Zobrazeno 1 - 10
of 19
pro vyhledávání: '"William M, Hanes"'
Autor:
Florian Missey, Malin Silverå Ejneby, Ibrahima Ngom, Mary J. Donahue, Jan Trajlinek, Emma Acerbo, Boris Botzanowski, Antonino M. Cassarà, Esra Neufeld, Eric D. Glowacki, Lee Shangold, William M. Hanes, Adam Williamson
Publikováno v:
Bioelectronic Medicine, Vol 9, Iss 1, Pp 1-12 (2023)
Abstract Background Peripheral nerve stimulation is used in both clinical and fundamental research for therapy and exploration. At present, non-invasive peripheral nerve stimulation still lacks the penetration depth to reach deep nerve targets and th
Externí odkaz:
https://doaj.org/article/9d5f744917da4097ba726769930cc9ca
Autor:
Jia Feng, Haichan Xu, Andrew Cinquina, Zehua Wu, Wenli Zhang, Lihua Sun, Qi Chen, Lei Tian, Le Song, Kevin G. Pinz, Masayuki Wada, Xun Jiang, William M. Hanes, Yupo Ma, Hongyu Zhang
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
T-cell lymphomas are aggressive lymphomas that often resist current therapy options or present with relapsed disease, making the development of more effective treatment regimens clinically important. Previously, we have shown that CD4 CAR can effecti
Externí odkaz:
https://doaj.org/article/52eee73e480b4c79872209d7c637ada0
Autor:
William M. Hanes, Peder S. Olofsson, Sébastien Talbot, Tea Tsaava, Mahendar Ochani, Gavin H. Imperato, Yaakov A. Levine, Jesse Roth, Maud A. Pascal, Simmie L. Foster, Ping Wang, Clifford Woolf, Sangeeta S. Chavan, Kevin J. Tracey
Publikováno v:
Bioelectronic Medicine, Vol 3, Iss 1, Pp 18-28 (2016)
Abstract When pathogens and toxins breech the epithelial barrier, antigens are transported by the lymphatic system to lymph nodes. In previously immunized animals, antigens become trapped in the draining lymph nodes, but the underlying mechanism that
Externí odkaz:
https://doaj.org/article/8f137ba9aa14424085f47f2d54f4ca51
Autor:
LaQueta K Hudson, Meghan E Dancho, Jianhua Li, Johanna B Bruchfeld, Ahmed A Ragab, Mingzhu M He, Meaghan Bragg, Delaney Lenaghan, Michael D Quinn, Jason R Fritz, Matthew V Tanzi, Harold A Silverman, William M Hanes, Yaakov A Levine, Valentin A Pavlov, Peder S Olofsson, Jesse Roth, Yousef Al-Abed, Ulf Andersson, Kevin J Tracey, Sangeeta S Chavan
Publikováno v:
Molecular Medicine, Vol 22, Iss 1, Pp 585-596 (2016)
Abstract Type 1 diabetes mellitus (T1D) is a chronic autoimmune disease characterized by β cell destruction, insulin deficiency and hyperglycemia. Activated macrophages and autoimmune T cells play a crucial role in the pathogenesis of hyperglycemia
Externí odkaz:
https://doaj.org/article/1b503e667e7a4316a65cb45047598dd9
Autor:
Laura Tarnawski, Colin Reardon, April S. Caravaca, Mauricio Rosas-Ballina, Michael W. Tusche, Anna R. Drake, LaQueta K. Hudson, William M. Hanes, Jian Hua Li, William R. Parrish, Kaie Ojamaa, Yousef Al-Abed, Michael Faltys, Valentin A. Pavlov, Ulf Andersson, Sangeeta S. Chavan, Yaakov A. Levine, Tak W. Mak, Kevin J. Tracey, Peder S. Olofsson
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Macrophage cytokine production is regulated by neural signals, for example in the inflammatory reflex. Signals in the vagus and splenic nerves are relayed by choline acetyltransferase+ T cells that release acetylcholine, the cognate ligand for alpha7
Externí odkaz:
https://doaj.org/article/52bcfec8bc364d5ab8731c82b886af1a
Autor:
Masayuki Wada, Lei Xu, Li-hua Sun, Hongyu Zhang, William M Hanes, Jia Feng, Huiming Shan, Qian Zhang, Kevin G. Pinz, Zehua Wu, Xingen Wang, Yupo Ma, Wenli Zhang, Andrew Cinquina, Xun Jiang, Ping Zhang, Qi Chen, Haichan Xu
Publikováno v:
Stem Cell Reviews and Reports
While treatment for B-cell malignancies has been revolutionized through the advent of CAR immunotherapy, similar strategies for T-cell malignancies have been limited. Additionally, T-cell leukemias and lymphomas can commonly metastasize to the CNS, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c803873f2aac18f823eead295fb8c12d
https://pubmed.ncbi.nlm.nih.gov/33410096
https://pubmed.ncbi.nlm.nih.gov/33410096
Autor:
William Tse, Yi Su, Yecheng Li, Yisong Xiong, Guangcui He, Sha Sha, Fang Liu, William M Hanes, Gina Ma
Publikováno v:
Stem cell reviews and reports. 16(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01c73342daca942ded83144618b812f5
https://pubmed.ncbi.nlm.nih.gov/32840736
https://pubmed.ncbi.nlm.nih.gov/32840736
Autor:
Peder S. Olofsson, Simmie L. Foster, Gavin H Imperato, William M Hanes, Kevin J. Tracey, Tea Tsaava, Sangeeta S. Chavan, Clifford J. Woolf, Jesse Roth, Sébastien Talbot, Ping Wang, Yaakov A. Levine, Mahendar Ochani, Maud Pascal
Publikováno v:
Bioelectronic Medicine, Vol 3, Iss 1, Pp 18-28 (2016)
Bioelectron Med
Bioelectron Med
When pathogens and toxins breech the epithelial barrier, antigens are transported by the lymphatic system to lymph nodes. In previously immunized animals, antigens become trapped in the draining lymph nodes, but the underlying mechanism that controls
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::423c8ff22f9c6e322e0acc6cac97c69d
http://link.springer.com/article/10.15424/bioelectronmed.2016.00001
http://link.springer.com/article/10.15424/bioelectronmed.2016.00001
Autor:
William M Hanes, Sangeeta S. Chavan, Betty Diamond, Nichol E. Holodick, Anders Arner, Andrea Introini, Ferenc Szekeres, Roozbeh Sobbi, Michaela Oswald, Thomas L. Rothstein, Cecilia Lövdahl, Shu Fang Liu, Edmund J. Miller, Huan Yang, Valentin A. Pavlov, Benjamin E. Steinberg, Tak W. Mak, Peter K. Gregersen, Ulf Andersson, Kristina Broliden, Peter H. Backx, Kevin J. Tracey, Peder S. Olofsson, Maureen A. Cox, Mohamed Ahmed
Publikováno v:
Nature Biotechnology. 34:1066-1071
Blood pressure regulation is known to be maintained by a neuro-endocrine circuit, but whether immune cells contribute to blood pressure homeostasis has not been determined. We previously showed that CD4+ T lymphocytes that express choline acetyltrans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55935650517e1792b6b194e2a59f3606
https://doi.org/10.1038/nbt.3663
https://doi.org/10.1038/nbt.3663
Autor:
Yaakov A. Levine, William M Hanes, Valentin A. Pavlov, Jesse Roth, Sangeeta S. Chavan, Jason R. Fritz, Johanna B Bruchfeld, Michael D Quinn, Mingzhu M He, Harold A. Silverman, Kevin J. Tracey, Ulf Andersson, Peder S. Olofsson, LaQueta K Hudson, Ahmed A. Ragab, Matthew V Tanzi, Yousef Al-Abed, Meghan Dancho, Jianhua Li, Meaghan Bragg, Delaney Lenaghan
Publikováno v:
Molecular Medicine, Vol 22, Iss 1, Pp 585-596 (2016)
Type 1 diabetes mellitus (T1D) is a chronic autoimmune disease characterized by β cell destruction, insulin deficiency and hyperglycemia. Activated macrophages and autoimmune T cells play a crucial role in the pathogenesis of hyperglycemia in NOD mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e57afa216eaa05fcbdd981124681813b
https://doi.org/10.2119/molmed.2016.00082
https://doi.org/10.2119/molmed.2016.00082