Zobrazeno 1 - 10
of 65
pro vyhledávání: '"William L. Trepicchio"'
Publikováno v:
Journal of Immunology Research, Vol 2016 (2016)
Numbers of biotherapeutic products in development have increased over past decade. Despite providing significant benefits to patients with unmet needs, almost all protein-based biotherapeutics could induce unwanted immunogenicity, which result in a l
Externí odkaz:
https://doaj.org/article/dc9621aeabd94c25a5359e24ac033833
Autor:
Hongyu Zhao, Kurt A Schalper, Konstantinos Syrigos, Adam Aguirre-Ducler, Nicole Gianino, Franz Villarroel-Espindola, Shruti Desai, Daiwei Tang, William L Trepicchio, Karuppiah Kannan, Richard C Gregory
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 7 (2022)
Background The expression of SYK in cancer cells has been associated with both tumor promoting and tumor suppressive effects. Despite being proposed as anticancer therapeutic target, the possible role of SYK in modulating local adaptive antitumor imm
Externí odkaz:
https://doaj.org/article/226cd00e288a459e9d9ceadc7c706a91
Autor:
Hadi Danaee, Thea Kalebic, Timothy Wyant, Matteo Fassan, Claudia Mescoli, Feng Gao, William L Trepicchio, Massimo Rugge
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189953 (2017)
The transmembrane receptor guanylate cyclase-C (GCC) has been found to be expressed in colorectal cancers. However, limited data are available on GCC protein expression in non-colorectal gastrointestinal tumors and few studies have reported whether G
Externí odkaz:
https://doaj.org/article/076edc77f43846c386adc6a52620dd06
Autor:
Adam Aguirre-Ducler, Nicole Gianino, Franz Villarroel-Espindola, Shruti Desai, Daiwei Tang, Hongyu Zhao, Konstantinos Syrigos, William L Trepicchio, Karuppiah Kannan, Richard C Gregory, Kurt A Schalper
Publikováno v:
Journal for immunotherapy of cancer. 10(7)
BackgroundThe expression of SYK in cancer cells has been associated with both tumor promoting and tumor suppressive effects. Despite being proposed as anticancer therapeutic target, the possible role of SYK in modulating local adaptive antitumor immu
Publikováno v:
Biomarkers in Drug Discovery and Development
Autor:
Meredith Little, Lisa Brown, José Antonio Sanches, Pietro Quaglino, J. Scarisbrick, Oliver Bechter, Kerry Taylor, David E. Fisher, Matthew Onsum, M. Corinna Palanca-Wessels, Veronica Bunn, Pascal Wolter, Steven M. Horwitz, Jan Walewski, Judith Trotman, Madeleine Duvic, Rudolf Stadler, Lauren C. Pinter-Brown, Herbert Eradat, Reinhard Dummer, Pier Luigi Zinzani, Marise McNeeley, Sean Whittaker, Alejandro A. Gru, Pablo L. Ortiz-Romero, Julie Lisano, H. Miles Prince, Michael Weichenthal, Youn H. Kim, William L. Trepicchio, Oleg E. Akilov
INTRODUCTION: Mycosis fungoides (MF), the most common type of cutaneous T-cell lymphoma, can lead to disfiguring lesions, debilitating pruritus and frequent skin infections. This study assessed response to brentuximab vedotin in patients with MF in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad3b61df0e6864ee0a19d3ccb015c2ca
https://lirias.kuleuven.be/handle/123456789/674933
https://lirias.kuleuven.be/handle/123456789/674933
Autor:
Steven M. Horwitz, Árpád Illés, Pier Luigi Zinzani, David Belada, Tatyana Feldman, Andreas Huettmann, Owen A. O'Connor, Hervé Tilly, Timothy M Illidge, Won Seog Kim, Nancy L. Bartlett, Eric D. Jacobsen, M. Onsum, Swaminathan Padmanabhan Iyer, Ranjana H. Advani, Harry H. Miao, Thomas Manley, Shangbang Rao, William L. Trepicchio
Publikováno v:
Hematological Oncology. 37:281-283
7538 Background: Brentuximab vedotin (BV) is an antibody-drug conjugate that targets CD30. The ECHELON-2 (E-2) study demonstrated significantly longer progression-free and overall survival with BV plus cyclophosphamide, doxorubicin, and prednisone (A
Autor:
H Miles Prince, Youn H Kim, Steven M Horwitz, Reinhard Dummer, Julia Scarisbrick, Pietro Quaglino, Pier Luigi Zinzani, Pascal Wolter, Jose A Sanches, Pablo L Ortiz-Romero, Oleg E Akilov, Larisa Geskin, Judith Trotman, Kerry Taylor, Stephane Dalle, Michael Weichenthal, Jan Walewski, David Fisher, Brigitte Dréno, Rudolf Stadler, Tatyana Feldman, Timothy M Kuzel, Yinghui Wang, Maria Corinna Palanca-Wessels, Erin Zagadailov, William L Trepicchio, Wenwen Zhang, Hui-Min Lin, Yi Liu, Dirk Huebner, Meredith Little, Sean Whittaker, Madeleine Duvic, David Joske, H. Miles Prince, Ian D. Lewis, Constanze Jonak, Franz Trautinger, Oliver Bechter, Dominique Bron, Vladmir Claudio C. de Lima, Jose Antonio Sanches, Richard Klasa, Martine Bagot, Marie Beylot-Barry, Michel D'Incan, Brigitte Dreno, Florent Grange, Jan Nicolay, Marion Wobser, Chalid Assaf, Carmen Loquai, Michele Spina, Alberto Bosi, Pier Paolo Fattori, Aleksandra Grzanka, Andres Lopez-Hernandez, Pablo L. Ortiz-Romero, Jose Juan Rifon Roca, Silvana Novelli Canales, Timothy Illidge, Rod Johnson, Stephen Morris, Pam McKay, Oleg Akilov, Steve Horwitz, Youn H. Kim, Barbara Pro, Timothy Kuzel, Adam Lerner, Herbert Eradat, Lubomir Sokol, David C. Fisher, Sarah Hughey
Publikováno v:
The Lancet. 390:555-566
Cutaneous T-cell lymphomas are rare, generally incurable, and associated with reduced quality of life. Present systemic therapies rarely provide reliable and durable responses. We aimed to assess efficacy and safety of brentuximab vedotin versus conv
Autor:
William L. Trepicchio, Rachael Liu, Jean M. Connors, Anna Sureda, Ruth Pettengell, S. Kuroda, Neil C Josephson, W.S. Kim, John Radford, M. Onsum, Nagesh Kalakonda, Ashish Gautam, Mark S. Kaminski, Andrea Gallamini, Anas Younes, S. M. Ansell, Ian W. Flinn, Harry Miao, June-Won Cheong
Publikováno v:
Hematological Oncology. 37:290-291
Autor:
Feng Gao, Claudia Mescoli, Thea Kalebic, Massimo Rugge, William L. Trepicchio, Matteo Fassan, Tim Wyant, Hadi Danaee
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 12, p e0189953 (2017)
PLoS ONE, Vol 12, Iss 12, p e0189953 (2017)
Background The transmembrane receptor guanylate cyclase-C (GCC) has been found to be expressed in colorectal cancers. However, limited data are available on GCC protein expression in non-colorectal gastrointestinal tumors and few studies have reporte