Zobrazeno 1 - 7
of 7
pro vyhledávání: '"William L. Schary"'
Autor:
Anna-Maria Fink, Maneesh Tandon, Cll Study Investigators, Karl Anton Kreuzer, Arijit Sinha, Eugen Tausch, Matthias Ritgen, Kirsten Fischer, Sandra Robrecht, Barbara Eichhorst, William L. Schary, Can Zhang, Stephan Stilgenbauer, Clemens M. Wendtner, Michael Hallek, Othman Al-Sawaf
Publikováno v:
Journal of Clinical Oncology. 38:8027-8027
8027 Background: The CLL14 trial demonstrated significant improvement of progression-free survival (PFS) with fixed-duration venetoclax-obinutuzumab (VenG) as compared to chlorambucil-obinutuzumab (ClbG) in patients with previously untreated CLL and
Autor:
Irma H. Benedek, Allison M. Agra, Shang-Ying P. King, William L. Schary, Henry J. Pieniaszek, Richard J. Powell
Publikováno v:
The Journal of Clinical Pharmacology. 32:558-563
Moricizine HCl, a new orally active antiarrhythmic agent, induces its own hepatic metabolism and consequently may interfere with the metabolism of warfarin, a drug used commonly by cardiac patients that also is subject to extensive hepatic metabolism
An in vitro study of drug displacement interactions: warfarin-salicylate and warfarin-phenylbutazone
Publikováno v:
Journal of Pharmacy and Pharmacology. 31:322-330
The binding interactions between warfarin-salicylate and warfarin-phenylbutazone in the presence of 4 g percent bovine serum albumin at 37 °C were studied using equilibrium dialysis. Methods of representing and analysing drug binding interactions ar
Publikováno v:
The Journal of Clinical Pharmacology. 27:866-873
The pharmacokinetics of intravenous and oral nalbuphine were studied in 24 healthy male volunteers ranging in age from 21 to 30 years. On separate test days over a five-week period, subjects received single doses of each of four different formulation
Publikováno v:
Journal of Pharmaceutical Sciences. 73:485-488
A three-way crossover study was conducted with 24 healthy male volunteers to determine the relative bioavailability of four different 100-mg phenobarbital tablets compared with a reference elixir. Each subject received two of the tablets and the elix
Autor:
Kenneth L. Melmon, Peter J. Meffin, William L. Schary, Roger L. Williams, Terrence F. Blaschke, Malcolm Rowland
Publikováno v:
Clinical pharmacology and therapeutics. 20(1)
Five patients received a small oral dose of warfarin during and after recovery from acute viral hepatitis. Mean (+/- SD) clearance, volume of distribution, and half-life of the drug were 6.1 +/- 0.9 ml/hr/kg, 0.09 +/- 0.04 L/kg, and 23 +/- 5 hr, resp
Autor:
Malcolm Rowland, William L. Schary
Publikováno v:
Journal of pharmacokinetics and biopharmaceutics. 11(3)
The influence of altered drug binding on the hepatic elimination of tolbutamide, a drug of low intrinsic clearance, and on the formation of its metabolite, hydroxytolbutamide, was examined under linear conditions at steady state in the isolated in si