Zobrazeno 1 - 10
of 39
pro vyhledávání: '"William M. Keyes"'
Autor:
Andrea Riba, Attila Oravecz, Matej Durik, Sara Jiménez, Violaine Alunni, Marie Cerciat, Matthieu Jung, Céline Keime, William M. Keyes, Nacho Molina
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Single-cell RNA-sequencing technology gives access to cell cycle dynamics without externally perturbing the cell. Here the authors present DeepCycle,a robust deep learning method to infer the cell cycle state in single cells from scRNA-seq data.
Externí odkaz:
https://doaj.org/article/341a0ba6bc3645fd9825106ec997e38b
Autor:
Muriel Rhinn, Irene Zapata-Bodalo, Annabelle Klein, Jean-Luc Plassat, Tania Knauer-Meyer, William M. Keyes
Publikováno v:
PLoS Biology, Vol 20, Iss 6 (2022)
Valproic acid (VPA) is a widely prescribed drug to treat epilepsy, bipolar disorder, and migraine. If taken during pregnancy, however, exposure to the developing embryo can cause birth defects, cognitive impairment, and autism spectrum disorder. How
Externí odkaz:
https://doaj.org/article/196cb88e19c74ee3906a1ca9a37e2ea9
Publikováno v:
The FEBS Journal. 290:1303-1313
Autor:
Matej Durik, Daniel Sampaio Gonçalves, Coralie Spiegelhalter, Nadia Messaddeq, William M. Keyes
Cellular senescence is a complex cell state with roles in tumor suppression, embryonic development and wound repair. However, when misregulated, senescence contributes to aging and disease. Here we identify that senescent cells generate/break off lar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fbc33e64d52236c188c33c3fe834ef5
https://doi.org/10.1101/2023.01.11.523642
https://doi.org/10.1101/2023.01.11.523642
Autor:
Matej Durik, William M. Keyes
Publikováno v:
Nature Aging. 2:570-572
Publikováno v:
Genesdevelopment. 36(9-10)
Senescence is a specialized form of cell cycle arrest induced in response to damage and stress. In certain settings, senescent cells can promote their own removal by recruitment of the immune system, a process that is thought to decline in efficiency
Autor:
Muriel Rhinn, Irene Zapata-Bodalo, Annabelle Klein, Jean-Luc Plassat, Tania Knauer-Meyer, William M. Keyes
Publikováno v:
Plos Biology
Plos Biology, 2022, 20 (6), pp.e3001664. ⟨10.1371/journal.pbio.3001664⟩
PLoS Biology
PLoS Biology, 2022, 20 (6), ⟨10.1371/journal.pbio.3001664⟩
Plos Biology, 2022, 20 (6), pp.e3001664. ⟨10.1371/journal.pbio.3001664⟩
PLoS Biology
PLoS Biology, 2022, 20 (6), ⟨10.1371/journal.pbio.3001664⟩
International audience; Abstract Valproic acid (VPA) is widely prescribed to treat epilepsy, bipolar disorder and migraine. However, if taken during pregnancy, exposure to the developing embryo can cause birth defects, cognitive impairment and Autism
Autor:
Tania Knauer-Meyer, Irene Zapata-Bodalo, Annabelle Klein, William M. Keyes, Jean-Luc Plassat, Muriel Rhinn
Timely induction of cellular senescence is important during embryonic development and tissue repair, while aberrant activation contributes to many age-related diseases. However, whether abnormal induction of senescence in the embryo contributes to de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1b8c0967e33e230a33ef7df889c4fd3
https://doi.org/10.1101/2021.05.28.446099
https://doi.org/10.1101/2021.05.28.446099
Autor:
Andrea Riba, Attila Oravecz, Matej Durik, Sara Jiménez, Violaine Alunni, Marie Cerciat, Matthieu Jung, Céline Keime, William M. Keyes, Nacho Molina
Publikováno v:
Nature Communications
Nature Communications, 2022, 13 (1), pp.2865. ⟨10.1038/s41467-022-30545-8⟩
Nature Communications, 2022, 13 (1), pp.2865. ⟨10.1038/s41467-022-30545-8⟩
Despite the fact that the cell cycle is a fundamental process of life, a detailed quantitative understanding of gene regulation dynamics throughout the cell cycle is far from complete. Single-cell RNA-sequencing (scRNA-seq) technology gives access to
Autor:
Cerciat M, William M. Keyes, Durik M, Céline Keime, Oravecz A, Sara Jiménez, Jung M, Alunni, Nacho Molina, Andrea Riba
The cell cycle is a fundamental process of life, however, a quantitative understanding of gene regulation dynamics in the context of the cell cycle is still far from complete. Single-cell RNA-sequencing (scRNA-seq) technology gives access to its dyna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::277c643c826da714dc482f7ff24b8a0d
https://doi.org/10.1101/2021.03.17.435887
https://doi.org/10.1101/2021.03.17.435887