Zobrazeno 1 - 10
of 15
pro vyhledávání: '"William M. McShan"'
Autor:
Lerin R. Luckett-Chastain, Catherine J. King, William M. McShan, Jenny R. Gipson, Allison F. Gillaspy, Randle M. Gallucci
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
The skin functions as a protective barrier to inhibit the entry of foreign pathogens, all the while hosting a diverse milieu of microorganisms. Over time, skin cells, immune cells, cytokines, and microbes interact to integrate the processes of mainta
Externí odkaz:
https://doaj.org/article/5f37c4e15c464a8288d015c453f25348
Publikováno v:
Journal of Bacteriology. 200
Lytic bacteriophage A25, which infects Streptococcus pyogenes and several related species, has been used to better understand phage-microbe interactions due to its ability to mediate high-efficiency transduction. Most of these studies, however, are d
Autor:
Jeffrey A. Mayfield, Francis J. Castellino, Victoria A. Ploplis, Zhong Liang, William M. McShan, Yun-Juan Bao, Shaun W. Lee
Symmetric genomic rearrangements around replication axes in genomes are commonly observed in prokaryotic genomes, including Group A Streptococcus (GAS). However, asymmetric rearrangements are rare. Our previous studies showed that the hypervirulent i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ef52ba13df7c2ca450c2ed32c540b47
https://europepmc.org/articles/PMC5903213/
https://europepmc.org/articles/PMC5903213/
Publikováno v:
International Journal of Medical Microbiology. 296:259-275
In this investigation, we identify the CodY protein from Streptococcus pyogenes as a pleiotropic transcription regulator with global features. The notion that acquisition of nutrients by this polyauxotrophic organism is the primary event occurring du
Autor:
Dragana Ajdic, Fares Z. Najar, Joseph J. Ferretti, Matthew B. Carson, Hongshing Lai, Jim White, Hua Zhu, Bruce A. Roe, Shuling Li, Runying Tian, Gorana Savic, William M. McShan, Honggui Jia, Robert E. McLaughlin, Shaoping Lin, Steve Kenton, Yudong Qian, Jin Chang, Charles Primeaux
Publikováno v:
Proceedings of the National Academy of Sciences. 99:14434-14439
Streptococcus mutans is the leading cause of dental caries (tooth decay) worldwide and is considered to be the most cariogenic of all of the oral streptococci. The genome of S. mutans UA159, a serotype c strain, has been completely sequenced and is c
Autor:
William M. McShan, Scott V. Nguyen
Publikováno v:
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology, Vol 4 (2014)
Frontiers in Cellular and Infection Microbiology, Vol 4 (2014)
Streptococcus pyogenes is a significant pathogen of humans, annually causing over 700,000,000 infections and 500,000 deaths. Virulence in S. pyogenes is closely linked to mobile genetic elements like phages and chromosomal islands (CI). S. pyogenes p
Publikováno v:
The FASEB Journal. 28
Nearly 5 million barrels of oil were released into the Gulf of Mexico following the Deepwater Horizon oil well failure, making it undoubtedly the largest environmental disaster response effort in U.S. history. Spill remediation workers were continuou
Publikováno v:
FEMS Microbiology Letters. 191:235-241
The gene for NAD-glycohydrolase (nga) of group A streptococci (Streptococcus pyogenes) was identified and shown to be located immediately adjacent to the gene for streptolysin O (slo). The nga gene contains 1341 base pairs and encodes a protein of 44
Publikováno v:
Frontiers in Microbiology, Vol 3 (2012)
Frontiers in Microbiology
Frontiers in Microbiology
We recently showed that a prophage-like Streptococcus pyogenes chromosomal island (SpyCI) controls DNA mismatch repair (MMR) and other repair functions in M1 genome strain SF370 by dynamic excision and reintegration into the 5’ end of mutL in respo
Autor:
Dragutin J. Savic, William M. McShan
Publikováno v:
Microbiology (Reading, England). 158(Pt 6)
The mechanisms that allow Streptococcus pyogenes to survive and persist in the human host, often in spite of antibiotic therapy, remain poorly characterized. Therefore, the determination of culture conditions for long-term studies is crucial to advan