Zobrazeno 1 - 10
of 102
pro vyhledávání: '"William Mansfield"'
Autor:
Céline Labouesse, Bao Xiu Tan, Chibeza C. Agley, Moritz Hofer, Alexander K. Winkel, Giuliano G. Stirparo, Hannah T. Stuart, Christophe M. Verstreken, Carla Mulas, William Mansfield, Paul Bertone, Kristian Franze, José C. R. Silva, Kevin J. Chalut
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
The independent control of substrate stiffness and tethering of extracellular matrix to substrates for mechanical signalling investigations remains challenging. Here the authors present StemBond hydrogels, with stable ECM tethering that can be varied
Externí odkaz:
https://doaj.org/article/2711320dd2f24be2b2c8cdd0355b3ae1
Autor:
Sumia A. Bageghni, Georgia A. Frentzou, Mark J. Drinkhill, William Mansfield, Dawn Coverley, Justin F. X. Ainscough
Publikováno v:
Biology Open, Vol 6, Iss 1, Pp 92-99 (2017)
Myocardial injury in mammals leads to heart failure through pathological cardiac remodelling that includes hypertrophy, fibrosis and ventricular dilatation. Central to this is inability of the mammalian cardiomyocyte to self-renew due to entering a q
Externí odkaz:
https://doaj.org/article/0d701bab6b0e4f4894c5747f311fd0b2
Autor:
Kathryn Blair, Harry G. Leitch, William Mansfield, Charles-Étienne Dumeau, Peter Humphreys, Austin G. Smith
Publikováno v:
Biology Open, Vol 1, Iss 1, Pp 58-65 (2011)
Summary The ability of cultured pluripotent cells to contribute to the germline of chimaeric animals is essential to their utility for genetic manipulation. In the three years since rat embryonic stem (ES) cells were first reported the anticipated pr
Externí odkaz:
https://doaj.org/article/e9eee9cc56e34badb117ebd5f6b31936
Autor:
Xionghui Lin, Benjamin Swedlund, Mai-Linh N. Ton, Shila Ghazanfar, Carolina Guibentif, Catherine Paulissen, Elodie Baudelet, Elise Plaindoux, Younes Achouri, Emilie Calonne, Christine Dubois, William Mansfield, Stéphane Zaffran, John C. Marioni, Francois Fuks, Berthold Göttgens, Fabienne Lescroart, Cédric Blanpain
Publikováno v:
Nature Cell Biology
Nature Cell Biology, 2022, 24 (7), pp.1114-1128. ⟨10.1038/s41556-022-00947-3⟩
Nature Cell Biology, 2022, 24 (7), pp.1114-1128. ⟨10.1038/s41556-022-00947-3⟩
The mammalian heart arises from various populations of Mesp1-expressing cardiovascular progenitors (CPs) that are specified during the early stages of gastrulation. Mesp1 is a transcription factor that acts as a master regulator of CP specification a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::290000607eadbc0a3f96b2949ab079e8
Autor:
Bao Xiu Tan, Céline Labouesse, Carla Mulas, Alexander K. Winkel, Moritz Hofer, Christophe M. Verstreken, Chibeza C. Agley, Kevin J. Chalut, José C. R. Silva, Giuliano Giuseppe Stirparo, Paul Bertone, Kristian Franze, William Mansfield, Hannah T. Stuart
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications
Nature Communications
Funder: Medical Research Council (UK) Career Development Award (G1100312/1)
Funder: Medical Research Council (UK) MR/M011089/1 Wellcome Trust-Medical Research Council core funding to the Wellcome-MRC Cambridge Stem Cell Institute
Studies of
Funder: Medical Research Council (UK) MR/M011089/1 Wellcome Trust-Medical Research Council core funding to the Wellcome-MRC Cambridge Stem Cell Institute
Studies of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79db56a2eb87774cd06d0a784eb5336e
https://www.repository.cam.ac.uk/handle/1810/329719
https://www.repository.cam.ac.uk/handle/1810/329719
Autor:
Austin Smith, Masaki Kinoshita, Sabine Dietmann, Meng Amy Li, William Mansfield, Michael Barber
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Mammalian DNA is widely modified by methylation of cytosine residues. This modification is added to DNA during early development. If methylation is prevented, the embryo dies by midgestation with multiple abnormalities. In this study we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c0eb256aba05fbc96d2e9ba37c811c
https://doi.org/10.1073/pnas.2109475118
https://doi.org/10.1073/pnas.2109475118
Autor:
Simon J. Nicol, Peter A Williams, Sue Taei, Timothy Adams, Glen Holmes, Matthieu Lengaigne, Sangaalofa Clark, William Mansfield, Inna Senina, Thomas Gorgues, Patrick Lehodey, Martin Tsamenyi, Morgane Dessert, Quentin A Hanich, Katherine Seto, Christophe E. Menkès, Beatriz Calmettes, Harriet Harden-Davies, Coral Pasisi, Chis Reid, John M. Hampton, Olivier Aumont, Alex Sen Gupta, Yoshitaka Ota, Marion Gehlen, Espen Ronneberg, Neville Smith, Graham M. Pilling, Johann D. Bell, Steven R. Hare
Publikováno v:
Nature Sustainability
Nature Sustainability, 2021, ⟨10.1038/s41893-021-00745-z⟩
Nature Sustainability (2398-9629) (Springer Science and Business Media LLC), 2021-10, Vol. 4, N. 10, P. 900-910
Nature Sustainability, Springer Nature, 2021, ⟨10.1038/s41893-021-00745-z⟩
Nature Sustainability, vol 4, iss 10
Nature Sustainability, 2021, ⟨10.1038/s41893-021-00745-z⟩
Nature Sustainability (2398-9629) (Springer Science and Business Media LLC), 2021-10, Vol. 4, N. 10, P. 900-910
Nature Sustainability, Springer Nature, 2021, ⟨10.1038/s41893-021-00745-z⟩
Nature Sustainability, vol 4, iss 10
Climate-driven redistribution of tuna threatens to disrupt the economies of Pacific Small Island Developing States (SIDS) and sustainable management of the world’s largest tuna fishery. Here we show that by 2050, under a high greenhouse gas emissio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20c2408437ce059818078ec2bbd03de7
https://hal.science/hal-03317932/file/s41893-021-00745-z.pdf
https://hal.science/hal-03317932/file/s41893-021-00745-z.pdf
Autor:
Austin Smith, Masaki Kinoshita, Sabine Dietmann, Meng Amy Li, Michael Barber, William Mansfield
Genome remethylation is essential for mammalian development but specific reasons are unclear. Here we examined embryonic stem (ES) cell fate in the absence of de novo DNA methyltransferases. We observed that ES cells deficient for both Dnmt3a and Dnm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3df881e94b1f064d6996941a02ace3d9
https://doi.org/10.1101/2020.12.20.423404
https://doi.org/10.1101/2020.12.20.423404
Autor:
Viviane Souza Rosa, Lorenzo Carlo Orietti, Marta N. Shahbazi, Christos Kyprianou, Francesco Antonica, Magdalena Zernicka-Goetz, Henrique Marques-Souza, William Mansfield
Publikováno v:
Stem Cell Reports
Summary Mammalian embryogenesis is a paradigm of regulative development as mouse embryos show plasticity in the regulation of cell fate, cell number, and tissue morphogenesis. However, the mechanisms behind embryo plasticity remain largely unknown. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be709680339c0b57100f4348d420fb73
Autor:
Michel Boivin, William Mansfield
Publikováno v:
Southwest Journal of Pulmonary and Critical Care, Vol 14, Iss 2, Pp 60-64 (2017)
No abstract available. Article truncated after first page. A 46-year-old man presented after a motor vehicle collision. He suffered abdominal injuries (liver laceration, avulsed gall bladder) which were successfully managed non-operatively. The patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4213e2d329bd508cb6df4fbf36e0d8ca
https://doi.org/10.13175/swjpcc013-17
https://doi.org/10.13175/swjpcc013-17