Zobrazeno 1 - 10
of 51
pro vyhledávání: '"William M. F. Lee"'
Autor:
Raghav K Padmanabhan, Vinay H Somasundar, Sandra D Griffith, Jianliang Zhu, Drew Samoyedny, Kay See Tan, Jiahao Hu, Xuejun Liao, Lawrence Carin, Sam S Yoon, Keith T Flaherty, Robert S Dipaola, Daniel F Heitjan, Priti Lal, Michael D Feldman, Badrinath Roysam, William M F Lee
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90495 (2014)
Currently, no available pathological or molecular measures of tumor angiogenesis predict response to antiangiogenic therapies used in clinical practice. Recognizing that tumor endothelial cells (EC) and EC activation and survival signaling are the di
Externí odkaz:
https://doaj.org/article/b8e0757015ca4903a861212a86e9581e
Autor:
George J Cerniglia, Nabendu Pore, Jeff H Tsai, Susan Schultz, Rosemarie Mick, Regine Choe, Xiaoman Xing, Turgut Durduran, Arjun G Yodh, Sydney M Evans, Cameron J Koch, Stephen M Hahn, Harry Quon, Chandra M Sehgal, William M F Lee, Amit Maity
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6539 (2009)
Epidermal growth factor receptor (EGFR) inhibitors have shown only modest clinical activity when used as single agents to treat cancers. They decrease tumor cell expression of hypoxia-inducible factor 1-alpha (HIF-1alpha) and vascular endothelial gro
Externí odkaz:
https://doaj.org/article/a6b2d0eb973c42e2be7da916ee22a4ed
Autor:
Kedar Grama, Michael Feldman, Badrinath Roysam, Wiem Lassoued, William M. F. Lee, Sumit K Nath, Yousef Al-Kofahi, Jianliang Zhu, Ridha Oueslati
Publikováno v:
Histopathology. 59:40-54
Aims To investigate the use of a computer-assisted technology for objective, cell-based quantification of molecular biomarkers in specified cell types in histopathology specimens, with the aim of advancing current visual estimation or pixel-level (ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::152651701a119d0bbe9b9a4807a59bdd
https://doi.org/10.1111/j.1365-2559.2011.03878.x
https://doi.org/10.1111/j.1365-2559.2011.03878.x
Publikováno v:
Ultrasound in Medicine & Biology. 36:853-857
The goal of this murine investigation was to evaluate the effect of an antivascular ultrasound treatment on the growth of an implanted melanoma and the consequent survival rate. After the intravenous injection of 0.2 mL ultrasound contrast agent (Def
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::025b61bcc6267f845a88e5f86ad1112c
https://doi.org/10.1016/j.ultrasmedbio.2010.02.001
https://doi.org/10.1016/j.ultrasmedbio.2010.02.001
Autor:
Heather E. Price, Jeff H. Tsai, Ralph M. Bunte, Margaret S. Deitz, William M. F. Lee, Andrew K.W. Wood, Chandra M. Sehgal
Publikováno v:
Academic Radiology. 15:1133-1141
Rationale and Objectives The goal was to determine whether the tumor vascular disrupting actions of low-intensity ultrasound were frequency dependent. Materials and Methods The effect of the frequency (1 MHz at 2.2 W/cm 2 or 3 MHz at 2.4 W/cm 2 ) of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af8570c6447413992d27046c82e5bd21
https://doi.org/10.1016/j.acra.2008.04.012
https://doi.org/10.1016/j.acra.2008.04.012
Autor:
William M. F. Lee, Chandra M. Sehgal, Ralph M. Bunte, Andrew K.W. Wood, Jennie D. Cohen, Jeff H. Tsai
Publikováno v:
Ultrasound in Medicine & Biology. 33:1901-1910
This study investigated whether a microbubble-containing ultrasound contrast agent had a role in the antivascular action of physiotherapy ultrasound on tumor neovasculature. Ultrasound images (B-mode and contrast-enhanced power Doppler (0.02 mL Defin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ba7b7cbc72047c2e27238ae27d8a6a
https://doi.org/10.1016/j.ultrasmedbio.2007.06.013
https://doi.org/10.1016/j.ultrasmedbio.2007.06.013
Autor:
Duonan Yu, Greg H. Enders, Joshua T. Mendell, Danielle Murphy, William M. F. Lee, Andrei Thomas-Tikhonenko, Erik A. Wentzel, Michael Dews, Asal Homayouni, Emma E. Furth, Cinzia Sevignani
Publikováno v:
Nature Genetics. 38:1060-1065
Human adenocarcinomas commonly harbor mutations in the KRAS and MYC proto-oncogenes and the TP53 tumor suppressor gene. All three genetic lesions are potentially pro-angiogenic, as they sustain production of vascular endothelial growth factor (VEGF).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d131ba7d77f6a085696284f8f6623ce
https://doi.org/10.1038/ng1855
https://doi.org/10.1038/ng1855
Autor:
Danielle Murphy, George P. Liao, Timothy J. Gardner, H. Lee Sweeney, Corinna M. Panlilio, William M. F. Lee, Y. Joseph Woo, Kevin J. Morine, Mark F. Berry, Jeffrey E. Cohen, Vivian M. Hsu, Matthew J. Leskowitz, Pavan Atluri, Erik E. Suarez
Publikováno v:
The Annals of Thoracic Surgery. 81:1728-1736
Background Ischemic cardiomyopathy is a global health concern with limited therapy. We recently described endogenous revascularization utilizing granulocyte-macrophage colony stimulating factor (GMCSF) to induce endothelial progenitor cell (EPC) prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71ab5e3190e18124890dfcbcdebe5254
https://doi.org/10.1016/j.athoracsur.2005.12.015
https://doi.org/10.1016/j.athoracsur.2005.12.015
Publikováno v:
Ultrasound in Medicine & Biology. 32:453-461
This study evaluates the histopathological changes that follow insonation of a neoplasm with physiotherapy ultrasound. In 27 mice (C3HV/HeN strain), a subcutaneous melanoma (K1735(22)) was insonated with continuous physiotherapy ultrasound (1 MHz; sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9361680c5faef72f7a56ebd2a5dfedee
https://doi.org/10.1016/j.ultrasmedbio.2005.12.005
https://doi.org/10.1016/j.ultrasmedbio.2005.12.005
Autor:
Vinay H. Somasundar, Drew Samoyedny, Sam S. Yoon, Lawrence Carin, Michael Feldman, Keith T. Flaherty, Kay See Tan, Daniel F. Heitjan, Priti Lal, William M. F. Lee, Jiahao Hu, Badrinath Roysam, Xuejun Liao, Jianliang Zhu, Sandra D. Griffith, Raghav Padmanabhan, Robert S. DiPaola
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 3, p e90495 (2014)
PLoS ONE, Vol 9, Iss 3, p e90495 (2014)
Currently, no available pathological or molecular measures of tumor angiogenesis predict response to antiangiogenic therapies used in clinical practice. Recognizing that tumor endothelial cells (EC) and EC activation and survival signaling are the di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d07043f4a864c9276dece0e12da075e
http://europepmc.org/articles/PMC3946171
http://europepmc.org/articles/PMC3946171