Zobrazeno 1 - 10
of 46
pro vyhledávání: '"William M Schneider"'
Autor:
Melody M H Li, Zerlina Lau, Pamela Cheung, Eduardo G Aguilar, William M Schneider, Leonia Bozzacco, Henrik Molina, Eugen Buehler, Akinori Takaoka, Charles M Rice, Dan P Felsenfeld, Margaret R MacDonald
Publikováno v:
PLoS Pathogens, Vol 13, Iss 1, p e1006145 (2017)
The host factor and interferon (IFN)-stimulated gene (ISG) product, zinc-finger antiviral protein (ZAP), inhibits a number of diverse viruses by usurping and intersecting with multiple cellular pathways. To elucidate its antiviral mechanism, we perfo
Externí odkaz:
https://doaj.org/article/a8efea74f386440099de31c0b39f4517
Autor:
Margaret A Scull, William M Schneider, Brenna R Flatley, Robert Hayden, Canny Fung, Christopher T Jones, Marieke van de Belt, François Penin, Charles M Rice
Publikováno v:
PLoS Pathogens, Vol 11, Iss 11, p e1005297 (2015)
The hepatitis C virus (HCV) p7 protein is required for infectious virus production via its role in assembly and ion channel activity. Although NMR structures of p7 have been reported, the location of secondary structural elements and orientation of t
Externí odkaz:
https://doaj.org/article/8e98e42c107d473fa2317db2b1406289
Autor:
Yingpu Yu, William M. Schneider, Maximilian A. Kass, Eleftherios Michailidis, Ashley Acevedo, Ana L. Pamplona Mosimann, Juliano Bordignon, Alexander Koenig, Christine M. Livingston, Hardeep van Gijzel, Yi Ni, Pradeep M. Ambrose, Catherine A. Freije, Mengyin Zhang, Chenhui Zou, Mohammad Kabbani, Corrine Quirk, Cyprien Jahan, Xianfang Wu, Stephan Urban, Shihyun You, Amir Shlomai, Ype P. de Jong, Charles M. Rice
Publikováno v:
Science Advances. 9
Hepatitis B virus (HBV) chronically infects an estimated 300 million people, and standard treatments are rarely curative. Infection increases the risk of liver cirrhosis and hepatocellular carcinoma, and consequently, nearly 1 million people die each
Publikováno v:
Current Opinion in Virology
Flaviviruses are zoonotic pathogens transmitted by the bite of infected mosquitos and ticks and represent a constant burden to human health. Here we review recent literature aimed at uncovering how flaviviruses interact with the cells that they infec
Autor:
Mohammad Sadic, William M Schneider, Olga Katsara, Gisselle N Medina, Ashley Fisher, Aishwarya Mogulothu, Yingpu Yu, Meigang Gu, Teresa de los Santos, Robert J Schneider, Meike Dittmann
Publikováno v:
EMBO reports. 23
Co-opting host cell protein synthesis is a hallmark of many virus infections. In response, certain host defense proteins limit mRNA translation globally, albeit at the cost of the host cell's own protein synthesis. Here, we describe an interferon-sti
Autor:
Mohammad Sadic, William M. Schneider, Olga Katsara, Gisselle N. Medina, Aishwarya Mogulothu, Yingpu Yu, Meigang Gu, Teresa de los Santos, Robert J. Schneider, Meike Dittmann
During viral infection, competition ensues between viruses and their host cells to control the protein synthesis machinery. In response, certain host defense proteins globally limit mRNA translation. However, this is also detrimental for host protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f35e01ce0ae2fc4b32f05e1edc52da2
https://doi.org/10.1101/2022.02.08.479557
https://doi.org/10.1101/2022.02.08.479557
Autor:
Charles M. Rice, Margaret R. MacDonald, Inês M. B. Veiga, Javier Fernandez-Martinez, Bettina Salome Trüeb, Avery Peace, Joseph M. Luna, Eleftherios Michailidis, Tran Thi Nhu Thao, Paul D. Bieniasz, Francisco J. Sánchez-Rivera, Theodora Hatziioannou, Volker Thiel, H.-Heinrich Hoffmann, Fabian Schmidt, Scott W. Lowe, Yingpu Yu, Brandon S. Razooky, Inna Ricardo-Lax, Michael P. Rout, William M. Schneider, Nadine Ebert, Yiska Weisblum, Jérémie Le Pen, Kimberly Schmied, John T. Poirier
Publikováno v:
Science
Ricardo-Lax, Inna; Luna, Joseph M; Tran, Thi Nhu Thao; Le Pen, Jérémie; Yu, Yingpu; Hoffmann, H-Heinrich; Schneider, William M; Razooky, Brandon S; Fernandez-Martinez, Javier; Schmidt, Fabian; Weisblum, Yiska; Trüeb, Bettina Salome; Berenguer Veiga, Inês; Schmied, Kimberly; Ebert, Nadine; Michailidis, Eleftherios; Peace, Avery; Sánchez-Rivera, Francisco J; Lowe, Scott W; Rout, Michael P; ... (2021). Replication and single-cycle delivery of SARS-CoV-2 replicons. Science, 374(6571), pp. 1099-1106. American Association for the Advancement of Science 10.1126/science.abj8430
Ricardo-Lax, Inna; Luna, Joseph M; Tran, Thi Nhu Thao; Le Pen, Jérémie; Yu, Yingpu; Hoffmann, H-Heinrich; Schneider, William M; Razooky, Brandon S; Fernandez-Martinez, Javier; Schmidt, Fabian; Weisblum, Yiska; Trüeb, Bettina Salome; Berenguer Veiga, Inês; Schmied, Kimberly; Ebert, Nadine; Michailidis, Eleftherios; Peace, Avery; Sánchez-Rivera, Francisco J; Lowe, Scott W; Rout, Michael P; ... (2021). Replication and single-cycle delivery of SARS-CoV-2 replicons. Science, 374(6571), pp. 1099-1106. American Association for the Advancement of Science 10.1126/science.abj8430
A tool to study SARS-CoV-2 Work with infectious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) requires high-level biocontainment facilities, making it important to develop safer molecular tools that can potentially be used under less s
Autor:
Zhenlan Yao, Charles M. Rice, Danyang Gong, Melody M. H. Li, John T. Poirier, William M. Schneider, Stephanie A. Azzopardi, Hengli Tang, Margaret R. MacDonald, H.-Heinrich Hoffmann, Leonia Bozzacco, Sangeetha Ramachandran, Ren Sun, Robert Damoiseaux, Charles M. Rudin, Anh Phuong Luu, Linde A. Miles, Gustavo Garcia, Vaithilingaraja Arumugaswami, Kouki Morizono
Publikováno v:
Viruses, Vol 13, Iss 2113, p 2113 (2021)
Viruses
Volume 13
Issue 11
Viruses
Volume 13
Issue 11
Zika virus (ZIKV) is a re-emerging flavivirus that has caused large-scale epidemics. Infection during pregnancy can lead to neurologic developmental abnormalities in children. There is no approved vaccine or therapy for ZIKV. To uncover cellular path
Autor:
Xianfang Wu, Ashley Acevedo, Jiayi Wang, Brian Hurwitz, Charles M. Rice, Hachung Chung, William M. Schneider, Tony Sun, Yingpu Yu, Brad R. Rosenberg, Ji-Dung Luo
Publikováno v:
Proc Natl Acad Sci U S A
Human adenosine deaminase acting on RNA 1 (ADAR1) catalyzes adenosine-to-inosine deamination reactions on double-stranded RNA molecules to regulate cellular responses to endogenous and exogenous RNA. Defective ADAR1 editing leads to disorders such as
Autor:
Charles M. Rudin, Linde A. Miles, Charles M. Rice, Laura K. McMullan, Xianfang Wu, John T. Poirier, Kathryn Rozen-Gagnon, Soon Yi, Margaret R. MacDonald, Eliana Jacobson, Brandon S. Razooky, Felix Schuster, H.-Heinrich Hoffmann, William M. Schneider
Publikováno v:
Cell
bioRxiv
article-version (status) pre
article-version (number) 2
bioRxiv
article-version (status) pre
article-version (number) 2
Flaviviruses pose a constant threat to human health. These RNA viruses are transmitted by the bite of infected mosquitoes and ticks and regularly cause outbreaks. To identify host factors required for flavivirus infection, we performed full-genome lo