz:
https://doaj.org/article/529a1aeb78e440c383ad1f97ae4b8642
Autor:
Akira Yoshii, William N. Green
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 12 (2020)
Externí odkaz:
https://doaj.org/article/7c09bec816fe4bde97e9634ab82b6809
Autor:
Hannah J. Zhang, Matthew Zammit, Chien-Min Kao, Anitha P. Govind, Samuel Mitchell, Nathanial Holderman, Mohammed Bhuiyan, Richard Freifelder, Anna Kucharski, Xiaoxi Zhuang, Jogeshwar Mukherjee, Chin-Tu Chen, William N. Green
Publikováno v:
J Neurosci
A question relevant to nicotine addiction is how nicotine and other nicotinic receptor membrane-permeant ligands, such as the anti-smoking drug varenicline (Chantix), distribute in brain. Ligands, like varenicline, with high pKaand high affinity for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06f4cb8c695d85830f981fd20a41960c
https://europepmc.org/articles/PMC9838697/
https://europepmc.org/articles/PMC9838697/