Zobrazeno 1 - 10
of 29
pro vyhledávání: '"William M. Kulyk"'
Autor:
Dennis O. Okello, Paul P. R. Iyyanar, William M. Kulyk, Tara M. Smith, Scott Lozanoff, Shaoping Ji, Adil J. Nazarali
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Cleft palate is a common congenital abnormality that results from defective secondary palate (SP) formation. The Sine oculis-related homeobox 2 (Six2) gene has been linked to abnormalities of craniofacial and kidney development. Our current study exa
Externí odkaz:
https://doaj.org/article/ebcb3005b86949b2aa14106f185aaa79
Publikováno v:
Journal of Functional Biomaterials, Vol 5, Iss 3, Pp 197-210 (2014)
Osteoarthritis is a painful degenerative joint disease that could be better managed if tissue engineers can develop methods to create long-term engineered articular cartilage tissue substitutes. Many of the tissue engineered cartilage constructs curr
Externí odkaz:
https://doaj.org/article/1587874f817b4df1bf62bedab7ab210a
Publikováno v:
Tissue Engineering Part C: Methods. 22:173-188
Three-dimensional (3D) bioprinting of hybrid constructs is a promising biofabrication method for cartilage tissue engineering because a synthetic polymer framework and cell-impregnated hydrogel provide structural and biological features of cartilage,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75b7ec8921a4580b4236c76d07fc1f13
https://doi.org/10.1089/ten.tec.2015.0307
https://doi.org/10.1089/ten.tec.2015.0307
Publikováno v:
Journal of Functional Biomaterials; Volume 5; Issue 3; Pages: 197-210
Journal of Functional Biomaterials
Journal of Functional Biomaterials, Vol 5, Iss 3, Pp 197-210 (2014)
Journal of Functional Biomaterials
Journal of Functional Biomaterials, Vol 5, Iss 3, Pp 197-210 (2014)
Osteoarthritis is a painful degenerative joint disease that could be better managed if tissue engineers can develop methods to create long-term engineered articular cartilage tissue substitutes. Many of the tissue engineered cartilage constructs curr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc79db39d7dff9a814d7a9ea0e74c409
https://doi.org/10.3390/jfb5030197
https://doi.org/10.3390/jfb5030197
Publikováno v:
Journal of Functional Biomaterials, Vol 3, Iss 4, Pp 799-838 (2012)
Journal of Functional Biomaterials
Journal of Functional Biomaterials
Damage to articular cartilage can eventually lead to osteoarthritis (OA), a debilitating, degenerative joint disease that affects millions of people around the world. The limited natural healing ability of cartilage and the limitations of currently a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bafd65bf3f3ca3dcc97f07f0cc6dade4
http://www.mdpi.com/2079-4983/3/4/799
http://www.mdpi.com/2079-4983/3/4/799
Publikováno v:
Journal of Cellular Biochemistry. 112:3440-3448
One of the earliest events during chondrogenesis is the formation of condensations, a necessary pre-requisite for subsequent differentiation of a chondrogenic phenotype. Members of the Fibronectin Lecucine Rich Transmembrane (FLRT) proteins have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc6948dd3069b0cb692bec3ca1a436a7
https://doi.org/10.1002/jcb.23271
https://doi.org/10.1002/jcb.23271
Publikováno v:
Journal of Cellular Physiology. 211:233-243
Fibroblast growth factors (FGFs) and their receptors play fundamental roles regulating growth, morphogenesis, and cartilage formation in embryonic limbs and facial primordia. However, the intracellular pathways that transduce FGF signals during the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5eace629fb430ce446689aaa1475f51
https://doi.org/10.1002/jcp.20923
https://doi.org/10.1002/jcp.20923
Autor:
Brent E. Bobick, William M. Kulyk
Publikováno v:
Experimental Cell Research. 312:1079-1092
The extracellular signal-regulated kinase (ERK) mitogen-activated protein kinase pathway, also known as the MEK-ERK cascade, has been shown to regulate cartilage differentiation in embryonic limb mesoderm and several chondrogenic cell lines. In the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1086358558bdfb96ab27a8a8042df4c
https://doi.org/10.1016/j.yexcr.2005.12.028
https://doi.org/10.1016/j.yexcr.2005.12.028
Autor:
Robert J. Winkfein, Jian Fei Wang, J. Barry Wright, David A. Hart, William M. Kulyk, Merle E. Olson
Publikováno v:
Wound Repair and Regeneration. 10:230-240
Heat shock protein (HSP) 47 is a major stress-inducible protein that is localized to the endoplasmic reticulum of avian and mammalian cells and is thought to act as a molecular chaperone specific for the processing of procollagen. However, limited in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d909d380004a419b37162f0f5d7cc51
https://doi.org/10.1046/j.1524-475x.2002.10406.x
https://doi.org/10.1046/j.1524-475x.2002.10406.x
Publikováno v:
Experimental Cell Research. 255:327-332
Sox9 plays a crucial role in chondrogenesis. It encodes an HMG-domain transcription factor that activates an enhancer in the gene for type II collagen (Col2a1), a principal cartilage matrix protein. We have characterized the temporal pattern of Sox9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ebdb3f7f3bbf5a7ecfc82f501236993
https://doi.org/10.1006/excr.1999.4784
https://doi.org/10.1006/excr.1999.4784