Zobrazeno 1 - 10
of 58
pro vyhledávání: '"William M. Flanagan"'
Autor:
Jean H. E. Yong, Claude Nadeau, William M. Flanagan, Andrew J. Coldman, Keiko Asakawa, Rochelle Garner, Natalie Fitzgerald, Martin J. Yaffe, Anthony B. Miller
Publikováno v:
Current Oncology, Vol 29, Iss 3, Pp 1619-1633 (2022)
Background: OncoSim-Breast is a Canadian breast cancer simulation model to evaluate breast cancer interventions. This paper aims to describe the OncoSim-Breast model and how well it reproduces observed breast cancer trends. Methods: The OncoSim-Breas
Externí odkaz:
https://doaj.org/article/999932c21b3e40cfb2a51e03f931a1a8
Autor:
Shanu Modi, Geoffrey I. Shapiro, Alexander Ungewickell, S. Renee Commerford, William M. Flanagan, Jennifer M. Giltnane, Walter C. Darbonne, Montserrat Carrasco-Triguero, Flavia Brunstein, Eva Schuth, Denise Nazzal, Shang-Chiung Chen, Ching-Wei Chang, Sarat Chandarlapaty, Colin D. Weekes, Patricia M. LoRusso, Joseph P. Eder, Khanh T. Do, Sara M. Tolaney
Purpose:DLYE5953A is an antibody–drug conjugate consisting of an anti-LY6E antibody covalently linked to the cytotoxic agent monomethyl auristatin E. This study characterized the safety, pharmacokinetics, immunogenicity, potential biomarkers, and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1814cc1e18987b8c0209348c7dc45f90
https://doi.org/10.1158/1078-0432.c.6529674
https://doi.org/10.1158/1078-0432.c.6529674
Autor:
Shanu Modi, Geoffrey I. Shapiro, Alexander Ungewickell, S. Renee Commerford, William M. Flanagan, Jennifer M. Giltnane, Walter C. Darbonne, Montserrat Carrasco-Triguero, Flavia Brunstein, Eva Schuth, Denise Nazzal, Shang-Chiung Chen, Ching-Wei Chang, Sarat Chandarlapaty, Colin D. Weekes, Patricia M. LoRusso, Joseph P. Eder, Khanh T. Do, Sara M. Tolaney
Tables S1 to S9 Figures S1 to S6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65ad8d45ab0db7651fe443490a72901f
https://doi.org/10.1158/1078-0432.22477479
https://doi.org/10.1158/1078-0432.22477479
Publikováno v:
Scandinavian Journal of Work, Environment & Health, Vol 41, Iss 4, Pp 407-412 (2015)
OBJECTIVES: The study aimed to incorporate an estimate of risk for asbestos exposure in the Canadian Cancer Risk Management Lung Cancer (CRMM-LC) microsimulation model. METHODS: In CRMM-LC, a 3-year probability of developing lung cancer can be derive
Externí odkaz:
https://doaj.org/article/c38aeaa277be4530afdab3303bb80e8c
Autor:
William K. Evans, William M Flanagan, Michael Wolfson, John R Goffin, C. Gauvreau, Anthony B Miller, S. Memon, N. Fitzgerald, Jean Hai Ein Yong
Publikováno v:
CMAJ Open
Background Low-dose computed tomography (CT) screening can reduce lung cancer mortality in people at high risk; adding a smoking cessation intervention to screening could further improve screening program outcomes. This study aimed to assess the impa
Autor:
N. Fitzgerald, Anthony B. Miller, Claude Nadeau, Rochelle Garner, A. Coldman, Keiko Asakawa, Yaffe M, William M. Flanagan, Jean Hai Ein Yong
Publikováno v:
Current Oncology; Volume 29; Issue 3; Pages: 1619-1633
BackgroundThe increasing demand for health care resources requires measures to evaluate the impact of cancer control approaches. A cancer simulation model can help integrate new knowledge to inform clinical and policy decisions. OncoSim-Breast is a b
Autor:
Joy Pader, Claude Nadeau, Craig C. Earle, Jason Lacombe, Cynthia Gauvreau, Andrew J. Coldman, William M. Flanagan, Michael Wolfson, S. Memon, Anthony B. Miller, N. Fitzgerald
Publikováno v:
Journal of Cancer Policy. 15:52-58
Introduction Projection of the effect of cancer screening interventions are frequently conducted using complex simulation models. It is important that such models demonstrate their ability to replicate observational results on the effect of screening
Autor:
Claude Nadeau, Andrew J. Coldman, William K. Evans, C. Gauvreau, Michael Wolfson, N. Fitzgerald, Keiko Asakawa, William M. Flanagan, Cathy Popadiuk, Anthony B. Miller, Rochelle Garner, S. Memon
Publikováno v:
Current Oncology
Volume 24
Issue 6
Pages 3850-406
Volume 24
Issue 6
Pages 3850-406
The Canadian Partnership Against Cancer was created in 2007 by the federal government to accelerate cancer control across Canada. Its OncoSim microsimulation model platform, which consists of a suite of specific cancer models, was conceived as a tool
Autor:
Andrew J. Coldman, C. Gauvreau, N. Fitzgerald, S. Memon, Craig C. Earle, Claude Nadeau, Michael Wolfson, Anthony B. Miller, William M. Flanagan
Publikováno v:
Journal of Cancer Policy. 13:38-46
Background Immunochemical faecal testing (FIT) is used in Canada for colorectal cancer (CRC) screening. The threshold for FIT abnormality is under operator control and this study uses a simulation model to predict the effect of threshold selection on
Autor:
Shahzad Ghanbarian, Amin Adibi, Kate M Johnson, Mohsen Sadatsafavi, William M. Flanagan, Stirling Bryan, J Mark FitzGerald, Don D. Sin
Publikováno v:
Medical decision making : an international journal of the Society for Medical Decision Making. 39(2)
We report the development, validation, and implementation of an open-source population-based outcomes model of chronic obstructive pulmonary disease (COPD) for Canada.Evaluation Platform in COPD (EPIC) is a discrete-event simulation model of Canadian