Zobrazeno 1 - 10
of 18
pro vyhledávání: '"William L. Neeley"'
Publikováno v:
Tissue Engineering Part A. 17:1675-1682
Retinal transplantation experiments have advanced considerably during recent years, but remaining diseased photoreceptor cells in the host retina physically obstruct the development of graft–host neuronal contacts that are required for vision. We h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::529ac8d7e218e23780feb2be79350fa1
https://doi.org/10.1089/ten.tea.2008.0450
https://doi.org/10.1089/ten.tea.2008.0450
Autor:
Peter Bojo, Robert Langer, Jessica D. Holz, Nicki Watson, Erika Bachelder, Edward A. Botchwey, Rebekah A. Neal, Fredrik Ghosh, Christopher D. Pritchard, Karin Arnér, William L. Neeley
Publikováno v:
Biomaterials. 31:2153-2162
Retinal transplantation experiments have advanced considerably during recent years, but remaining diseased photoreceptor cells in the host retina and inner retinal cells in the transplant physically obstruct the development of graft-host neuronal con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bea1c7fd4527d7ad21901336812d314
https://doi.org/10.1016/j.biomaterials.2009.11.074
https://doi.org/10.1016/j.biomaterials.2009.11.074
Autor:
Jing Yang, Michael J. Young, Sunita Saigal, Henry Klassen, Stephen Redenti, William L. Neeley, Santiago B. Rompani, Robert Langer
Publikováno v:
Biomaterials. 30:3405-3414
Retinal degenerations cause permanent visual loss and affect millions world-wide. Presently, a novel treatment highlights the potential of using biodegradable polymer scaffolds to induce differentiation and deliver retinal progenitor cells for cell r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f119ac462e2a5d5226093f65ed3fd7c6
https://doi.org/10.1016/j.biomaterials.2009.02.046
https://doi.org/10.1016/j.biomaterials.2009.02.046
Autor:
Christopher D. Pritchard, William L. Neeley, Yang D. Teng, Eric J. Woodard, Dou Yu, Robert Langer, Jonathan R. Slotkin
Publikováno v:
Stem Cells. 27:1212-1222
Therapeutic impact of neural stem cells (NSCs) for acute spinal cord injury (SCI) has been limited by the rapid loss of donor cells. Neuroinflammation is likely the cause. As there are close temporal-spatial correlations between the inducible nitric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ffe7656f42708ecd16c86e0a3d8d1e6
https://doi.org/10.1002/stem.26
https://doi.org/10.1002/stem.26
Autor:
William L. Neeley, Michael J. Young, Tejal A. Desai, Sarah L. Tao, Henry Klassen, Robert Langer, Stephen Redenti
Publikováno v:
Biomaterials. 29:418-426
Diseases that cause photoreceptor cell degeneration afflict millions of people, yet no restorative treatment exists for these blinding disorders. Replacement of photoreceptors using retinal progenitor cells (RPCs) represents a promising therapy for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a4082265fbd15e91a7e0f58a2451c7
https://doi.org/10.1016/j.biomaterials.2007.10.007
https://doi.org/10.1016/j.biomaterials.2007.10.007
Autor:
Feng Gu, Sang Soo Hah, James C. Delaney, Steven R. Tannenbaum, John M. Essigmann, Jacquine C. Niles, Paul T. Henderson, William L. Neeley
Publikováno v:
Chemical Research in Toxicology. 18:12-18
The DNA oxidation product 7,8-dihydro-8-oxoguanine (8-oxoG) forms several mutagenic oxidation products, including a metastable oxaluric acid (Oa) derivative. We report here that a synthetic oligonucleotide containing Oa hydrolyzes under simulated "in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09b1db9a3de81b5422c1b991c88261a3
https://doi.org/10.1021/tx049757k
https://doi.org/10.1021/tx049757k
Autor:
Paul T. Henderson, Cynthia J. Burrows, James G. Muller, John M. Essigmann, Steven R. Tannenbaum, James C. Delaney, William L. Neeley
Publikováno v:
Biochemistry. 42:9257-9262
Single-stranded DNA genomes have been constructed that site-specifically contain the 7,8-dihydro-8-oxo-2'-deoxyguanine (8-oxoG) oxidation products guanidinohydantoin (Gh) and the two stable stereoisomers of spiroiminodihydantoin (Sp1 and Sp2). The ci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b2403013d4632ac6d6d2145b51f032c
https://doi.org/10.1021/bi0347252
https://doi.org/10.1021/bi0347252
Publikováno v:
Nanotechnology and Regenerative Engineering ISBN: 9781466585379
Tissue Formation 18 1.4.5 Nucleic Acid Delivery for Tissue Engineering 191.4.5.1 Techniques for Gene Delivery 19 1.4.5.2 Major Barriers in Gene Delivery and Conventional Solutions 20 1.4.5.3 High-Throughput Approach to Identify Novel BiodegradableMat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40bf2a35207857d25de42f1ef153d792
https://doi.org/10.1201/b17444-6
https://doi.org/10.1201/b17444-6
Autor:
Sarah Delaney, James C. Delaney, William L. Neeley, Yuriy O. Alekseyev, Graham C. Walker, Daniel F. Jarosz, John M. Essigmann
Publikováno v:
The Journal of biological chemistry. 282(17)
Reactive oxygen and nitrogen radicals produced during metabolic processes, such as respiration and inflammation, combine with DNA to form many lesions primarily at guanine sites. Understanding the roles of the polymerases responsible for the processi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::640322c6bac3b09357369ddaf6ff4c0b
https://pubmed.ncbi.nlm.nih.gov/17322566
https://pubmed.ncbi.nlm.nih.gov/17322566
Publikováno v:
Biochemistry. 46(5)
The DNA damage product 7,8-dihydro-8-oxo-2'-deoxyguanine (8-oxoG) is a commonly used biomarker of oxidative stress. The mutagenic potential of this DNA lesion is mitigated in Escherichia coli by multiple enzymes. One of these enzymes, MutY, excises a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02ab51e174c641c76cac116db8728d34
https://pubmed.ncbi.nlm.nih.gov/17260974
https://pubmed.ncbi.nlm.nih.gov/17260974