Zobrazeno 1 - 10
of 97
pro vyhledávání: '"William L. Pak"'
Autor:
Baruch Minke, William L. Pak
Publikováno v:
Journal of neurogenetics. 36(2-3)
The
Autor:
Parvin Shahrestani, Hung-Tat Leung, Phung Khanh Le, William L Pak, Stephanie Tse, Karen Ocorr, Taosheng Huang
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6867 (2009)
Optic Atrophy 1 (OPA1) is a ubiquitously expressed dynamin-like GTPase in the inner mitochondrial membrane. It plays important roles in mitochondrial fusion, apoptosis, reactive oxygen species (ROS) and ATP production. Mutations of OPA1 result in aut
Externí odkaz:
https://doaj.org/article/f794f086e7074a02a6c6341de91e1c39
Publikováno v:
The Oxford Handbook of Neuronal Ion Channels ISBN: 9780190669164
The Drosophila Transient Receptor Potential (TRP) channel is the founding member of a large and diverse family of channel proteins. These channels are evolutionarily conserved from yeast to mammals and are found in many organisms and tissues. The TRP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4189fdb15ec82343ec500156cfd8e50
https://doi.org/10.1093/oxfordhb/9780190669164.013.5
https://doi.org/10.1093/oxfordhb/9780190669164.013.5
Autor:
Gustafson Gary D, Jim M. Gifford, Ignacio Larrinua, Thomas C. Sparks, Scott Chouinard, Gerald B. Watson, Jon C. Mitchell, Ted Letherer, Vincent L. Salgado, James M. Hasler, William L. Pak, Chaoxian Geng, Kevin R. Cook, Geoff E. Stilwell
Publikováno v:
Insect Biochemistry and Molecular Biology. 40:376-384
Strains of Drosophila melanogaster with resistance to the insecticides spinosyn A, spinosad, and spinetoram were produced by chemical mutagenesis. These spinosyn-resistant strains were not cross-resistant to other insecticides. The two strains that w
Publikováno v:
Journal of Biological Chemistry. 284:11100-11109
Ca2+ modulates the visual response in both vertebrates and invertebrates. In Drosophila photoreceptors, an increase of cytoplasmic Ca2+ mimics light adaptation. Little is known regarding the mechanism, however. We explored the role of the sole Drosop
Autor:
A. Ashleigh Long, Lingling An, Eunju Kim, William L. Pak, Rebecca W. Doerge, Kendal Broadie, Elvin Woodruff, Hung Tat Leung
Publikováno v:
The Journal of Neuroscience. 28:3668-3682
A systematic forward geneticDrosophilascreen for electroretinogram mutants lacking synaptic transients identified thefuseless(fusl) gene, which encodes a predicted eight-pass transmembrane protein in the presynaptic membrane. Nullfuslmutants display
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1674:91-97
RNA interference has been widely used to reduce the quantity of the proteins encoded by the targeted genes. A constitutively active, dominant allele of trp, TrpP365, causes massive degeneration of photoreceptors through a persistent and excessive Ca2
Autor:
Chaoxian Geng, Younkyung Kim, Jaeseung Yoon, Seunghee Lee, William L. Pak, Hung-Tat Leung, Kwanghee Baek
Publikováno v:
Journal of Neurochemistry. 89:998-1008
A large number of mutants in the norpA gene, which encodes the phospholipase C (PLC) involved in Drosophila phototransduction, is available for the investigation of the effects of specific amino acid substitutions in PLC on biochemical and electrophy
Autor:
Hung-Tat Leung, William L. Pak
Publikováno v:
Receptors and Channels. 9:149-167
Because almost everything we know about Drosophila phototransduction has come from studies based on genetic approaches, this review begins with a discussion of genetic approaches. We then present a brief overview of Drosophila phototransduction (sect
Autor:
So-Yeon Park, Jaeseung Yoon, John Bowman, Young S. Hong, William L. Pak, Kwanghee Baek, Chaoxian Geng
Publikováno v:
Journal of Biological Chemistry. 277:33884-33889
The trp gene encodes subunits of a highly Ca(2+)-permeable class of light-activated channels of Drosophila photoreceptors. The recently characterized mutation in this gene, Trp(P365), is semidominant and causes massive degeneration of photoreceptors