Zobrazeno 1 - 10 of 37 pro vyhledávání: '"William M. Spees"'
1
Akademický článek
Detection of early-stage NASH using non-invasive hyperpolarized 13C metabolic imaging
Autor: Cornelius von Morze, Tyler Blazey, Ashley Shaw, William M. Spees, Kooresh I. Shoghi, Michael A. Ohliger
Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Non-alcoholic steatohepatitis (NASH) is characterized from its early stages by a profound remodeling of the liver microenvironment, encompassing changes in the composition and activities of multiple cell types and associated gene expression
Externí odkaz: https://doaj.org/article/bad18c413d474ea58763ceed23b430c2
Zobrazit plný text záznamu
2
Akademický článek
Diffusion fMRI detects white-matter dysfunction in mice with acute optic neuritis
Autor: Tsen-Hsuan Lin, William M. Spees, Chia-Wen Chiang, Kathryn Trinkaus, Anne H. Cross, Sheng-Kwei Song
Publikováno v: Neurobiology of Disease, Vol 67, Iss , Pp 1-8 (2014)
Optic neuritis is a frequent and early symptom of multiple sclerosis (MS). Conventional magnetic resonance (MR) techniques provide means to assess multiple MS-related pathologies, including axonal injury, demyelination, and inflammation. A method to
Externí odkaz: https://doaj.org/article/dc9831a6defd4b68b184772740f27a10
Zobrazit plný text záznamu
7
Data from Imaging Transgene Activity In vivo
Autor: Juri G. Gelovani, Ronald G. Blasberg, Philipp Mayer-Kuckuk, William P. Tong, H. Carl Le, Kristen L. Zakian, Tatiana Beresten, Ian M. Buchanan, Michael Doubrovin, Vladimir Ponomarev, Bradley J. Beattie, William M. Spees, Jason A. Koutcher, Terence P.F. Gade
The successful translation of gene therapy for clinical application will require the assessment of transgene activity as a measure of the biological function of a therapeutic transgene. Although current imaging permits the noninvasive detection of tr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06dc5a0ff6df30871ea7f1c8c0946b15
https://doi.org/10.1158/0008-5472.c.6498144.v1
Zobrazit plný text záznamu
9
Rat Brain Global Ischemia–Induced Diffusion Changes Revisited: Biophysical Modeling of the Water and NAA MR 'Diffusion Signal'
Autor: William M. Spees, Alex L. Sukstanskii, G. Larry Bretthorst, Jeffrey J. Neil, Joseph J.H. Ackerman
Publikováno v: Magnetic Resonance in Medicine. 88:1333-1346
To assess changes in intracellular diffusion as a mechanism for the reduction in water ADC that accompanies brain injury. Using NAA as a marker of neuronal cytoplasmic diffusion, NAA diffusion was measured before and after global ischemia (immediatel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23aefaac8487c051fb7ccd5915bd2216
https://doi.org/10.1002/mrm.29262
Zobrazit plný text záznamu
10
Noninvasive Quantification of Axonal Loss in the Presence of Tissue Swelling in Traumatic Spinal Cord Injury Mice
Autor: Fay C Hwang, Wilson Z. Ray, Peng Sun, Mitchell Hallman, Tsen-Hsuan Lin, Michael Wallendorf, William M. Spees, Sheng-Kwei Song
Publikováno v: J Neurotrauma
Neuroimaging plays an important role in assessing axonal pathology after traumatic spinal cord injury. However, coexisting inflammation confounds imaging assessment of the severity of axonal injury. Herein, we applied diffusion basis spectrum imaging
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::507ea5d40d5e065c6ccf8049f7705223
https://doi.org/10.1089/neu.2018.6016
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje