Zobrazeno 1 - 10
of 566
pro vyhledávání: '"William M Lee"'
Autor:
Tran Nguyen, Robert Gish, Binh T Nguyen, Amy Trang, Trang Pham, Hong K Tang, Loc Phan, Gary Mize, William M Lee, Anh Le, Hai T Phan, Doan Y Dao
Publikováno v:
BMJ Open, Vol 11, Iss 10 (2021)
Externí odkaz:
https://doaj.org/article/430ae58eca3348f3b4fca49e44ef1908
Autor:
Zhao Shan, Leike Li, Constance Lynn Atkins, Meng Wang, Yankai Wen, Jongmin Jeong, Nicolas F Moreno, Dechun Feng, Xun Gui, Ningyan Zhang, Chun Geun Lee, Jack A Elias, William M Lee, Bin Gao, Fong Wilson Lam, Zhiqiang An, Cynthia Ju
Publikováno v:
eLife, Vol 10 (2021)
Background: Hepatic platelet accumulation contributes to acetaminophen (APAP)-induced liver injury (AILI). However, little is known about the molecular pathways involved in platelet recruitment to the liver and whether targeting such pathways could a
Externí odkaz:
https://doaj.org/article/87bb9242be7e4ea1a0cab9c6806e6563
Autor:
Herbert L Bonkovsky, Huiman X Barnhart, David M Foureau, Nury Steuerwald, William M Lee, Jiezhun Gu, Robert J Fontana, Paul H Hayashi, Naga Chalasani, Victor M Navarro, Joseph Odin, Andrew Stolz, Paul B Watkins, Jose Serrano, US Drug-Induced Liver Injury Network and the Acute Liver Failure Study Group
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212394 (2019)
[This corrects the article DOI: 10.1371/journal.pone.0206389.].
Externí odkaz:
https://doaj.org/article/c3526bba37924bbf8be75f5fee6b4a60
Autor:
Herbert L Bonkovsky, Huiman X Barnhart, David M Foureau, Nury Steuerwald, William M Lee, Jiezhun Gu, Robert J Fontana, Paul J Hayashi, Naga Chalasani, Victor M Navarro, Joseph Odin, Andrew Stolz, Paul B Watkins, Jose Serrano, US Drug-Induced Liver Injury Network and the Acute Liver Failure Study Group
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0206389 (2018)
Changes in levels of cytokines and chemokines have been proposed as possible biomarkers of tissue injury, including liver injury due to drugs. Recently, in acute drug-induced liver injury (DILI), we showed that 19 of 27 immune analytes were different
Externí odkaz:
https://doaj.org/article/2b7e720581cc4865b744d7229e871314
Autor:
Oren K Fix, Iris Liou, Constantine J Karvellas, Daniel R Ganger, Kimberly A Forde, Ram M Subramanian, Alice Boylan, James Hanje, R Todd Stravitz, William M Lee, Acute Liver Failure Study Group
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155500 (2016)
INTRODUCTION:Acute liver failure (ALF) is an ideal condition for use of a checklist. Our aims were to develop a checklist for the management of ALF in the intensive care unit (ICU) and assess the usability of the checklist among multiple providers. M
Externí odkaz:
https://doaj.org/article/5bab0f22285a4798a2eac178d10e6e4f
Autor:
Jody A Rule, Linda S Hynan, Nahid Attar, Corron Sanders, William J Korzun, William M Lee, Acute Liver Failure Study Group
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138566 (2015)
Because acute liver failure (ALF) patients share many clinical features with severe sepsis and septic shock, identifying bacterial infection clinically in ALF patients is challenging. Procalcitonin (PCT) has proven to be a useful marker in detecting
Externí odkaz:
https://doaj.org/article/ea3505d02f6a450c88059ff83b6cac18
Autor:
Gurnit Kaur, Elaine M Leslie, Holly Tillman, William M Lee, Diane P Swanlund, Constantine J Karvellas, US Acute Liver Failure Study Group
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0139299 (2015)
Acetaminophen (APAP) hepatotoxicity is related to the formation of N-acetyl-p-benzoquinone imine (NAPQI), which is detoxified through conjugation with reduced glutathione (GSH). Ophthalmic acid (OA) is an analogue of GSH in which cysteine is replaced
Externí odkaz:
https://doaj.org/article/b3eb308a2ca34edcbfa0766ac36c8a32
Autor:
Jaime Lynn Speiser, William M Lee, Constantine J Karvellas, US Acute Liver Failure Study Group
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0122929 (2015)
Assessing prognosis for acetaminophen-induced acute liver failure (APAP-ALF) patients often presents significant challenges. King's College (KCC) has been validated on hospital admission, but little has been published on later phases of illness. We a
Externí odkaz:
https://doaj.org/article/0df5f6cb352a43bcae9da1b9889f9c29
Autor:
Nury M Steuerwald, David M Foureau, H James Norton, Jie Zhou, Judith C Parsons, Naga Chalasani, Robert J Fontana, Paul B Watkins, William M Lee, K Rajender Reddy, Andrew Stolz, Jayant Talwalkar, Timothy Davern, Dhanonjoy Saha, Lauren N Bell, Huiman Barnhart, Jiezhun Gu, Jose Serrano, Herbert L Bonkovsky
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81974 (2013)
Drug-induced liver injury (DILI) is the most common cause of acute liver failure in the United-States. The aim of the study was to describe serum immune profiles associated with acute DILI, to investigate whether there are profiles associated with cl
Externí odkaz:
https://doaj.org/article/d768e5b0af76443280e55dea3cf693f0
Autor:
Long Xu, Yang Yang, Yankai Wen, Jong-Min Jeong, Christoph Emontzpohl, Constance L. Atkins, Zhaoli Sun, Kyle L. Poulsen, David R. Hall, J. Steve Bynon, Bin Gao, William M. Lee, Jody Rule, Elizabeth A. Jacobsen, Hua Wang, Cynthia Ju
Publikováno v:
Journal of Hepatology. 77:344-352
Beyond the classical description of eosinophil functions in parasite infections and allergic diseases, emerging evidence supports a critical role of eosinophils in resolving inflammation and promoting tissue remodeling. However, the role of eosinophi