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pro vyhledávání: '"William M Thurlbeck"'
Autor:
William M Thurlbeck
Publikováno v:
Canadian Respiratory Journal, Vol 1, Iss 1, Pp 21-39 (1994)
The present definition or emphysema has three components: enlargement of airspaces. destruction or their walls and lack of fibrosis. Enlargement can be recognized by measuring the intcralvcolar wall distance or by comparing the airspaces under cnnsiJ
Externí odkaz:
https://doaj.org/article/3affbfde4ac34a0085a9f6db96e4b103
Autor:
William M Thurlbeck
Publikováno v:
Canadian Respiratory Journal, Vol 1, Iss 1, Pp 17-18 (1994)
Externí odkaz:
https://doaj.org/article/367408ec5be04149a398c513585af2ce
Autor:
Martin L. Puterman, Harmanjatinder S. Sekhon, Janet E. Larson, Kamala Cherukupalli, William M. Thurlbeck
Publikováno v:
Pediatric Pulmonology. 24:12-21
We compared the ontogeny of collagen (hydroxyproline), elastin (desmosine), soluble protein, and DNA in the lungs of rats and humans during gestation and postnatal life. In humans, lung weight/body weight ratios declined faster during gestation than
Autor:
William M. Thurlbeck, Emad A. S. Massoud, Avi Rotschild, Harmanjatinder S. Sekhon, Alfonso Solimano
Publikováno v:
Pediatric Pulmonology. 23:76-86
Triamcinolone acetonide (TAC) has a potent teratogenic effect on various mammalian fetal tissues as well as a steroid effect on the lung. Less well documented is the fact that it produces profound oligohydramnios. We wished to determine what effect T
Publikováno v:
Respiration Physiology. 106:99-107
Lung morphometry was studied in rats between 4 and 7 weeks of age. The animals were divided into 5 groups: general controls (fed ad libitum), hypobaric normoxic, normobaric hypoxic, hypobaric hypoxic, and weight-matched controls (weight matched to th
Publikováno v:
Respiration Physiology. 105:241-252
Four-week-old rats were divided into five groups: general controls, weight-matched controls (weight matched to hypobaric hypoxia), hypobaric hypoxia, normobaric hypoxia, and hypobaric normoxia. Lung growth impairment in weight-matched animals occurre
Autor:
William M. Thurlbeck, Martin L. Puterman, Emad A. S. Massoud, Alfonso Solimano, Avi Rotschild, Harmanjatinder S. Sekhon
Publikováno v:
Pediatric Pulmonology. 21:219-226
We studied the left lung using multi-focus microphotography in 378 rat fetuses, assessing airway branching from day 13 to day 19 of gestation, and lung growth variables from day 13 to day 21. Longitudinal growth, and monopodial and dichotomous branch
Autor:
William M. Thurlbeck, Ken Saito
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 151:1373-1376
This study clarifies interlobar differences in the severity of emphysema and examines the feasibility of assessing emphysema in a whole lung using either the upper or lower lobes. Midsagittal, paper-mounted whole-lung sections from 79 consecutive aut
Publikováno v:
Pediatric Pulmonology. 18:53-57
Two major factors can interfere with normal development of the fetal lungs: mechanical constriction resulting in decreased intrathoracic space and reduced or absent fetal breathing movements. We report a unique case in which both factors contribute t
Publikováno v:
Experimental Lung Research. 20:27-40
It is yet unknown whether the impaired nutritional status of streptozotocin-induced diabetic rats influences changes in levels of insulin-like growth factor-I (IGF-I) in this experimental model of diabetes. To explore this possibility, simultaneous s