Zobrazeno 1 - 10
of 11
pro vyhledávání: '"William Lautert-Dutra"'
Autor:
William Lautert-Dutra, Camila M. Melo, Luiz P. Chaves, Cheryl Crozier, Fabiano P. Saggioro, Rodolfo B. dos Reis, Jane Bayani, Sandro L. Bonatto, Jeremy A. Squire
Publikováno v:
Molecular Cytogenetics, Vol 17, Iss 1, Pp 1-19 (2024)
Abstract Background In prostate cancer (PCa), well-established biomarkers such as MSI status, TMB high, and PDL1 expression serve as reliable indicators for favorable responses to immunotherapy. Recent studies have suggested a potential association b
Externí odkaz:
https://doaj.org/article/506ccc0825c94ba5a2768f71738573d5
Autor:
William Lautert-Dutra, Camila Morais Melo, Luiz Paulo Chaves, Francisco Cesar Sousa, Cheryl Crozier, Dan Dion, Filipe S. Avante, Fabiano Pinto Saggioro, Rodolfo Borges dos Reis, Leticia Fröhlich Archangelo, Jane Bayani, Jeremy A. Squire
Publikováno v:
Cancers, Vol 16, Iss 8, p 1480 (2024)
Prostate cancer (PCa) is an immunologically cold tumor and the molecular processes that underlie this behavior are poorly understood. In this study, we investigated a primary cohort of intermediate-risk PCa (n = 51) using two NanoString profiling pan
Externí odkaz:
https://doaj.org/article/52002b0b87c140f8a4baf6cf34e21906
Autor:
William Lautert-Dutra, Camila M. Melo, Luiz P. Chaves, Francisco C. Souza, Cheryl Crozier, Adam E. Sundby, Elizabeth Woroszchuk, Fabiano P. Saggioro, Filipe S. Avante, Rodolfo B. dos Reis, Jeremy A. Squire, Jane Bayani
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
The diverse clinical outcomes of prostate cancer have led to the development of gene signature assays predicting disease progression. Improved prostate cancer progression biomarkers are needed as current RNA biomarker tests have varying success for i
Externí odkaz:
https://doaj.org/article/a1fb79af93bd4f06adfa1592578150c9
Autor:
Camila Morais Melo, Thiago Vidotto, Luiz Paulo Chaves, William Lautert-Dutra, Rodolfo Borges dos Reis, Jeremy Andrew Squire
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9550 (2021)
Immunotherapy has improved patient survival in many types of cancer, but for prostate cancer, initial results with immunotherapy have been disappointing. Prostate cancer is considered an immunologically excluded or cold tumor, unable to generate an e
Externí odkaz:
https://doaj.org/article/17e04779afec4784bc38e0490f5c09ee
Publikováno v:
British Journal of Cancer.
Autor:
William Lautert-Dutra, Camila M. Melo, Luiz P. Chaves, Cheryl Crozier, Fabiano P. Saggioro, Rodolfo B. dos Reis, Jane Bayani, Sandro L. Bonatto, Jeremy A. Squire
BackgroundCDK12 inactivation is a predictive biomarker for immune checkpoint blockers (ICB) treatment response in advanced prostate cancer (PCa), but some CDK12-altered patients fail to respond to ICB. Downregulation of MHC expression has been descri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e4475b778923010f582d8950a97922d
https://doi.org/10.1101/2022.04.16.487364
https://doi.org/10.1101/2022.04.16.487364
Autor:
William Lautert-Dutra, Camila Morais Melo, Luiz Paulo Chaves, André Luiz Caliari, Francisco Cesar Souza Silva, Jeremy Andrew Squire
Publikováno v:
Cancer Research. 82:6099-6099
Prostate Cancer (PCa) is considered an immunologically excluded tumor, unable to generate an effective T-cell response against cancer cells. Inactivating mutations of the PTEN tumor suppressor are one of the most common events in human malignancies t
Autor:
Luiz Paulo Chaves, André Luiz Caliari, William Lautert-Dutra, Francisco Cesar Souza Silva, Camila Morais Melo, Fabiano Pinto Saggioro, Rodolfo Borges dos Reis, Jeremy Andrew Squire
Publikováno v:
Cancer Research. 82:6098-6098
Prostate cancer (PCa) reactivates a latent embryonic program called epithelial-mesenchymal transition during disease progression. The mesenchymal phenotype contributes to invasion, metastasis and therapy response variation. In this study, we characte
Autor:
Rodolfo Borges dos Reis, Jeremy A. Squire, Luiz Paulo Chaves, Thiago Vidotto, William Lautert-Dutra, Camila Morais Melo
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
International Journal of Molecular Sciences, Vol 22, Iss 9550, p 9550 (2021)
International Journal of Molecular Sciences
Universidade de São Paulo (USP)
instacron:USP
International Journal of Molecular Sciences, Vol 22, Iss 9550, p 9550 (2021)
International Journal of Molecular Sciences
Immunotherapy has improved patient survival in many types of cancer, but for prostate cancer, initial results with immunotherapy have been disappointing. Prostate cancer is considered an immunologically excluded or cold tumor, unable to generate an e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b833ce6b7e73a2330bab52c3a0b383ea
Autor:
Talita Carneiro Brandão Pereira, William Lautert-Dutra, Karine Batista dos Santos, Ivo André Homrich Schneider, Lilian de Souza Teodoro, Vítor Otacílio de Almeida, Jéssica Weiler, Maurício Reis Bogo
Publikováno v:
Chemosphere. 266:129350