Zobrazeno 1 - 10
of 63
pro vyhledávání: '"William M. McIsaac"'
Autor:
Haakon Ragde, Lawrence J. McCormack, Donald B. Effler, William M. McIsaac, Laurence K. Groves
Publikováno v:
Cleveland Clinic Journal of Medicine. 28:145-156
Publikováno v:
Canadian Journal of Chemistry. 45:2963-2967
Some aromatic 1-aryl(and 1-aralkyl)-β-carbolines were prepared from their tetrahydro analogues by dehydrogenation over palladium on charcoal either in a Parr bomb or in refluxing toluene. The bomb reaction appears to be a better procedure for the pr
Autor:
William M. McIsaac
Publikováno v:
Cleveland Clinic Journal of Medicine. 29:76-80
Publikováno v:
Journal of Chromatography A. 31:446-454
Chromatography of a series of seventy-three β-carbolines was carried out on both paper and thin-layer plates in acidic, basic, and neutral solvents. The best solvent for the separation is the neutral and polar solvent such as chloroform-methanol on
Autor:
William M. McIsaac, Robert G. Taborsky
Publikováno v:
Journal of Medicinal Chemistry. 7:135-141
Autor:
Juhana J. Idänpään-Heikkilä, William M. McIsaac, G. Edward Fritchie, Beng T. Ho, Vicente Estevez, L. Wayne Tansey
Publikováno v:
Biochemical Pharmacology. 20:1313-1319
The distribution and metabolic fate of [3H]harmaline-HCl were studied in rats. Thirty min after subcutaneous injection, high radioactivity was found in the small intestine, liver, adrenals, kidneys and lungs. A rapid turnover and elimination was evid
Publikováno v:
Life Sciences. 11:493-502
6-Methoxy-1,2,3,4-tetrahydro-β-carboline (6-MeO-THBC), which exerts its effect specifically on brain serotonin (5-HT), caused substantial increase of the amine in all the discrete areas of the rat brain. Since norepinephrine levels were unchanged, t
Autor:
William M. McIsaac, Sergije Kveder
Publikováno v:
Journal of Biological Chemistry. 236:3214-3220
Publikováno v:
Annals of the New York Academy of Sciences. 215:346-355
Publikováno v:
Journal of Medicinal Chemistry. 12:45-48