Zobrazeno 1 - 10
of 79
pro vyhledávání: '"William M. Clemons"'
Autor:
Katsuhiko Mitachi, Shou M. Kurosu, Cody D. Gillman, Hyun Gi Yun, William M. Clemons, Jr., Michio Kurosu
Publikováno v:
MethodsX, Vol 6, Iss , Pp 2305-2321 (2019)
Immunotherapy that targets N-linked glycans has not yet been developed due in large part to the lack of specificity of N-linked glycans between normal and malignant cells. N-Glycan chains are synthesized by the sequential action of glycosyl transfera
Externí odkaz:
https://doaj.org/article/95996a3fb5d54e9590df403a305b6ff0
Autor:
Katsuhiko Mitachi, Hyun Gi Yun, Sara M. Kurosu, Shakiba Eslamimehr, Maddie R. Lemieux, Lada Klaić, William M. Clemons, Michio Kurosu
Publikováno v:
ACS Omega, Vol 3, Iss 2, Pp 1726-1739 (2018)
Externí odkaz:
https://doaj.org/article/7f888f0e3c984d9c8fc374c766595958
Autor:
Stephen S. Marshall, Michiel J.M. Niesen, Axel Müller, Katrin Tiemann, Shyam M. Saladi, Rachel P. Galimidi, Bin Zhang, William M. Clemons Jr., Thomas F. Miller III
Publikováno v:
Cell Reports, Vol 16, Iss 8, Pp 2169-2177 (2016)
Integral membrane proteins (IMPs) control the flow of information and nutrients across cell membranes, yet IMP mechanistic studies are hindered by difficulties in expression. We investigate this issue by addressing the connection between IMP sequence
Externí odkaz:
https://doaj.org/article/788a5fea2c7941fb9e77e5df89096254
Publikováno v:
Cell Reports, Vol 2, Iss 6, Pp 1620-1632 (2012)
In the cytoplasm, the correct delivery of membrane proteins is an essential and highly regulated process. The posttranslational targeting of the important tail-anchor membrane (TA) proteins has recently been under intense investigation. A specialized
Externí odkaz:
https://doaj.org/article/59a102493aa546a29313c072511e34f4
Publikováno v:
Biophysical Journal. 122:E1-E3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c440410e8d39a3e307b583a238547335
https://doi.org/10.1016/j.bpj.2023.03.025
https://doi.org/10.1016/j.bpj.2023.03.025
Autor:
Michelle Y. Fry, Vladimíra Najdrová, Ailiena O. Maggiolo, Shyam M. Saladi, Pavel Doležal, William M. Clemons
Publikováno v:
Nature Structural & Molecular Biology. 29:820-830
Tail-anchored (TA) membrane proteins, accounting for roughly 2% of proteomes, are primarily targeted posttranslationally to the endoplasmic reticulum membrane by the guided entry of TA proteins (GET) pathway. For this complicated process, it remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7dc91ca7bddf98f8007301da1075d75
https://doi.org/10.1038/s41594-022-00798-4
https://doi.org/10.1038/s41594-022-00798-4
Autor:
Alexandra N. Barlow, M.S. Manu, Shyam M. Saladi, Paul T. Tarr, Yashpal Yadav, Aye M.M. Thinn, Yun Zhu, Arthur D. Laganowsky, William M. Clemons, Sureshkumar Ramasamy
Publikováno v:
Journal of Biological Chemistry. :104752
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dff2d960f216e510d9db064bf5d2e70e
https://doi.org/10.1016/j.jbc.2023.104752
https://doi.org/10.1016/j.jbc.2023.104752
Autor:
Katsuhiko Mitachi, David Mingle, Wendy Effah, Antonio Sánchez‐Ruiz, Kirk E. Hevener, Ramesh Narayanan, William M. Clemons, Francisco Sarabia, Michio Kurosu
Publikováno v:
Angewandte Chemie (International ed. in English). 61(31)
A short total synthesis of tunicamycin V (1), a non-selective phosphotransferase inhibitor, is achieved via a Büchner–Curtius–Schlotterbeck type reaction. Tunicamycin V can be synthesized in 15 chemical steps from D-galactal with 21 % overall yi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c425a9fb61d5fac4afb138e48f990c90
https://pubmed.ncbi.nlm.nih.gov/35594368
https://pubmed.ncbi.nlm.nih.gov/35594368
Publikováno v:
Biophysical Journal. 122:52a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9c963379ae9d8a328fa79ff3499325f
https://doi.org/10.1016/j.bpj.2022.11.489
https://doi.org/10.1016/j.bpj.2022.11.489
Autor:
Michelle Y, Fry, Vladimíra, Najdrová, Ailiena O, Maggiolo, Shyam M, Saladi, Pavel, Doležal, William M, Clemons
Publikováno v:
Nature structuralmolecular biology. 29(8)
Tail-anchored (TA) membrane proteins, accounting for roughly 2% of proteomes, are primarily targeted posttranslationally to the endoplasmic reticulum membrane by the guided entry of TA proteins (GET) pathway. For this complicated process, it remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::52f8d58e5a23372136e10d95e08ed560
https://pubmed.ncbi.nlm.nih.gov/35851188
https://pubmed.ncbi.nlm.nih.gov/35851188