Zobrazeno 1 - 10
of 12
pro vyhledávání: '"William M. Schopperle"'
Autor:
Claudia Schäfer, Yawen Ju, Youngbin Tak, Cesar Vazquez, Sangyoon J. Han, Edwin Tan, Jerry W. Shay, Mats Holmqvist, Gaudenz Danuser, William M. Schopperle, Glenn Bubley
Publikováno v:
Heliyon, Vol 6, Iss 1, Pp e03263- (2020)
Purpose: Over 90% of all cancer related deaths are due to metastasis. However, current diagnostic tools can't reliably discriminate between invasive and localized cancers. Patients and methods: In this proof-of-concept study, we employed the embryoni
Externí odkaz:
https://doaj.org/article/520573ffb5aa479f9218d8f1e9d2ed89
Autor:
William M. Schopperle, Elisabeth I. Heath, Akhila N. W. Kuda-Wedagedara, Madison N. Wicker, Nerissa T. Viola, Jordan M. White, Daniel E. Spratt
Publikováno v:
Mol Pharm
TRA-1–60 (TRA) is a cell-surface antigen implicated in drug resistance, relapse, and recurrence. Its expression has been reported in breast, prostate, pancreatic, ovarian tumors, and follicular lymphoma, which paved the development of the therapeut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30a8e03c97c1d030d5541f1dce406a65
https://doi.org/10.1021/acs.molpharmaceut.9b01181
https://doi.org/10.1021/acs.molpharmaceut.9b01181
Autor:
Lance K. Heilbrun, Susan Bolton, Daryn Smith, William M. Schopperle, Wael Sakr, Elisabeth I. Heath, Quratulain Ahmed, Yawen Ju
Background/aim Podocalyxin, a member of the CD34 family of cell surface sialomucins, is overexpressed in human embryonal carcinoma cell lines, as well as in several cancer types, and is associated with poor prognosis. Podocalyxin variants are associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5870837579d8fe6f95007a80384537d9
https://europepmc.org/articles/PMC6844084/
https://europepmc.org/articles/PMC6844084/
Publikováno v:
Andrologia. 27:107-113
Testicular tissue from mature male Sprague-Dawley rats was maintained in culture at 33 degrees C or 37 degrees C. Detergent-extracted proteins were separated by polyacrylamide gel electrophoresis (PAGE) followed by staining or fluorography. Unilatera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1aef85bd2873553b41abab7c4406af0
https://doi.org/10.1111/j.1439-0272.1995.tb01079.x
https://doi.org/10.1111/j.1439-0272.1995.tb01079.x
Publikováno v:
Biochemical and biophysical research communications. 398(3)
Podocalyxin, an integral plasma membrane cell-adhesion glycoprotein, is a marker of human pluripotent and multipotent stem cells. Podocalyxin is also a marker of many types of cancers and its expression correlates with an aggressive and poor-prognosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c58e9ca0b377ab26429b5c108c0723e
https://pubmed.ncbi.nlm.nih.gov/20599725
https://pubmed.ncbi.nlm.nih.gov/20599725
Publikováno v:
Fertility and Sterility. 54:902-905
Protein expression by sperm obtained from men with normal semen analysis and men with oligospermia were evaluated by two-dimensional gel electrophoresis. Proteins were solubilized in a 9.5 M urea/2% Nonidet-P40 (LKB, Bromma, Sweden) lysis buffer and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::708e535f700fb284f2b8e99d14f8c4f5
https://doi.org/10.1016/s0015-0282(16)53953-3
https://doi.org/10.1016/s0015-0282(16)53953-3
Publikováno v:
Stem cells (Dayton, Ohio). 25(3)
We have previously identified the cell adhesion protein podocalyxin expressed in a human pluripotent stem cell, embryonal carcinoma (EC), which is a malignant germ cell. Podocalyxin is a heavily glycosylated membrane protein with amino acid sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b39785d343248acb42a060e2930886e0
https://pubmed.ncbi.nlm.nih.gov/17124010
https://pubmed.ncbi.nlm.nih.gov/17124010
Publikováno v:
The FASEB Journal. 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::285f79c776baab84824cf7ba65524cfb
https://doi.org/10.1096/fasebj.20.5.a873
https://doi.org/10.1096/fasebj.20.5.a873
Publikováno v:
Journal of Urology. 154:275-277
We recently purified a 200 kD peanut agglutinin-binding glycoprotein from the embryonal carcinoma cell line HT-E (833K) that is expressed selectively in nonseminomatous germ cell tumors. We now further characterize gp200 using Western blot analysis t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bc27b3b864150ad1d797f2fbc808ea8
https://doi.org/10.1016/s0022-5347(01)67293-8
https://doi.org/10.1016/s0022-5347(01)67293-8
Publikováno v:
Journal of Urology. 171:309-310
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c2305a974ec0ddd2876faed0e09f66b
https://doi.org/10.1016/s0022-5347(18)38412-x
https://doi.org/10.1016/s0022-5347(18)38412-x